危險(xiǎn)性分析的原則及其在食品安全中的應(yīng)用.ppt

1,GeneralPrinciple歐洲污染水平/歐洲膳食結(jié)構(gòu),攝入量人群危險(xiǎn)度(ng/人/天)(個(gè)肝癌/年/10萬人)限量20g/kg190.0041(0.0006-0.01)限量10g/kg180.0039(0.0006-0.01)相差2個(gè)肝癌/年/億人,30,例2.HBsAg()25%;中國污染水平/遠(yuǎn)東膳食結(jié)構(gòu),攝入量人群危險(xiǎn)度(ng/人/天)(個(gè)肝癌/年/10萬人)限量20g/kg1250.17(0.03-0.3)限量10g/kg1030.14(0.02-0.3)相差300個(gè)肝癌/年/億人*1990-92年全國肝癌死亡率20/10萬,31,CCFHACTIVITIES,32ndCCFH（1999）DecidedtoproceedinMRAonthebasisofpathogen/commoditycombinations；Elaboratedandagreedontentativeprioritylistofpathogen/commoditycombinations決定對病原食品組合進(jìn)行微生物危險(xiǎn)性評估，并提出暫定優(yōu)先組合,32,CCFHDraftinggroups食品衛(wèi)生法典委員會起草工作組,L.monocytogenesinready-to-eatfood(Germany)即食食品中的單增李斯特菌Salmonellaspp.inpoultry(Sweden)禽肉中的沙門氏菌Campylobacterspp.inpoultry(Netherlands)禽肉中的空腸彎曲菌Vibriospp.inseafood(UnitedStates)海產(chǎn)品中的副溶血性弧菌EnterohemorrhagicE.coliinmeat(UnitedStates)肉食品中的出血性大腸桿菌,33,WhyRAisneededinChina？我國為什么要進(jìn)行危險(xiǎn)性分析？,WTOCODEX/GBFOODINDUSTRYFOODSAFETYCONTROLGovernmentConsumersHEALTHPROTECTIONLifequalityknowledge,國際貿(mào)易食品法典/國家標(biāo)準(zhǔn)體系食品工業(yè)食品安全控制政府消費(fèi)者保護(hù)消費(fèi)者健康生活質(zhì)量的提高對食品安全知識的需求,34,CaseinChinaTheControloftheDeterioratedSugarcaneFoodPoisoning,FreshsugarcanegrowninsouthernareaofChinaShipped,storedandsoldthroughthewinterseasoninthenorthernpartsofChinaContaminatedsugarcanecouldcausefatalfoodpoisoningwhensoldinthenextspring,35,Sugarcanepoisoning,ThefirstoutbreakofunknowncausessugarcanepoisoningoccurredinHenanProvincein1972From1972to1989:No.ofoutbreak:217No.ofcases:884No.ofdeaths:88Averagefatality:10%IdentifiedasaprioritytoassessandcontrolbyMOH,36,Etiologyandriskassessment,EtiologyandcausesstudywerebeencarriedoutbytheChineseAcademyofPreventiveMedicinein1980sArthriniumspp.wasthepathogenicfungus;3-nitropropionicacid(3-NPA)producedbyA.spp.wasprovedtobethecausativecompoundAssessmentwasmadeaccordingtocase-basedstudies,epidemiologicalandlaboratorystudies,37,Decisionmakingandmanagementactivities,Basedondiscoveryandassessment,MOHpromulgated:Diagnosticcriteriaandprinciplesforthemanagementofdeterioratedsugarcanepoisoning(WS/T10-1996);MethodsfortheisolationandidentificationofArthriniumstrainsandanalyzing3-nitropropionicacid(GB47689.16)MOHissuedanotificationonthepreventionandcontrolofDSPtoallprovincesofChinaAnationalhealthcampaignforpreventionandcontrolofthepoisoningwaslaunched,38,Goodresults,Asaresultoftheseefforts,sugarcanepoisoninghasbeensatisfactorycontrolledNotypicalcaseswerereportedinChinainthelast10years!,39,FAO/WHOActivatesinChina,WorkshoponMicrobiologicalRiskAssessmentSponsoredbyFAO/ILSI/WHO/MOH,May10-11,2002BeijingQuantitativeMicrobiologicalRiskAssessmentTrainingCourse(DavidVose)SponsoredbyWHO/INFS,May13-24,2002BeijingNationalWorkshoponIntroductiontoRiskAnalysisintheFisheryIndustrySponsoredbyFAO/INFOYU,Aug12-23,2002Shanghai,40,Riskanalysis-concludingsummary,RiskanalysisanditscomponentsProvideatoolformanaging