生物材料轉(zhuǎn)移協(xié)議中英文雙語版

1、XXXXX生物材料轉(zhuǎn)移協(xié)議本協(xié)議確定了關(guān)于提供方向接收方所供應(yīng)的由研究人員研制的特定生物材料的規(guī)定，希望在本協(xié)議的條款和細則的約束下該材料使用于非商業(yè)性研究目的。此材料轉(zhuǎn)移協(xié)議（MTA由,即一家 類型的組織機構(gòu)（接收方），與XXXXX（提供方）簽訂。此協(xié)議于各方最后簽立之日起生效，并按以下條款與細則管轄生物材料的轉(zhuǎn)移和使用。一、定義1 .提供方： XXXXX2 .提供方科學(xué)家：3 .接收方：4 .接收方科學(xué)家：5 .原始材料：6 .材料：原始材料、后代和未改性衍生物，其中不包括（1）改性物質(zhì)（2）由接收方使用材料創(chuàng)制的除了改性物質(zhì)、后代和未改性衍生物之外的物質(zhì)。7 .后代：指源自材料的未改性后

2、代，如源自病毒的病毒、 源自細胞的細胞、 源自微生物的微生物。8 .未改性衍生物：指由接收方創(chuàng)造的各種物質(zhì)，構(gòu)成一種未改性的功能亞基或原始材料的表 達產(chǎn)物，例如未改性細胞系的亞克隆、原始材料的純化或分儲子集，由提供方所供DNA/RNA表達的蛋白質(zhì)，或由雜交瘤細胞系分泌的單克隆抗體。9 .改性物質(zhì)：指接收方創(chuàng)制的、包含和（或）容納材料的物質(zhì)。10 .商業(yè)用途：指向營利性機構(gòu)銷售、出租、授權(quán)、轉(zhuǎn)移材料或其改性物質(zhì)，也包括接收方在內(nèi)的任何機構(gòu)使用材料進行合同研究、篩選化合物庫、或制造供一般銷售的產(chǎn)品，或進行研究行為，目的是向營利性機構(gòu)銷售、出租、授權(quán)、轉(zhuǎn)移材料或改性物質(zhì)。但是，由企業(yè)贊 助的學(xué)術(shù)性研

3、究不應(yīng)被認為是材料或改性物質(zhì)的商業(yè)性用途，除非滿足上述對商業(yè)用途所定義的情況。二、協(xié)議條款1 .提供方保留對材料的所有權(quán)，包括任何包含或混有改性物質(zhì)的材料。2 .接收方對以下材料擁有所有權(quán)：(1)改性物質(zhì)(提供方對其中所含生物材料的權(quán)利保留擁有全的情況除外)；(2)使用材料或改性物質(zhì)創(chuàng)造的非后代、未改性衍生物及改性物質(zhì)(即不包含原始材料、 后代或未改性衍生物)。如上述兩種情況為提供方與接收方的合作成果，則可對共同所有權(quán)進行商議。3 .接收方及接收方科學(xué)家同意如下細則，本材料：(1)僅用于教學(xué)或?qū)W術(shù)性研究；(2)不得使用于人體、臨床試驗或者未經(jīng)提供方書面同意而用于人體的診斷；(3)僅可在接收方研

4、究人員的實驗室中使用，并且在接收方科學(xué)家或其直接監(jiān)管人員的指 導(dǎo)下使用；(4)未經(jīng)提供方事先書面同意不得將材料轉(zhuǎn)移給接收方機構(gòu)內(nèi)的任何人。4 .接收方及接收方科學(xué)家同意向提供方提交在接收方科學(xué)家監(jiān)管下工作人員的任何關(guān)于材料的請求。在某種程度上該材料可供其他科學(xué)家使用， 提供方或提供方科學(xué)家同意制備該材 料給其他科學(xué)家用于重復(fù)接收方的研究實驗， 但須與提供方簽訂該協(xié)議的獨立實施函件或者 與此協(xié)議條款相一致的其他協(xié)議，并且這些科學(xué)家需向提供方補償制備和配送材料的相關(guān)成5 . (1)除原始材料的后代、未改性衍生物和改性物質(zhì)外，接收方和(或)接收科學(xué)家有權(quán) 不受限制地分配由接收方通過使用原始材料研制的

5、產(chǎn)物。(2)在本協(xié)議的獨立實施函件(或一份至少可作為保護提供方權(quán)利的協(xié)議)指導(dǎo)下，接 收方可將改性物質(zhì)分配給非營利組織機構(gòu)用于單純性的科研與教學(xué)。(3)未經(jīng)提供方的書面同意，接收方和(或)接收方科學(xué)家不得將改性物質(zhì)投入商業(yè)用途。接收方應(yīng)認識到，此類商業(yè)用途需獲得提供方的商業(yè)許可， 提供方擁有對包含在改性物 質(zhì)中的材料的所有權(quán)，但沒有義務(wù)對其授予商業(yè)許可。該項條款將防止接收方在其知識產(chǎn)權(quán) 聲明中對改性物質(zhì)、或其制造方法及使用方法授予商業(yè)許可。6 .接收方需知曉該材料有可能用于專利申請。除非在本協(xié)議中明確規(guī)定，否則接收方不擁 有提供方對專利、專利申請書、商業(yè)秘密或其他所有權(quán)的任何明示或默示的許可及

6、其他權(quán)利， 包括提供方對該材料所做的任何改變形式。特別是，接收方并未獲得任何明示或默示的許可表明其可將提供方的材料、改性物質(zhì)或任何相關(guān)的專利投入商業(yè)用途。7 .如果接收方擬將該材料或改性物質(zhì)投入商業(yè)用途，須同意，在此之前與提供方商議并確立一份商業(yè)許可的條款。接收方應(yīng)了解，提供方?jīng)]有義務(wù)授予接收方此類許可，而且可能會授予他人一些專用性或非專用性的商業(yè)許可，或出售、轉(zhuǎn)讓材料的全部/部分權(quán)利給任何第三方，并受到已有的所有權(quán)和對政府應(yīng)盡的義務(wù)條款的約束。8 .接收方通過使用該材料而獲得的發(fā)明可自由提出專利申請，但需告知提供方在專利申請 中已聲明的該材料的改性物質(zhì)、制備方法或用途等。9 .根據(jù)本協(xié)議提供

7、的任何材料都被理解為實驗性質(zhì)，并可能具有危險性。提供方對此不作 任何陳述和任何明示或默示的保證。對于任何適銷性、特定目的適用性以及不侵犯任何專利權(quán)、版權(quán)、商標(biāo)或其他所有權(quán)的用途，提供方不做任何明示或默示的保證。10 .接收方應(yīng)對可能發(fā)生在該材料使用、儲存或棄置過程中造成的損害承擔(dān)賠償責(zé)任，法律禁止范圍的除外。接收方在使用該材料時發(fā)生重大過失、故意的不當(dāng)行為所造成的任何損失、索賠、需求，或有關(guān)的所有第三方索賠、損失和損害，提供方將不承擔(dān)任何責(zé)任，法律另有 規(guī)定的除外。11 .此協(xié)議不得被解釋為因使用該材料或改性物質(zhì)而阻止或延誤了研究結(jié)果的發(fā)表。接收方科學(xué)家同意在所有的出版物中對材料來源予以適當(dāng)?shù)?/p>

8、致謝。12 .接收方同意遵照法律法規(guī)使用該材料。13 .本協(xié)議在以下日期到來之初即可終止：(1)當(dāng)本材料可輕易從第三方如試劑公司或公共倉庫獲得時；(2)當(dāng)接收方已完成利用本材料進行的最新研究時；(3)任何一方書面通知中提出的三十日期限或失效日前的期限，或(4)在實施函件中指定的日期。如果：1)協(xié)議是因條款13 (1)而終止，則接收方從后續(xù)可用的來源中獲得該材料時受到 的限制性條款最少；2)協(xié)議是因13 (2)或(4)終止，則接收方停止使用該材料并在提供 方的指導(dǎo)下，返還或銷毀所有剩余材料。接收方可自行決定，銷毀或保留改性物質(zhì)，但要受到其相應(yīng)的條款約束；3)提供方在13 (3)的情況下終止協(xié)議，

9、且不是因為違反協(xié)議或類 似于健康風(fēng)險、專利侵權(quán)等原因，則提供方將根據(jù)接收方要求將合同有效終止日期延長一年， 以使接收方完成相應(yīng)研究。截止到合同有效終止日期，或延期后的有效終止日期，接收方應(yīng) 停止使用材料，并在提供方的要求和指引下返還或銷毀剩余材料。接收方可自行決定，銷毀或保留改性物質(zhì)，但要受到其相應(yīng)的條款約束。14 .提供該材料原則上是不收取費用的，但是，為補償提供方制備及配送該材料的成本，接收方可適當(dāng)支付部分運輸費用。如提供方要求收取費用，則需在單獨的實施函件中注明數(shù)額。15 .本協(xié)議中英文版本各2份，提供方和接收方各執(zhí) 1份，均具有同等法律效力。各方的授權(quán)代表在下面簽字，即表示他們已經(jīng)閱讀

10、、理解并同意此材料轉(zhuǎn)移協(xié)議中所 載的條款和細則，特此簽字為證。提供方：XXXXX地 址：XXXXXX 510275提供方授權(quán)人：職務(wù)：簽字：日期:提供方科研人員：簽字：日期:接收方：地址：接收方授權(quán)人：職務(wù)：簽字：日期:接收方科研人員：簽字：日期:* UNIVERSITYUNIFORM BIOLOGICAL MATERIAL TRANSFER AGREEMENTThis Agreement sets out the understanding of the parties with respect to the provision of certain biological material

11、created by researchers at the Provider to the Recipient, which wishes to use the material for non-commercial research purposes subject to the terms and conditions of this Agreement. This Material Transfer Agreement (" MTA1 ) is between the, a typeorganization ( a Recipient ” *他 theUniversity (

12、a Provider " ).This MTA is effective as of the last date of execution by the parties and governs the transfer and use of all Biological Materials under the terms and conditions set forth below.Definitions1. PROVIDER: * University2. PROVIDER SCIENTIST:3. RECIPIENT:4. RECIPIENT SCIENTIST:5. ORIGI

13、NAL MATERIAL:6. MATERIAL:ORIGINAL MATERIAL, PROGENY , and UNMODIFIED DERIV ATIVES. The MATERIAL shall not include: (a) MODIFICA TIONS, or (b) Other substances created by the RECIPIENT through the use of the MATERIAL which are not MODIFICA TIONS, PROGENY , or UNMODIFIED DERIV ATIVES.7. PROGENY: Unmod

14、ified descendant from the MATERIAL, such as virus from virus, cell from cell, or organism from organism.8. UNMODIFIED DERIVATIVES: Substances created by the RECIPIENT which constitute an unmodified functional subunit or product expressed by the ORIGINAL MA TERIAL. Some examples include: subclones of

15、 unmodified cell lines, purified or fractionated subsets of the ORIGINAL MATERIAL, proteins expressed by DNA/RNA supplied by the PROVIDER, or monoclonal antibodies secreted by a hybridoma cell line.9. MODIFICA TIONS: Substances created by the RECIPIENT which contain/incorporate the MATERIAL.10. COMM

16、ERCIAL PURPOSES: The sale, lease, license, or other transfer of the MA TERIAL or MODIFICATIONS to a for-profit organization. COMMERCIAL PURPOSES shall also include uses of the MATERIAL or MODIFICATIONS by any organization, including RECIPIENT, to perform contract research, to screen compound librari

17、es, to produce or manufacture products for general sale, or to conduct research activities that result in any sale, lease, license, or transfer of the MA TERIAL or MODIFICATIONS to a for-profit organization. However, industrially sponsored academic research shall not be considereda use of the MATERI

18、AL or MODIFICATIONSforCOMMERCIAL PURPOSES per se unless any of the above conditions of this definition are met.Material Transfer1. The PROVIDER retains ownership of the MATERIAL, including any MATERIAL contained or incorporated in MODIFICA TIONS.2. The RECIPIENT retains ownership of: (a) MODIFICA TI

19、ONS (except that, the PROVIDER retains ownership rights to the MATERIAL included therein), and (b) those substances created through the use of the MATERIAL or MODIFICA TIONS, but which are not PROGENY, UNMODIFIED DERIVATIVES or MODIFICA TIONS (i.e., do not contain the ORIGINAL MATERIAL, PROGENY , UN

20、MODIFIED DERIVATIVES). If either 2 (a) or 2 (b) results from the collaborative efforts of the PROVIDER and the RECIPIENT, joint ownership may be negotiated.3. The RECIPIENT and the RECIPIENT SCIENTIST agree that the MATERIAL:(a) is to be used solely for teaching and academic research purposes; (b) w

21、illnot be used in human subjects, in clinical trials, or for diagnostic purposes involving human subjects without the written consent of the PROVIDER; (c) is to be used only at the RECIPIENTorganization and only in the RECIPIENTSCIENTIST's laboratory under the direction of the RECIPIENT SCIENTIS

22、T or others working under his/her direct supervision; and (d) will not be transferred to anyone else within the RECIPIENT organization without the prior written consent of the PROVIDER.4. The RECIPIENT and the RECIPIENT SCIENTIST agree to refer to the PROVIDER any request for the MATERIAL from anyon

23、e other than those persons working under the RECIPIENT SCIENTIST's direct supervision. To the extent supplies are available, the PROVIDER or the PROVIDER SCIENTIST agrees to make the MATERIAL available, under a separate implementing letter to this Agreement or other agreement having terms consis

24、tent with the terms of this Agreement, to other scientists who wish to replicate the RECIPIENT SCIENTIST' s research; provided that suchother scientists reimburse the PROVIDER for any costs relating to the preparation and distribution of the MATERIAL.5.(a) The RECIPIENT and/or the RECIPIENT SCIE

25、NTIST shall have the right, without restriction, to distribute substances created by the RECIPIENT through the use of the ORIGINAL MATERIAL only if those substances are not PROGENY , UNMODIFIED DERIV ATIVES, or MODIFICA TIONS.(b) Under a separate implementing letter to this Agreement (or an agreemen

26、t at least as protective of the PROVIDER's rights), the RECIPIENT may distribute MODIFICATIONS to NON-PROFIT ORGANIZATION(S) for research and teaching purposes only.(c) Without written consent from the PROVIDER, the RECIPIENT and/or the RECIPIENT SCIENTIST may NOT provide MODIFICATIONS for COMME

27、RCIAL PURPOSES. It is recognized by the RECIPIENT that such COMMERCIAL PURPOSES may require a commercial license from the PROVIDER and the PROVIDER has no obligation to grant a commercial license to its ownership interest in the MATERIAL incorporated in the MODIFICATIONS. Nothing in this paragraph,

28、however, shall prevent the RECIPIENT from granting commercial licenses under the RECIPIENT's intellectual property rights claiming such MODIFICA TIONS, or methods of their manufacture or their use.6. The RECIPIENT acknowledges that the MATERIAL is or may be the subject of a patent application. E

29、xcept as provided in this Agreement, no express or implied licenses or other rights are provided to the RECIPIENT under any patents, patent applications, trade secrets or other proprietary rights of the PROVIDER, including any altered forms of the MATERIAL made by the PROVIDER. In particular, no exp

30、ress or implied licenses or other rights are provided to use the MATERIAL, MODIFICATIONS, or any related patents of the PROVIDER for COMMERCIAL PURPOSES.7. If the RECIPIENT desires to use or license the MATERIAL or MODIFICA TIONS forCOMMERCIAL PURPOSES, the RECIPIENT agrees, in advance of such use,

31、to negotiate in good faith with the PROVIDER to establish the terms of a commercial license. It is understood by the RECIPIENT that the PROVIDER shall have no obligation to grant such a license to the RECIPIENT, and may grant exclusive or non-exclusive commercial licenses to others, or sell or assig

32、n all or part of the rights in the MATERIAL to any third party(ies), subject to any pre-existing rights held by others and obligations to the government.8. The RECIPIENT is free to file patent application(s) claiming inventions made by the RECIPIENT through the use of the MATERIAL but agrees to noti

33、fy the PROVIDER upon filing a patent application claiming MODIFICATIONS or method(s) of manufacture or use(s) of the MATERIAL.9. Any MATERIAL delivered pursuant to this Agreement is understood to be experimental in nature and may have hazardous properties. The PROVIDER MAKES NO REPRESENTA TIONS AND

34、EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED. THERE ARE NO EXPRESS OR IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR THAT THE USE OF THE MATERIAL WILL NOT INFRINGE ANY PATENT, COPYRIGHT, 'TRADEMARK, OR OTHER PROPRIETARY RIGHTS.10. Except to the ex

35、tent prohibited by law, the RECIPIENT assumes all liability for damages which may arise from its use, storage or disposal of the MATERIAL. The PROVIDER will not be liable to the RECIPIENT for any loss, claim or demand made by the RECIPIENT, or made against the RECIPIENT by any other party, due to or

36、 arising from the use of the MATERIAL by the RECIPIENT, except to the extent permitted by law when caused by the gross negligence or willful misconduct of the PROVIDER.11. This agreement shall not be interpreted to prevent or delay publication of research findings resulting from the use of the MATER

37、IAL or the MODIFICATIONS. The RECIPIENT SCIENTIST agrees to provide appropriate acknowledgment of the source of the MA TERIAL in all publications.12. The RECIPIENT agrees to use the MATERIAL in compliance with all applicable statutes and regulations.13. This Agreement will terminate on the earliest

38、of the following dates: (a) when the MA TERIAL becomes generally available from third parties, for example, through reagent catalogs or public depositories, or (b) on completion of the RECIPIENT's current research with the MATERIAL, or (c) on thirty (30) days written notice by either party to th

39、e other, or (d) on the date specified in an implementing letter, provided that:(1) if termination should occur under Section 13(a), the RECIPIENT shall be bound to the PROVIDER by the least restrictive terms applicable to the MATERIAL obtained from the then-available sources; and(2) if termination s

40、hould occur under 13(b) or (d) above, the RECIPIENT will discontinue its use of the MATERIAL and will, upon direction of the PROVIDER, return or destroy any remaining MATERIAL. The RECIPIENT, at its discretion, will also either destroy the MODIFICA TIONS or remain bound by the terms of this agreement as they apply to MODIFICA TIONS;(3) in the event the PROVIDER terminates this Agreement under 13(c) other than for breach of this Agreement