CP-409092-hydrochloride-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemECP-409092 hydrochlorideCat. No.: HY-101639ACAS No.: 225240-86-8分式: CHClNO分量: 333.81作靶點(diǎn): GABA Receptor作通路: Membrane Transporter/Ion Channel; Neuronal Signaling儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month

2、溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 41.67 mg/mL (124.83 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.9957 mL 14.9786 mL 29.9572 mL5 mM 0.5991 mL 2.9957 mL 5.9914 mL10 mM 0.2996 mL 1.4979 mL 2.9957 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄的儲(chǔ)備液，再依次添加助溶劑

3、(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (6.23 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (6.23 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMSO

4、 90% corn oilSolubility: 2.08 mg/mL (6.23 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 CP-409092 hydrochlorideGABAA 受體的部分激動(dòng)劑，具有抗焦慮活性 1。REFERENCES1. Kamel A, et al. Metabolism, pharmacokinetics and excretion of the GABA(A) receptor partial agonist (14)CCP-409,092 in rats.Xenobiotica. 2010 Jun;40(6):400-14.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fa