科研論文的構(gòu)思、撰寫和發(fā)表.ppt

科研論文的構(gòu)思、撰寫和發(fā)表,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,2,Why? 為什么要撰寫和發(fā)表論文？ What? 什么是科學研究論文？ 定義 特點 結(jié)構(gòu) How? 如何撰寫科研論文？,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,3,Why? 為什么要撰寫和發(fā)表科研論文？,基礎研究的成果以論文形式表現(xiàn) 發(fā)表論文的質(zhì)量與數(shù)量是衡量科研工作者水平和效率的客觀標準 Publish or Perish!,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,4,Why? 為什么要撰寫和發(fā)表科研論文？,研究結(jié)果只有發(fā)表了，他人才能重復、驗證，結(jié)果才可能成為知識 撰寫和發(fā)表論文是科研工作的最后一道工序 科學研究的目的是發(fā)表,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,5,Why? 為什么要撰寫和發(fā)表科研論文？,科學研究的關(guān)鍵是可重復性、可被他人驗證 科研工作者必須提供書面材料讓同行知道他做了什么、為什么這樣做、怎樣做的、發(fā)現(xiàn)了什么？ 科研工作者不僅要“做”研究，而且要“寫”研究,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,6,Why? 為什么要開設科研論文構(gòu)思、撰寫和發(fā)表課程？,博士應具有構(gòu)思、撰寫和發(fā)表論文的能力 研究生院要求博士研究生發(fā)表SCI論文 研究生及部分導師缺乏科學交流技巧、“寫”科學的訓練,因此增加了博士論文的工作難度、影響了研究生培養(yǎng)的質(zhì)量,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,7,課程的目的,知道 What is a good paper 掌握構(gòu)思要點、基本撰寫方法和技巧 提高分析和表達結(jié)果的能力 避免常見錯誤 提高論文的可讀性 了解論文的投稿、評閱和發(fā)表過程 增加論文被高影響力刊物接受的機率,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,8,主要內(nèi)容,創(chuàng)新性 選題 撰寫要點 結(jié)果的表達 投稿和評閱 常見錯誤,口頭報告 實驗記錄 學位論文 綜述 基金申請 學術(shù)道德,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,9,What? 什么是科學論文？,公開發(fā)表的、描述新研究結(jié)果的書面報告；必須按一定的方式撰寫和發(fā)表 首次出版： 新研究結(jié)果的首次公布 以同行能夠重復實驗、驗證結(jié)論的形式發(fā)表 發(fā)表在同行很容易得到的刊物上或其它媒介（同行評議雜志）上,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,10,科研論文寫作的要求,條理清楚，擺事實、講道理 語言簡單、平實、明確、直接 容易被理解和接受 正確、準確地使用英語 vetral/ventricle; casual/causal 用最少、最短的詞,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,11,科學論文的基本結(jié)構(gòu),Introduction, Methods, Results, and Discussion (IMRAD) I: What and why? 研究什么問題？為什么研究這個問題？ M：How? 如何研究的？ R：What? 發(fā)現(xiàn)了什么？ D：What? 發(fā)現(xiàn)意味著什么？,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,12,標 題,重要性 體現(xiàn)創(chuàng)新點 包含所有關(guān)鍵詞 （檢索） 吸引人 用動詞、句子,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,13,采用動詞（1）,Hippocampal long-term potentiation is reduced by chronic opiate treatment and can be restored by re-exposure to opiates. J. Neurosci. Heterologous activation of protein kinase C stimulates phosphorylation of d-opioid receptor at serine 344 and this results in b-arrestin- and clathrin-mediated receptor internalization. J Biol Chem Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation and this is mediated through interaction of trichosanthin and chemokine receptor. J Exp Med,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,14,采用動詞（2）,Divalent cations and ligands induce conformational changes that are highly divergent among b1 integrins. J Biol Chem Inhibition of CamK II in rat hippocampus attenuates morphine tolerance and dependence. Mol Pharmacol. Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization. J Cell Biochem Carboxyl terminus of delta opioid receptor is required for agonist-dependent receptor phosphorylation. Biochem Biophys Res Commun,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,15,采用動詞（3）,N-methyl-D-aspartate attenuates opioid receptor-mediated G protein activation and this process involves protein kinase C. Mol Pharmacol. Endogenous delta-opioid and ORL1 receptors couple to phosphorylation and activation of p38 MAPK in NG108-15 cells and this is regulated by protein kinase A and protein kinase C. J Neurochem Activation of N-methyl-D-aspartate receptor attenuates acute responsiveness of delta-opioid receptors. Mol Pharmacol Cholecystokinin-B receptor antagonists attenuate morphine dependence and withdrawal in rats. Neuroreport,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,16,采用詞組,Identification of G protein-coupled receptor kinase 2 phosphorylation sites responsible for agonist-stimulated delta-opioid receptor phosphorylation. Mol Pharmacol Differential roles of corticotropin-releasing factor receptor subtypes 1 and 2 in opiate withdrawal and in relapse to opiate dependence. Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase. J Biol Chem Selective interference of b-arrestin 1 with k and d but not m opioid receptor/G protein coupling. J Biol Chem. Differential and tissue-spesific expression of mitochondrial elongation factor Tu and Ts during development. Acta Bioch Bioph Sin Differential efficacies of k agonists to induce homologous desensitization of k opioid receptor. Neurosci Lett,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,17,采用詞組（冒號）,Reactivation of morphine conditioned place preference by drug priming: role of environmental cues and sensitization. Psychopharmacology Five-transmembrane domain structure is sufficient for a G protein coupled receptor: Functional five-transmembrane domain chemokine receptors. Proc Natl Acad Sci USA. Etorphine inhibits cell growth and induces apoptosis in SK-N-SH cells: involvement of pertussis toxin-sensitive G proteins. Neurosci Res Retardation of pain development: a case of recovery from congenital insensitivity to pain. Acta Anaesthesiol Scand,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,18,類似的研究（1）,Differential regulation of beta-arrestin 1 and beta-arrestin 2 gene expression in rat brain by morphine. Neuroscience Acute and chronic morphine treatments and morphine withdrawal differentially regulate GRK2 and GRK5 gene expression in rat brain. Neuropharmacology,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,19,類似的研究（2）,Direct and differential interaction of beta-arrestins with the intracellular domains of different opioid receptors. Mol Pharmacol Direct binding of beta-arrestins to two distinct intracellular domains of the delta opioid receptor. J Neurochem,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,20,類似的研究（3）,Functional expression, activation and desensitization of opioid receptor-like receptor ORL1 in neuroblastoma x glioma NG108-15 hybrid cells. FEBS Lett Endogenous opioid receptor-like receptor in human neuroblastoma SK-N-SH cells: activation of inhibitory G-protein and homologous desensitization. Neuroreport,2019/7/6,科研論文的構(gòu)思、撰寫和發(fā)表,21,Not so good (1),Mechanistic studies of the translational elongation cycle in mammalian mitochondria. Biochim Biophys Acta Molecular characterization and functional expression of opioid receptor-like receptor. Cell Res. Functional expression of o