科研實(shí)習(xí)機(jī)會(huì)--麻生明課題組

1、科研實(shí)習(xí)機(jī)會(huì)-麻生明課題組為了讓化學(xué)系本科生有機(jī)會(huì)走近課題組，了解化學(xué)研究，加強(qiáng)與研究生的交流，充分利用研究資源，提高化學(xué)系大學(xué)本科生的實(shí)踐動(dòng)手能力、科研能力和自主創(chuàng)新能力，本課題組暑期在06級(jí)本科生中設(shè)立科研實(shí)習(xí)崗位。有關(guān)事項(xiàng)如下： 申請(qǐng)條件：化學(xué)系06級(jí)本科生，對(duì)化學(xué)有濃厚的興趣，有志于科學(xué)研究，具有良好的英語(yǔ)讀寫能力，工作踏實(shí)認(rèn)真，責(zé)任心強(qiáng)，吃苦耐勞。工作內(nèi)容： 協(xié)助博士生開展科學(xué)研究工作。課題組安排博士生（一對(duì)一）專門培訓(xùn)學(xué)生的實(shí)驗(yàn)技能、查閱化學(xué)文獻(xiàn)及研究方法指導(dǎo)。工作時(shí)間及地點(diǎn)：時(shí)間：7月4日-7月31日。地點(diǎn)：浙江大學(xué)玉泉校區(qū)化學(xué)系教八-831，621。待遇：工作期間住宿在玉泉校區(qū)

2、學(xué)生宿舍，費(fèi)用由課題組承擔(dān)。根據(jù)工作表現(xiàn)提供600以上的生活費(fèi)。名額：3-5名。崗位申請(qǐng)：請(qǐng)申請(qǐng)勤工助學(xué)崗位的同學(xué)填寫申請(qǐng)表（附件1）并發(fā)送到masm，經(jīng)課題組初審后于3月18日前組織面試，擇優(yōu)錄取。聯(lián)系地址： 浙江大學(xué)玉泉校區(qū)化學(xué)系教八-829 E-mail: masm麻生明研究小組學(xué)生信息表姓名性別出生年月日身份證號(hào)碼聯(lián)系電話畢業(yè)學(xué)校英語(yǔ)六級(jí)興趣愛好個(gè)人志向家庭住址（省、市）父母職業(yè)（農(nóng)民，教師等）父親： 母親： 進(jìn)浙大時(shí)間 年 月麻生明課題組簡(jiǎn)介研究方向：1 聯(lián)烯的親電加成反應(yīng)；2 金屬參與的有機(jī)反應(yīng)；3 酶催化的有機(jī)合成方法學(xué)研究；4 聯(lián)烯的自由基化學(xué)等。實(shí)驗(yàn)條件和儀器裝備：1. 30

3、0 MHz 核磁共振儀（Bruker） 2. 手套箱（無(wú)水無(wú)氧操作）3高效液相色譜儀（Agilent） 4. 氣相色譜儀（Agilent）5. 手性色譜柱陣列 6. 恒溫?fù)u床（瑞士）7. 低溫控制儀（-80 o C）（日本） 8. 旋轉(zhuǎn)蒸發(fā)儀（Buchi）9. 低溫冰柜、冰箱、油泵、水泵 10. 烘箱，真空干燥箱11.乙炔鋼瓶，氨氣鋼瓶，一氧化碳鋼瓶，氮?dú)怃撈?，液氮，干冰等已畢業(yè)學(xué)生： 郝學(xué)士（2003年博士畢業(yè)），潘峰（2004年碩士畢業(yè)），孟曉峰（2004年碩士畢業(yè)），傅春玲（2005年博士畢業(yè)），周超（2007年博士畢業(yè)）。在讀學(xué)生：2003級(jí)直博生2名（陸展，馬志超），2004級(jí)直博生

4、1名（李晶），2005直博生2名(鄧友前，陳國(guó)飛)，2006春博士生2名（姜昕鵬，何廣科），2006直博生1名（孔望清），2007直博生3名（呂博，柴國(guó)璧，方昭）。03年建立課題組以來(lái)在浙大發(fā)表的研究論文：1. PdI2-Catalyzed Coupling Cyclization Reaction Involving Two Different 2,3-Allenols: An Efficient Synthesis of 4-(1,3-Dien-2-yl)-2,5-dihydrofuran Derivatives, Youqian Deng, Jing Li, and Shengming

5、Ma, Chem. Eur. J. 2008, 14, in the press.2. Metal-Catalyzed Enantioselective Allylation in Asymmetric Synthesis, Zhan Lu and Shengming Ma, Angew. Chem. Int. Ed. 2008, 47, 258.3. PdCl2/NaI-Catalyzed Homodimeric Coupling-Cyclization Reaction of 2,3-Allenols: An Efficient Synthesis of 4-(1,3-Dien-2-yl)

6、-2,5-dihydrofuran Derivatives, Youqian Deng, Yihua Yu, and Shengming Ma, J. Org. Chem. 2008, 73, 585.4. An Efficient Approach for Monofluorination via Aqueous Fluorolactonization Reaction of 2,3-Allenoic Acids with Selectfluor, Chao Zhou, Zhichao Ma, Zhenhua Gu, Chunling Fu, and Shengming Ma, J. Org

7、. Chem. 2008, 73, 772.5. Monofluorination via Highly Regioselective Flurohydroxylation Reaction of 3-Aryl-1,2-allenes with Selectfluor, Chao Zhou, Jing Li, Bo L, Chunling Fu, and Shengming Ma, Org. Lett. 2008, 10, 581.6. Iron-Catalyzed Highly Regio- and Stereoselective Conjugate Addition of 2,3-Alle

8、noates with Grignard Reagents, Zhan Lu, Cai Guobi, Shengming Ma, J. Am. Chem. Soc. 2007, 129, 14546.7. Highly Selective Thiiranation of 1,2-Allenyl Sulfones with Br2 and Na2S2O3 : Mechanism and Asymmetric Synthesis of Alkylidenethiiranes, Chao Zhou, Chunling Fu, and Shengming Ma, Angew. Chem. Int. E

9、d. 2007, 46, 4379.8. Studies on Highly Stereoselective Addition-Elimination Reaction of (Methoxycarbonyl) -1,2-allen-4-ols with MX. An Efficient Synthesis of 3-(Methoxycarbonyl)-2-halo-1,3(Z)-dienes, Youqian Deng, Xin Jin, and Shengming Ma, J. Org. Chem. 2007, 72, 5901.9. Highly Regio- and Stereosel

10、ective Copper(I) Chloride-Mediated Carbometallation of 2,3-Allenols with Grignard Reagents, Zhan Lu and Shengming Ma, Adv. Synth. Catal. 2007, 349, 1225.10. Studies on the highly regio- and stereoselective selenohydroxylation of 1,2-allenylic sulfoxides with PhSeCl, Guangke He, Chao Zhou, Chunling F

11、u, and Shengming Ma, Tetrahedron 2007, 63, 3800.11. Studies on electrophilic reaction of Br2 with 1,2-allenylic sulfones. A highly regio- and stereoselective synthesis of 1-phenylsulfonyl-2-bromo-1(E)-alken-3-ols and 1-phenylsulfonyl-2-bromo-1(E),3(E)-butadienes, Chao Zhou, Chunling Fu, and Shengmin

12、g Ma, Tetrahedron 2007, 63, 7612.12. Control of regio- and stereoselectivity in electrophilic additions of allenes, Shengming Ma, Pure and Applied Chemistry 2007, 79(2), 261.13. Electrophilic Interaction of 2,3-Allenoates with PhSeCl. An Unexpected Highly Stereoselective Synthesis of 3-Phenylseleno-

13、4-oxo-2(E)-alkenoates, Guofei Chen, Chunling Fu and Shengming Ma, J. Org. Chem. 2006, 71, 9877.14. Copper(I)-Mediated Highly Stereoselective syn-Carbometalation of Secondary or Tertiary Propargylic Alcohols with Primary Grignard Reagents in Toluene with a High Linear Regioselectivity, Shengming Ma a

14、nd Zhan Lu, Adv. Synth. Catal. 2006, 348, 1894.15. Studies on the Cu(I)-Catalyzed Regioselective anti-Carbometallation of Secondary Terminal Propargylic Alcohols, Zhan Lu and Shengming Ma, J. Org. Chem. 2006, 71, 2655.16. Studies on electrophilic addition reaction of 2,3-allenoates with PhSeCl, Guof

15、ei Chen, Chunling Fu and Shengming Ma, Tetrahedron 2006, 62, 4444.17. Na2S2O4-Promoted Radical Addition Reaction of Perfluoroalkyl Iodides with Allenes and the Pd(0)-Catalyzed Stereoselective Sonogashira Coupling Reaction of Addition Products with Propargyl Alcohol, eShengming Ma, Zhichao Ma, Synlet

16、t 2006, 1263.18. 2，3-聯(lián)烯醇及其衍生物的反應(yīng)，鄧友前，顧振華，麻生明，有機(jī)化學(xué)，2006, 26, 1468。19. Some typical advances in the synthetic applications of allenes, Shengming Ma, Chem. Rev., 2005, 105 , 2829.20. The Observation of First Heck-type Substitution Reaction of Allenes with Aryl Halides, Chunling Fu, Shengming Ma, Org. L

17、ett. 2005, 7, 1607.21. Highly Stereoselecitive Synthesis of 2(E),4-Alkadienoates via the Pd(0)-Catalyzed Reaction of Aryl Halides with 3,4-Alkadienoates, Chunling Fu, Shengming Ma, Org. Lett. 2005, 7, 1705. 22. Efficient Two-step Synthesis of 3-Halo-3-enals or 2-Halo-2-alkenyl ketones from Propargyl

18、ic Bromides via a Unique Cationic 1,2-Aryl Shift in Electrophilic Addition Reaction of 2,3-Allenols with X+(X= Br, I), Chunling Fu, Jing Li, Shengming Ma, Chem. Commun. 2005, 4119.23. Efficient Preparation of 4-Iodofuran-2(5H)-ones by Iodolactonization of 2,3-Allenoates with I2, Chunling Fu, Shengmi

19、ng Ma, Eur. J. Org. Chem. 2005, 2918. 24. Stereoselective Z-Iodoalkoxylation of 1,2-Allenyl Sulfides or Selenides, Chunling Fu, Guofei Chen, Shengming Ma, Tetrahedron 2005, 61, 7768. 25. PhSO2NaInduced Isomerization of 1,2-Allenyl Sulfoxides to 2-Acetylenic Phenyl Sulfoxides Chunling Fu; Shengming M

20、a, Chin. J. Chem. 2005, 23, 729. 26. Studies on the Regio- and Stereoselectivity of Halahydroxylation of 1,2-Allenyl Sulfides or Selenides, Shengming Ma, Xueshi Hao, Xiaofeng Meng, Xian Huang, J. Org. Chem. 2004, 69, 5720.27. Pd-Catalyzed Coupling Reactions Involving Propargylic/Allenylic Species, S

21、hengming Ma, Eur. J. Org. Chem. 2004, 1175. 28. Reaction of PhSeCl or PhSCl with 2,3-Allenic Acids: An Efficient Synthesis of Organoselenium or Organosulfur Substituted Butenolides, Shengming Ma, Feng Pan, Xueshi Hao and Xian Huang, Synlett 2004, 85. 29. Convenient stereoselective synthesis of 3-hydroxy-2-iodo-2(E)-alkenyl sulfides via iodohydroxylation of 1,2-allenyl sulfoxides in the presence of BnSH Chunling Fu, Xian