Pulchinenoside-C-Anemoside-B4-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPulchinenoside CCat. No.: HY-N0205CAS No.: 129741-57-7Synonyms: Anemoside B4分式: CHO分量: 1221.38作靶點(diǎn): Others作通路: Others儲(chǔ)存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect fromlight)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 125

2、mg/mL (102.34 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 0.8187 mL 4.0937 mL 8.1875 mL5 mM 0.1637 mL 0.8187 mL 1.6375 mL10 mM 0.0819 mL 0.4094 mL 0.8187 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您

3、現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (1.70 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (1.70 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubilit

4、y: 2.08 mg/mL (1.70 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 Pulchinenoside C (Anemoside B4)個(gè)天然的頭翁皂苷B4，有很多物效應(yīng)，例如抗腫瘤，神經(jīng)保護(hù)，抗管成等活性。體外研究 Pulchinenoside C (Anemoside B4) can inhibit the secretion of IL-10; SSA, SSD and PNS up-regulated IL-2expression 1. P

5、ulchinenoside C (Anemoside B4), with IC50 value more than 390 ug/mL. Anemoside B4inhibits cell proliferation 2. Pulchinenoside C (Anemoside B4) can significantly suppress the secretion of theinflammatory factor E-selectin by endothelial cells 3.REFERENCES1. Hu Y et al. Role of Chinese herbal medicin

6、al ingredients in secretion of cytokines by PCV2-induced endothelial cells. J Immunotoxicol.2016;13(2):141-7.2. Liu M et al. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinicacid. Pharm Biol. 2015 Jan;53(1):1-9.3. Hu Y et al. Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinalmicrovascular endothelial cells. Immunopharmacol Immunotoxicol. 2009;31(4):550-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use on