D-minus-Lactic-acid-R-2-Hydroxypropionic-acid-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemED-(-)-Lactic acidCat. No.: HY-111095CAS No.: 10326-41-7Synonyms: (R)-2-Hydroxypropionic acid分式: CHO分量: 90.08作靶點(diǎn): Endogenous Metabolite作通路: Metabolic Enzyme/Protease儲(chǔ)存式: 4C, protect from light* In solvent : -80C, 6 months; -20C,

2、1 month (protect fromlight)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 125 mg/mL (1387.66 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 11.1012 mL 55.5062 mL 111.0124 mL5 mM 2.2202 mL 11.1012 mL 22.2025 mL10 mM 1.1101 mL 5.5506 mL 11.1012 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保

3、存式和期限。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (23.09 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2

4、.08 mg/mL (23.09 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oil1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.08 mg/mL (23.09 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 D-(-)-Lactic acid糖發(fā)酵 (氧化，新成代謝) 的個(gè)中間產(chǎn)物。D-(-)-Lactic acid 在植物中是ProDH (prolinedehydrogenase 1) 的競(jìng)爭(zhēng)性抑制劑。IC50 & T

5、arget Human Endogenous MetaboliteREFERENCES1. Schertl P, et al. Biochemical characterization of proline dehydrogenase in Arabidopsis mitochondria. FEBS J. 2014 Jun;281(12):2794-804.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58955