Flavoxate-hydrochloride-Rec-7-0040-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEFlavoxate hydrochlorideCat. No.: HY-B0549ACAS No.: 3717-88-2Synonyms: Rec-7-0040; DW61分式: CHClNO分量: 427.92作靶點(diǎn): mAChR作通路: GPCR/G Protein; Neuronal Signaling儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性

2、數(shù)據(jù)體外實(shí)驗(yàn) H2O : 5 mg/mL (11.68 mM; Need ultrasonic)DMSO : 3.33 mg/mL (7.78 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.3369 mL 11.6844 mL 23.3689 mL5 mM 0.4674 mL 2.3369 mL 4.6738 mL10 mM 0.2337 mL 1.1684 mL 2.3369 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL AC

3、TIVITY物活性 Flavoxate(DW-61)鹽酸鹽是毒蕈堿受體AChR拮抗劑， IC50為12.2 M。REFERENCES1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE1. Dansette, P.M., M. Jaoen, and C. Pons, HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins. ExpToxicol Pathol, 2000. 52(2): p. 145-8.2. Kimura, Y.

4、, et al., Mechanisms of the suppression of the bladder activity by flavoxate. Int J Urol, 1996. 3(3): p. 218-27.3. Oka, M., et al., Brain pertussis toxin-sensitive G proteins are involved in the flavoxate hydrochloride-induced suppression of themicturition reflex in rats. Brain Res, 1996. 727(1-2): p. 91-8.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: