中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀

28八月2024中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀記憶醫(yī)學(xué)術(shù)語(yǔ)方法之一NoChineseassimpleasoneword復(fù)雜學(xué)名記住中文即可中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀GlossaryGinkgoBiloba

[5^iNk^Eu]

銀杏樹maidenhair[5meIdEnheE]

掌葉鐵線蕨intention-to-treatanalysis意向治療分析neurotransmitter[7njuErEtrAns5mitE]神經(jīng)遞質(zhì)bias[baiEs]prejudice偏見(jiàn)depression[di5preFEn]sadness沮喪抑郁tinnitus[ti5naitEs]

ringingintheears耳鳴viscosity[vis5kCsiti]stateofbeingthick粘性中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Ginkgo[5^iNk^Eu]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀maidenhair

掌葉鐵線蕨(少女秀發(fā)蕨)中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀意向治療分析中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀neurotransmitter[7njuErEtrAns5mitE]神經(jīng)遞質(zhì)中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Prejudice

偏見(jiàn)Bias[baiEs]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Sadness抑郁Depression[di5preFEn]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Ringingintheears耳鳴Tinnitus[ti5naitEs]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Stateofbeingthick粘性viscosity[vis5kCsiti]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀記憶公共英語(yǔ)單詞方法之一NoChineseassimpleasonewordPlainEnglish（簡(jiǎn)樸英語(yǔ)）中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Glossaryrobust[rE5bQst]strong精力充沛的substantive[5sQbstEntiv]large大量的cognitive[5kC^nitiv]

gettoknow認(rèn)知的

modification[7mCdifi5keiFEn]makechange修正Unconfounded[kEn5faundid]notconfuse不糊涂的inconsistent[7inkEn5sistEnt]contradictory不一致中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Strong精力充沛的Robust[rE5bQst]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Notconfuse不糊涂的Unconfounded[kEn5faundid]糊涂的

confounded[kEn5faundid]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Contradictory不一致inconsistentshape[7inkEn5sistEnt]中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀GlossaryGinkgoBiloba白果(中文即可)Maidenhair掌葉鐵線蕨(中文即可)Cognitivegettoknow

Substantive

largeAmendmentimproveDepressionsadnessTinnitusringingintheears

Viscositystateofbeingthick中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀《醫(yī)學(xué)英語(yǔ)新教程》第30章-p234–閱讀16句子Ginkgo銀杏中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀《醫(yī)學(xué)英語(yǔ)新教程》第30章-p234–閱讀16句子CochraneLibrary系統(tǒng)綜述文摘中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀LearningObjectivesofSystematicReviewTomasterTitleAuthorStructureofSRResultConclusion

ToknowaboutIntroductionBackgroundObjectiveSearchstrategy掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀標(biāo)題(十分簡(jiǎn)潔)GinkgoBilobaforcognitiveimpairmentanddementia白果治療認(rèn)知損害與癡呆癥（Cochrane系統(tǒng)綜述）掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀標(biāo)題(十分簡(jiǎn)潔)GinkgoBiloba

for

cognitiveimpairmentanddementia白果治療認(rèn)知損害與癡呆癥（Cochrane系統(tǒng)綜述）掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀標(biāo)題固定句式:中心詞＋for短語(yǔ)掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀當(dāng)代(科技)醫(yī)學(xué)英語(yǔ)特點(diǎn)Controlledlanguage中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀作者（≥2）BirksJGrimleyEvansJ掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀（Cochrane綜述文摘）CochraneReview‖SystematicReviewAbstract中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀StructureofCochraneReveiwIntroductionBackgroundObjectiveSearchstrategySelectioncriteriaDatacollectionandanalysisMainresultsReview’sconclusion掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀StructureofCochraneReveiwIntroduction引言BackgroundObjectiveSearchstrategy檢索策略Selectioncriteria選擇標(biāo)準(zhǔn)Datacollectionandanalysis數(shù)據(jù)收集與分析Mainresults主要結(jié)果Review’sconclusion綜述者結(jié)論掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀引言(修訂,截至,被動(dòng))Asubstantive

amendmenttothissystematicreviewwaslastmadeon26August2002.此系統(tǒng)綜述的實(shí)質(zhì)性修改截止2002年8月26日。中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Background

origin起源currentstatus現(xiàn)況mechanism機(jī)制掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Background–originExtractsoftheleavesofthemaidenhairtree,Ginkgobiloba,havelongbeenusedinChinaasatraditionalmedicineforvariousdisordersofhealth.在中國(guó)，從掌葉鐵錢蕨白果樹葉精華作為傳統(tǒng)藥物，長(zhǎng)期用于治療各種疾病。

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Background–status②

Astandardizedextract

iswidely

prescribedinGermanyandFranceforthetreatmentofarangeofconditionsincludingmemoryandconcentrationproblems,confusion,depression,anxiety,dizziness,tinnitusandheadache.

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀背景–現(xiàn)況②一種廣泛用于德國(guó)與法國(guó)的標(biāo)準(zhǔn)萃取物可治療多種疾病，包括記憶與思想集中病癥、意識(shí)模糊、抑郁、焦慮、頭暈、耳鳴與頭痛。

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Background-mechanism③Themechanismsofactionarethoughttoreflecttheactionofseveralcomponentsoftheextractandincludeincreasing

bloodsupplybydilatingbloodvessels,reducingbloodviscosity,modificationofneurotransmittersystems,andreducingthedensityofoxygenfreeradicals.

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀背景–機(jī)制③有人認(rèn)為，若干成分的作用機(jī)制是擴(kuò)張血管、降低血液粘滯度、改善神經(jīng)遞質(zhì)系統(tǒng)，以及減少氧游離基密度而增加血供

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀3.Objective-explicit鮮明

Theaimofthereviewistoassesstheefficacyandsafety

ofGinkgobilobaforthetreatment

ofpatientswithdementiaorcognitivedecline.本綜述目標(biāo)是評(píng)估白果治療癡呆癥或認(rèn)知功能減退的有效性與安全性。

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Searchstrategy–3T

TimeTypesTerms中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Strategy–Time&Types

Trialwereidentifiedon26June2002throughasearchoftheCDCIG……中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀synonym同義詞&asterisk*

Thesearchtermsusedwereginkgo*,tanakan,EGB-761,EGB761and"EGB761".所用檢索術(shù)語(yǔ)為ginkgo*、tanakan、EGB-761、EGB761與“EGB761”。中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Selectioncriteria-phrase+clauseAllrelevant,unconfounded,

randomized,double-blindcontrolledstudies,inwhichextractsofGinkgobilobaatanystrengthandoveranyperiodwerecomparedwithplacebofortheir

effectsonpeoplewithacquiredcognitiveimpairment,includingdementia,ofanydegreeofseverity.中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀收錄標(biāo)準(zhǔn)收錄所有與白果萃取物（任何濃度與任何療程）治療獲得性認(rèn)知損害（包括任何類型的癡呆癥）相關(guān)的正規(guī)隨機(jī)雙盲安慰劑對(duì)照研究文獻(xiàn)。

中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀collection&analysis-metaDataforthemeta-analysesarebasedonreportedsummarystatisticsforeachstudy.供薈粹分析分析的資料取自每個(gè)研究的發(fā)表總結(jié)性統(tǒng)計(jì)。

中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Mainresults–先總后分General:1-4Division(benefit):5-7

(thesamesentencepattern)Summary(adverse):8-9掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Mainresults–先總–概括Overall,thereare

nosignificantdifferencesbetweenGinkgoandplacebointheproportionofparticipantsexperiencingadverseevents.在總體上，接受白果與安慰劑受試者的不良反應(yīng)事件無(wú)顯著差異。

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Mainresults–先總-metaThereare

benefits(主語(yǔ))associatedwithGinkgo(doselessthan200mg/day)comparedwithplaceboatlessthan12weeks(54/63showedimprovementcomparedwith20/63,OR15.32,95%CI

5.90to39.80,P=<0.0001).掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Results–統(tǒng)計(jì)判斷掌握a/b效應(yīng)概率陽(yáng)性數(shù)/總數(shù)-54/63OR(優(yōu)勢(shì)比)陽(yáng)性概率/陰性概率小樣本-數(shù)越大，優(yōu)勢(shì)比大大樣本-數(shù)字小，優(yōu)勢(shì)比也大95%CI(可信區(qū)間)無(wú)零，數(shù)字大，顯著;5.9-39.8有零，≥0即顯著P值0.05>P>0.01顯著意義≤0.001極顯著意義中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Mainresults-先總-meta與安慰劑對(duì)照組相比，至少在12周以內(nèi)顯示白果（劑量>200mg/日）相關(guān)效益（56/43比20/63，優(yōu)勢(shì)比15.32，95%可信區(qū)間5.90至39.80，P=<0.0001）。

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Mainresults–3divisionCognitionshows…(differentdata.)Activitiesshow…//.Measuresofmoodshow…//.Division–后分(療效)掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Mainresults–division-metaThereare

benefits(主語(yǔ))associatedwithGinkgo(doselessthan200mg/day)comparedwithplaceboatlessthan12weeks(54/63showedimprovementcomparedwith20/63,OR15.32,95%CI5.90to39.80,P=<0.0001).掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀samepatternwithdifferentsubjectsanddataCognitionshowsbenefitforGinkgo(doselessthan200mg/day)comparedwithplaceboat12weeks(SMD-0.57,95%

CI-1.09,-0.05,P=0.03,randomeffectsmodel).

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀samepatternwithdifferentsubjectsanddataActivitiesshowsbenefitforGinkgo(doselessthan200mg/day)comparedwithplaceboat12weeks(SMD-0.57,95%

CI-1.09,-0.05,

P=0.03,randomeffectsmodel).

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀samepatternwithdifferentsubjectsanddataMeasuresofmood…showsbenefitforGinkgo(doselessthan200mg/day)comparedwithplaceboat12weeks(SMD-0.57,95%CI-1.09,-0.05,P=0.03,randomeffectsmodel).

掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀當(dāng)代(科技)醫(yī)學(xué)英語(yǔ)特點(diǎn)Controlledlanguage中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Reviewers‘conclusionsMeritsImperfectProspect掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Reviewers‘conclusions–優(yōu)點(diǎn)Ginkgobilobaappearstobesafeinusewithno

excesssideeffectscomparedwithplacebo.應(yīng)用白果相對(duì)安慰劑無(wú)過(guò)度副作用，顯得(似乎)安全。掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Reviewers‘conclusions–說(shuō)明Manyoftheearlytrialsusedunsatisfactorymethods,weresmall,andwecannot

excludepublicationbias.許多早期試驗(yàn)應(yīng)用效果不滿意者多為小型研究,綜述者不能排除論文偏倚。掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Reviewers'conclusions-優(yōu)點(diǎn)Overallthereis

promisingevidenceofimprovementincognitionandfunctionassociatedwithGinkgo.總體上講，白果改善認(rèn)知與功能依據(jù)前景良好。掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Reviewers‘conclusions–不足However,thethreemoremoderntrialsshow

inconsistentresults.然而，有３個(gè)以上當(dāng)代臨床試驗(yàn)的結(jié)果不一致。掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Reviewers’conclusions–展望Thereisneedforalargetrialusingmodernmethodologyandpermittinganintention-to-treatanalysistoproviderobustestimatesofthesizeandmechanismofanytreatmenteffects.尚需應(yīng)用現(xiàn)代的方法學(xué)與“意向治療分析”大型臨床試驗(yàn)，以提供任何治療效應(yīng)大小的有力依據(jù)與機(jī)制。掌握中醫(yī)藥學(xué)循證醫(yī)學(xué)文獻(xiàn)閱讀Summary–keypointsTitle:干預(yù)+for+病癥Author:≥2,independently

StructureofSR:8