貝復(fù)舒滴眼液治療角膜潰瘍臨床療效分析

1、貝復(fù)舒滴眼液治療角膜潰瘍臨床療效分析摘要目的探討和分析貝復(fù)舒滴眼液在角膜 潰瘍患者治療中的使用方法和臨床效果。方法整群 選取該院自2014年3月一2015年2月期間收治的角 膜潰瘍患者共96例作為研究對(duì)象，按隨機(jī)原則，分成 對(duì)照組和觀察組各48例，對(duì)照組給予常規(guī)的氧氟沙星 滴眼液進(jìn)行治療，觀察組則使用貝復(fù)舒滴眼液進(jìn)行治 療，使用一個(gè)療程后，將兩組的治療效果進(jìn)行對(duì)比。結(jié) 果 在經(jīng)過(guò)2個(gè)療程治療以后，觀察組患者治療總的有 效率為93.8% (45/48),明顯高于對(duì)照組患者75%,(36/48),觀察組和對(duì)照組患者治療總有效率對(duì)比,差異有統(tǒng)計(jì)學(xué)意義(x 2=6.272, p關(guān)鍵詞貝復(fù)舒滴眼液；角膜

2、潰瘍；治療臨床中圖分類號(hào)r774 文獻(xiàn)標(biāo)識(shí)碼a 文章編號(hào)1674-0742 (2016) 02 (a) -0116-02clinical curative effect analysis of bfgf eye drops intreatment of keratohelcosiswang leihuadian people s hospital, huadian, jilinprovince, 132400 chinaabstract objective to discuss and an a lyze the application method and clinical effect o

3、f bfgf eye drops in treatment of patients with keratohelcosis methods 96 cases of patients with keratohelcosis treated in our hospital from march 2014 to february 2015 were selected as the research object and randomly divided into two groups with 48 cases in each, the control group were treated with

4、 routine ofloxacin eye drops, the observation group were treated with bfgf eye drops, the treatment effect of the two groups was compared after 1 course of treatment. results after 2 courses of treatment , the total treatment effective rate in the observation group was obviously higher than that in

5、the control group 93.8% (45/48) vs (75%, 36/48), the differenee in the total effective rate between the two groups was obvious with statistically significance ( x 2=6.272, p0.05),所以具有可比性。1.2患者入選排除標(biāo)準(zhǔn)該研究選取的患者都沒(méi)有無(wú)不良的耐受性，并且 同意該醫(yī)學(xué)實(shí)驗(yàn)。并排除了有用藥禁忌癥的患者。 1.3具體治療方法對(duì)于對(duì)照組的患者，均給予藥物氧氟沙星滴眼液 進(jìn)行治療，3次/*另通過(guò)人工淚液3次，并在晚上 休息之前使用0.5%的紅霉素眼膏治療；觀察組患者在 對(duì)照組治療的基礎(chǔ)上，加用給貝復(fù)舒滴眼液進(jìn)行治療, 3次/d,每周為一個(gè)療程，連續(xù)使用兩周為觀察期， 直至患者得到痊愈恢復(fù)健康。1.4療效判斷標(biāo)準(zhǔn)該研究以患者在治療后，其癥狀得到明顯的消失 或者改善或者消失為治愈；以患者在治療后，其臨床 癥狀有所改善，且潰瘍面有70%以上的愈合為顯著改 善；以患者在治療后，其臨床癥狀有一定好轉(zhuǎn)，并且 潰瘍面有30%70%的愈合為改善；以患者在治療后, 臨床癥狀無(wú)明顯的變化，并且其潰瘍面積也沒(méi)有出現(xiàn) 明顯的減小為無(wú)效2。總的有效率為顯著改善率、改 善率和治愈率之和。1.5統(tǒng)計(jì)方法全部所得數(shù)據(jù)資料均運(yùn)