時間常數(shù)實用PPT學(xué)習(xí)教案

1、時間常數(shù)實用時間常數(shù)實用第1頁/共22頁第2頁/共22頁第3頁/共22頁第4頁/共22頁RC第5頁/共22頁第6頁/共22頁第7頁/共22頁P(yáng)EFREELV吸氣吸氣呼氣呼氣PIFRVT第8頁/共22頁Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critical Care Med 1995; 23(6):1117-1122流量(L/min)容

2、積(L)0VtPEFR第9頁/共22頁Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critical Care Med 1995; 23(6):1117-1122流量(L/min)容積(L)0VtPEFRTauE = Vt / PEFR第10頁/共22頁第11頁/共22頁第12頁/共22頁Brunner JX, Laubscher TP, B

3、anner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critical Care Med 1995; 23(6):1117-1122模擬肺y = 0.975x + 0.169r2 = 0.974動物試驗(犬)y = 1.033x + 0.038r2 = 0.969第13頁/共22頁Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to m

4、easure total expiratory time constant based on the passive expiratory flow-volume curve. Critical Care Med 1995; 23(6):1117-1122第14頁/共22頁Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 16

5、12-1618第15頁/共22頁Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618RCfv100 = Vt / (V100, exp Vend, ex)RCfv75 = 0.75 x Vt / (V75, exp Vend, ex)RCfv50 = 0.50 x Vt / (V50, exp Vend, ex

6、)RCfv25 = 0.25 x Vt / (V25, exp Vend, ex)第16頁/共22頁Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618重度COPD中度COPD其他病因RCint2.88 1.611.02 0.400.65 0.28RCfvp0.75 0.200.70 0.190.60 0.10

7、RCfv1000.85 0.180.79 0.220.63 0.12RCfv752.84 1.531.05 0.320.72 0.18RCfv503.42 1.61 1.25 0.440.84 0.39RCfv254.20 1.991.47 0.571.06 0.63第17頁/共22頁Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618第18頁/共22頁Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated pati