16α-Hydroxy-11-keto-prednisolone-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemE16α-Hydroxy-11-ketoprednisoloneCat.No.:HY-W778340CASNo.:3754-05-0分?式:C??H??O?分?量:374.43作?靶點(diǎn):DrugMetabolite;GlucocorticoidReceptor作?通路:MetabolicEnzyme/Protease;Immunology/Inflammation;VitaminDRelated/NuclearReceptor儲(chǔ)存?式:Powder-20°C3yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:116.67mg/mL(311.59mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM2.6707mL13.3536mL26.7073mL5mM0.5341mL2.6707mL5.3415mL10mM0.2671mL1.3354mL2.6707mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。BIOLOGICALACTIVITY?物活性16α-Hydroxy-11-ketoprednisolone(compoundM-X)Budesonide(HY-13580)的代謝物。Budesonide是?種吸?型糖?質(zhì)類醇，具有?服活性的糖?質(zhì)激素受體(glucocorticoidreceptor)激動(dòng)劑。Budesonide?泛?于研究哮喘、?炎和炎癥性腸病。REFERENCES1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemE[1].MataboschX,etal.Identificationofbudesonidemetabolitesinhumanurineafteroraladministration.AnalBioanalChem.2012Aug;404(2):325-40.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax/p>