Licochalcone-A-Licochalcone-A-DataSheet-生命科學試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemELicochalcone ACat. No.: HY-N0372CAS No.: 58749-22-7Synonyms: Licochalcone-A分式: CHO分量: 338.4作靶點: Autophagy作通路: Autophagy儲存式: Powder -20C 3 years4C 2 years* 該產(chǎn)品在溶液狀態(tài)不穩(wěn)定，建議您現(xiàn)現(xiàn)配，即刻使。溶解性數(shù)據(jù)體外實驗 DMSO : 31 mg/mL (91.61 mM)* means solubl

2、e, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.9551 mL 14.7754 mL 29.5508 mL5 mM 0.5910 mL 2.9551 mL 5.9102 mL10 mM 0.2955 mL 1.4775 mL 2.9551 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液；該產(chǎn)品在溶液狀態(tài)不穩(wěn)定，建議您現(xiàn)現(xiàn)配，即刻使。體內(nèi)實驗請根據(jù)您的實驗動物和給藥式選擇適當?shù)娜芙獍福渲魄罢埾扰渲瞥吻宓膬湟?，再依次添加助溶?為保證實驗結(jié)果的可靠性，體內(nèi)實驗的作液，建議

3、您現(xiàn)現(xiàn)配，當天使；澄清的儲備液可以根據(jù)儲存條件，適當保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (7.39 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (7.39 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedC

4、hemE3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (7.39 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 草查爾酮A (Licochalcone A)種黃酮類化合物，具有抗癌功效，對UGT1A1的IC50值為0.97 M。REFERENCES1. Tang ZH, et al. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small ce

5、ll lungcancer cells. Sci Rep. 2016 May 17;6:26241.2. Hong Xin, et al. Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. Food andChemical ToxicologyVolume 90, April 2016, Pages 1121223. Egler J, et al. Licochalcone A Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2015;37(5):2060-70.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;