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1、solae confidentialsolae confidential global global clinical nutrition clinical nutrition overviewoverview(based on 2009 kalorama report and 2010 gia clinical nutrition report) may update, 2011 may update, 2011solae confidentialsolae confidentialthree products categories of clinical nutritionenteral

2、nutritionenteral nutrition represents a provision of fulfilling the bodys nutritional requirements by using a tube into small intestine or stomach. patients suffering from a disease or permanent non-function of structures, which commonly allow supply of food to the small bowel, require enteral nutri

3、tion. also, patients suffering from small bowel diseases that impair their oral diets digestion and absorption capability depend on enteral nutrition. both require tube-based feedings to supply enough nutrients for maintaining the patients strength and weight in proportion to overall health. enteral

4、 nutrition is prescribed only when people are not able to intake food or optimum quantities of food due to illness. enteral nutrition is applied only when a patients impairment is permanent.- including pediatric and adult formulas-including oral supplements and tube supplementsparenteral nutritionpa

5、renteral nutrition is a specialized liquid food diet added to the blood via an intravenous catheter. parenteral nutrition is described as the source of essential nutrients evading the digestive system. such form of nutrition becomes important in situations where ingesting sufficient nutrients throug

6、h the enteral/oral route is impossible. parenteral nutrition is offered to children, infants, and adults. additionally, the nutrition is supplied for a shorter duration and removed once the person begins normal eating. parenteral nutrition is the least favored choice because of the higher cost and t

7、he higher complication rate. - including intravenously delivered formulas- including infant, pediatric, and adult productsinfant nutritioninfants are required to intake other nourishing foods besides breast milk after 5-6 months of birth. infants experience fast growth as their bones, organs, facial

8、 features and joints are under formation. poor nutrition leads to diseases, weakens the childs body, and also reduces beauty of facial features. infant nutrition segment covers milk-based, soy-based, and special needs products.- including infant formulas 0-12 months- including follow-on formulas tod

9、dlers 12-36 monthssolae confidentialsolae confidentialtotal market size and forecastsolae confidentialsolae confidentialmarkets by geographic region- global clinical nutritionin the global clinical nutrition market, six geographical markets are outlined in below table: the world clinical nutrition p

10、roducts market is estimated at us$24.8 billion in 2010. the market is expected to grow further to reach us$34.5 billion in 2015, reflecting a cagr of 8.6%. the us and european regions accounted for more than 60% of the total global clinical nutrition products market in 2009. however, the two markets

11、 are expected to lose share to china and rest of world gradually. unlike european and the us markets, the chinese market is expected to increase its share from 7.5% in 2009 to 10.5% in 2015. further, the chinese clinical nutrition products market is poised to register the fastest growth of about 14.

12、1% over the period 2006-2015. world recent past, current and future analysis for clinical nutrition products by geographic region us, japan, europe, china, and rest of world markets independentlyanalyzed with annual sales figures in us$ million for years 2006 through 2015.20062008solae confidentials

13、olae confidentialmarkets by geographic region- global clinical nutritionworld clinical nutrition products market accounted for us$ 21.9 billion in year 2008 with nestle/novartis as the leading player constituting a share of 18.5%. abbott closely followed nestle and accounted for a share of 18.1%, wh

14、ile fresenius kabi bagged the third leading position with a share of 17.9% in 2008.the world clinical nutrition market is being fueled by two drivers that include market demographics and new product developments. the global clinical nutrition market is highly competitive and hosts few leading player

15、s that include danone, baxter international, nestle, mead johnson, abbott laboratories, wyeth, pbm products, fresenius kabi, and b. braun. further, the competition is mainly due to the developed regions including the us, western europe, and japan. further, a number of players are extending presence

16、across underdeveloped regions such as china and are increasingly offering competition to developed markets across the world. the introduction of new clinical nutrition products for paraenteral therapies is expected to replace older products. the clinical nutrition industry is burgeoning on account o

17、f growth in the usage of homecare, which is fueling demand for easy to use products.solae confidentialsolae confidentialindustry snapshot global clinical nutritionleading players in the global clinical nutrition market (2008): percentage breakdown of value sales for nestle/novartis, abbott, freseniu

18、s kabi, numico/danone, b. braun, baxter, and others. (source: gia)leading suppliers clinical nutrition revenues and significant segments of participation, 2008solae confidentialsolae confidential1.a enteral nutrition- generalenteral nutrition for patients aged 21 and olderthe patient needs to be dia

19、gnosed with a barrier towards ingestion, absorption or digestion of dailyfood. the patient is also diagnosed of hepatic or renal failure. standard products with 1-2 kcal/ml areprescribed if the product is the only source of patients nutrition. the elemental food products areincluded only on symptoms

20、 of mal-absorption conditions. the nutritionally incompetent or modularproducts are not included. the pregnant or lactating females entitled for the special supplementalnutrition program for wic (women, infants, and children) need to obtain enteral products via wic.enteral nutrition for patients bel

21、ow 21 yearsthe commercial enteral food products are included only when such products account for 50% or morethan 50% of the total calorie intake. the patients need to maintain a medical condition that limits theability of ingesting, digesting, or absorbing daily food. the products for in-born metabo

22、lism errors arecovered along with records of suitable diagnosis. elemental diets are prescribed only with records of adiagnosed mal-absorption condition. modular products are recommended for conditions besidesfailure to thrive. also, the requirement of 50% calories is not mandatory for such products

23、.tube feedingnutrition supplied to individuals in forms other than normal intake from mouth is referred to as tubefeeding. in tube feeding a specific liquid diet containing carbohydrates, proteins, mineral, vitamins, and fats is offered via a tube to the small intestine or stomach. tube feeding is o

24、ffered to people ofvarious age groups, starting from infants to children and finally to adults. people survive quite wellon tube feeding throughout the duration of its requirement. tube feeding is deployed for shorter timeintervals, with the tube being removed after the person starts eating normally

25、 again. tube feeding isoffered via various kinds of tubes and one tube is placed via the nose to the bowel or stomach. sucha tube is known as a nasoenteral or nasogastric feeding tube. in some instances, the tube is directlyplaced via the skin to the bowel or stomach. such a process is called jejuno

26、stomy or gastrostomy.solae confidentialsolae confidential1.b global market overview of enteral nutritionthe enteral nutrition market including both oral and tube formulas is relatively stable with a large potential for growth. in 2008, sales for enteral nutrition products increased 12.4% to $8.2 bil

27、lion from $7.3 billion in 2007 and 12.3% over $6.5 billion in 2006. the market primarily consists of adult enteral formulas, while pediatric formulas contribute the remaining sales. demand for enteral products remains steady in the united states and japan while markets in europe are increasing signi

28、ficantly. one factor driving growth is the increased use of enteral products in home care settings, which is continuing to grow worldwide. another factor contributing to growth is the focus on providing nutritionon a disease-specific basis.solae confidentialsolae confidential1.1 industry snapshot en

29、teral nutritionleading players in the global clinical nutrition market (2008): percentage breakdown of value sales for nestle/novartis, abbott, fresenius kabi, numico/danone, b. braun, baxter, and others. world enteral nutrition market is highly consolidated with top three players accounting for mor

30、e than 70% of the market. abbott and nestle bagged the leading positions and accounted for respective shares of 29.5% and 25.3% in year 2007.the enteral nutrition market is further segmented into enteral infant products and enteral adult products. the adult enteral formulations mainly include whole

31、or fractional ingredients including whole oils, fatty acids, phospholipids, whole proteins, peptides, and amino acids. the adult enteral formulations sector is a major market accounting for a share in the overall market. the major players in the adult nutrition market include glaxosmithkline, novart

32、is, nutritek, kao, otsuka pharmaceuticals, biersdoff, nutricia, us dentak, elli lilly, pacific health pharmaceuticals, fujisawa, fresenius kabi enteral nutrition, warner lambert, merck & co., and gillette -oral-b. while the enteral infant products market is governed by mead johnson, wyeth, numic

33、o, and nestle clinical nutrition.(source: gia)solae confidentialsolae confidential1.2 global market overview of enteral nutritionsolae confidentialsolae confidential1.3 global player and china presence of enteral nutritionglobal: the enteral nutrition market is a currently stable, yet highly poised for stronggrowth potential. man

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