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常見腫瘤化療方案常見腫瘤化療方案常見腫瘤化療方案xxx公司常見腫瘤化療方案文件編號(hào):文件日期:修訂次數(shù):第1.0次更改批準(zhǔn)審核制定方案設(shè)計(jì),管理制度常見腫瘤化療方案()一、頭頸部癌1、DDP+5-FuCisplatin100mg/m2.(1hinf)d15-Fluorouracil1000mg/m2.(continf)d1-4(5)3~4周重復(fù),也可用于放療前2、CBP+5-FuCarboplatin300mg/m2.d15-Fluorouracil1000mg/m2.(continf)d1-43~4周重復(fù)3、IPIfosfamide(異環(huán)磷酰胺)1500mg/m2.(Mesna保護(hù))d1-5Cisplatin10mg/m2.(30mininf)d1-54周重復(fù)4、TIPPaclitaxel(紫杉醇)175mg/m2.(3hinf)d1Ifosfamide1000mg/m2.(2h,Mesna保護(hù))d1-3Cisplatin60mg/m2.d13~4周重復(fù)5、TICPaclitaxel175mg/m2.(3hinf)d1Ifosfamide1000mg/m2.(2h,Mesna保護(hù))d1-3CarboplatinAUC=6.(30mininf)d13~4周重復(fù)6、Docetaxel+CisplatinDocetaxel(多西紫杉醇)100mg/m2.(1hinf)d1Cisplatin75mg/m2.(3hinf)d13周重復(fù)7、Docetaxel+Cisplatin+5-Fluororacil(TPF)Docetaxel75mg/m2.d1Cisplatin100mg/m2.d15-Fluorouracil1000mg/m2.(continf)d1-43周重復(fù)8、PBFCisplatin100mg/m2.(1hinf)d1Bleomycin(博來霉素)15mg.(bolus)d1followedby16mg/m2.(continf)d1-55-Fluorouracil650mg/m2.(continf)d1-54周重復(fù)9、BECCisplatin100mg/m2.(1hinf)d1Epirubicin(表柔比星)70mg/m2.(bolus)d1Bleomycin15mg.(bolus)d1followedby12mg/m2.(continf)d1-54周重復(fù)二、乳腺癌1、經(jīng)典CMFCyclophosphamide(環(huán)磷酰胺)100mg/m2.d1-14Methotrexate(氨甲喋呤)40mg/m2.d1,85-Fluorouracil600mg/m2.d1,84周重復(fù)2、改良CMFCyclophosphamide600mg/m2.d1Methotrexate40mg/m2.d15-Fluorouracil600mg/m2.d13周重復(fù)3、ACDoxorubicin(阿霉素(化療藥物))60mg/m2.d1Cyclophosphamide600mg/m2.d1(,8)3周重復(fù)4、ECEpirubicin60mg/m2.d1Cyclophosphamide600mg/m2.d13周重復(fù)5、IEIfosfamide2000mg/m2.(Mesna保護(hù))d1,8Epirubicin30mg/m2.d1,83周重復(fù)6、AC+TDoxorubicin60mg/m2.d1Cyclophosphamide600mg/m2.d13周重復(fù),共4周期,然后Paclitaxel175mg/m2.(3hinf)d13周重復(fù),共4周期7、CAFCyclophosphamide500mg/m2.d1Doxorubicin50mg/m2.d15-Fluorouracil500mg/m2.d13周重復(fù)8、CEFCyclophosphamide500mg/m2.d1Epirubicin100mg/m2.d15-Fluorouracil500mg/m2.d13周重復(fù)9、Paclitaxel單藥Paclitaxel175或200mg/m2.(3hinf)d13周重復(fù)10、TADoxorubicin50mg/m2.d1Paclitaxel220mg/m2.(3hinf)d2(ADM后24h)3周重復(fù)11、Docetaxel單藥Docetaxel75或100mg/m2.(1hinf)d13周重復(fù)或者Docetaxel40mg/m2.(1hinf)qw*4/6w3周重復(fù)12、Docetaxel+DoxorubicinDoxorubicin50mg/m2.d1Docetaxel75mg/m2.(1hinf)d13周重復(fù)13、Vinorelbine+DoxorubicinDoxorubicin40-50mg/m2.d1Vinorelbine20-25mg/m2.d1,83周重復(fù)14、Capecitabine單藥Capecitabine2510mg/m2.分兩次/天,d1-143周重復(fù)15、Trastuzumab單藥Trastuzumab4mg/kg.(90mininf)負(fù)荷量2mg/kg.(30mininf)維持量,qw三、肺癌(一)小細(xì)胞肺癌的化療(SCLC)1、CAOCyclophosphamide1000mg/m2.d1Doxorubicin(阿奇霉素)50mg/m2.d1Vincristine2mg.d13周重復(fù)2、CEVCyclophosphamide1000mg/m2.d1Epirubicin70mg/m2.d1Vincristine2mg.d13周重復(fù)3、EPCisplatin80mg/m2.(1hinf)d1Etoposide100mg/m2.(2hinf)d1-33周重復(fù)4、ECCarboplatin300mg/m2.d1Etoposide120mg/m2.(2hinf)d1-34周重復(fù)5、CAECyclophosphamide1000mg/m2.d1Doxorubicin40-50mg/m2.d1Etoposide100-120mg/m2.(1hinf)d1-33周重復(fù)6、VIPEtoposide75mg/m2.d1-4Ifosfamide1200mg/m2.(Mesna保護(hù))d1-4Cisplatin20mg/m2.d1-43周重復(fù)7、Topotecan單藥Topotecanm2.(30mininf)d1-53周重復(fù)8、Paclitaxel+CarboplatinPaclitaxel175mg/m2.(3hinf)d1CarboplatinAUC=7.(30mininf)d13周重復(fù)(二)非小細(xì)胞肺癌的化療(NSCLC)1、Docetaxel單藥Docetaxel75mg/m2.(1hinf)d13周重復(fù)2、Gemcitabine單藥Gemcitabine1000-1250mg/m2.(30mininf)d1,8,154周重復(fù)3、Vinorelbine單藥Vinorelbine30mg/m2.(20mininf)d1,8,154周重復(fù)4、NPVinorelbine25mg/m2.d1,8,15Cisplatin100mg/m2.d14周重復(fù)5、Paclitaxel+CisplatinPaclitaxel175mg/m2.(3hinf)d1Cisplatin80mg/m2.(1hinf)d13周重復(fù)6、Paclitaxel+CarboplatinPaclitaxel225mg/m2.(3hinf)d1CarboplatinAUC=6.d13周重復(fù)7、Docetaxel+CisplatinDocetaxel75mg/m2.d1Cisplatin75mg/m2.d13周重復(fù)8、Gemcitabine+CisplatinGemcitabine1000mg/m2.(30-60mininf)d1,8,15Cisplatin100mg/m2.(30-60mininf)d14周重復(fù)9、EPCisplatin100mg/m2.(30-60mininf)d1Etoposide100mg/m2.(2hinf)d1-33周重復(fù)四、食管癌1、DDP+5-FuCisplatin100mg/m2.(2hinf)d15-Fluorouracil1000mg/m2.(continf)d1-53~4周重復(fù)2、Paclitaxel+CisptatinPaclitaxel180mg/m2.(3hinf)d1Cisplatin60mg/m2.(3hinf)d13周重復(fù)3、TPEPaclitaxel50mg/m2.(1hinf)d1,4Cisplatin15mg/m2.(1hinf)d1,4Etoposide50mg/m2.(continf)d1,4QW*3,休息1周,4周一療程4、ECFEpirubicin50mg/m2.d1Cisplatin60mg/m2.d15-Fluorouracil200mg/m2.(continf)d1-213周重復(fù)五、胃癌1、5-Fu+CF+DDPCisplatin50mg/m2.(1hinf)biwFolinicacid500mg/m2.(2hinf)qw*65-Fluorouracil2000mg/m2.(24hinf)qw*62、ECFEpirubicin50mg/m2.d1Cisplatin60mg/m2.d15-Fluorouracil200mg/m2.(continf)d1-213周重復(fù)3、FAMTXMethotrexate1~1.5g/m2.d15-Fluorouracil1500mg/m2.d1Doxorubicin30mg/m2.d15Folinicacid15mg/m2.MTX后24h,q6h*124周重復(fù)4、ELFEtoposide120mg/m2.(50mininf)d1-3Folinicacid300mg/m2.(10mininf)d1-35-Fluorouracil500mg/m2.(10mininf)d1-33~4周重復(fù)5、TCDocetaxel85mg/m2.(1hinf)d1Cisplatin75mg/m2.(1hinf)d13周重復(fù)六、大腸癌1、MayoClinicFolinicacid20mg/m2.(bolus)d1-55-Fluorouracil425mg/m2.(bolus)d1-54周重復(fù)2、deGramontFolinicacid200mg/m2.(2hinf)d1-25-Fluorouracil400mg/m2.(bolus)d1-2600mg/m2.(22hinf)d1-22周重復(fù)3、IrinotecanMonotherapyIrinotecan125mg/m2.(90mininf)qw*46周重復(fù)或者Irinotecan300-350mg/m2.(90mininf)d13周重復(fù)4、FOLFORIIrinotecan125mg/m2.(90mininf)qw*4Folinicacid20mg/m2.(bolus)qw*45-Fluorouracil500mg/m2.(bolus)qw*46周重復(fù)或者Irinotecan180mg/m2.(90mininf)d1Folinicacid200mg/m2.(2hinf)d1-25-Fluorouracil400mg/m2.(bolus)d1-2600mg/m2.(22hinf)d1-22周重復(fù)5、Irinotecan+OxaliplatinIrinotecan200mg/m2.(30mininf)d1Oxaliplatin85mg/m2.(2hinf)d13周重復(fù)6、OxaliplatinMonotherapyOxaliplatin130mg/m2.(2hinf)d13周重復(fù)7、FOLFOX4Oxaliplatin85mg/m2.(2hinf)d1Folinicacid200mg/m2.(2hinf)d1-25-Fluorouracil400mg/m2.(bolus)d1-2600mg/m2.(22hinf)d1-22周重復(fù)8、FOLFOX6Oxaliplatin100mg/m2.(2hinf)d1Folinicacid400mg/m2.(2hinf)d15-Fluorouracil400mg/m2.(bolus)d1-22400~3000mg/m2.(46hinf)d1-22周重復(fù)9、RaltitrexedRaltitrexed3mg/m2.d13周重復(fù)10、CapecitabineCapecitabine1250mg/m2.bid*143周重復(fù)11、UFT+CFUFT100mg/m2.tid*28Folinicacid30mg/m2.tid*285周重復(fù)七、胰腺癌1、GemcitabineGemcitabine1000mg/m2.(30mininf)qw*7;休息1周后每周1次,連用3周,4周一療程2、5-Fluorouracil5-Fluorouracil500mg/m2.(bolus)d1-54周重復(fù)3、CF+5-FuFolinicacid20mg/m2.(2hinf)d1-55-Fluorouracil425mg/m2.(bolus)d1-54周重復(fù)4、Gemcitabine+CF+5-FuGemcitabine1000mg/m2.(30mininf)d1,8,15,22Folinicacid200mg/m2.(2hinf)d1,8,15,225-Fluorouracil750mg/m2.(continf)d1,8,15,226周重復(fù)八、膽管癌1、5-Fluorouracil5-Fluorouracil500mg/m2.d1-54周重復(fù)或者5-Fluorouracil600mg/m2.d1,8,154周重復(fù)2、GemcitabineGemcitabine1000mg/m2.(30mininf)d1,8,154周重復(fù)3、GemcitabineGemcitabine2200mg/m2.(30mininf)d12周重復(fù)4、DocetaxelDocetaxel100mg/m2.(1hinf)d13周重復(fù)5、FLMFolinicacid200mg/m2.d1-45-Fluorouracil400mg/m2.d1-4Mitomycin8mg/m2.d14周重復(fù)6、5-Fu+IFN-a5-Fluorouracil750mg/m2.(continf)d1-5Interferonalpha5*106IU.d1,3,52周重復(fù)九、宮頸癌1、IPIfosfamide5000mg/m2.(24hinf,Mesna保護(hù))d1Cisplatin50mg/m2.d13周重復(fù)2、ICIfosfamide5000mg/m2.(24hinf,Mesna保護(hù))d1Carboplatin300mg/m2.d14周重復(fù)3、BIPBleomycin30mg/m2.(24hinf)d1Ifosfamide5000mg/m2.(24hinf,Mesna保護(hù))d2Cisplatin50mg/m2.d24周重復(fù)4、TIPPaclitaxel175mg/m2.(3hinf)d1Ifosfamide5000mg/m2.(24hinf,Mesna保護(hù))d2Cisplatin50mg/m2.d24周重復(fù)5、TPPaclitaxel135mg/m2.(24hinf)d1Cisplatin50~75mg/m2.d23周重復(fù)6、PFCisplatin75mg/m2.d15-Fluorouracil1000mg/m2.(continf)d1-43周重復(fù),也可同時(shí)合并放療十、子宮內(nèi)膜癌1、APDoxorubicin60mg/m2.d1Cisplatin50~60mg/m2.d13周重復(fù)2、TCPaclitaxel175mg/m2.(3hinf)d1CarboplatinAUC=5~7.(30mininf)d13周重復(fù)3、PCDDoxorubicin45mg/m2.d1Paclitaxel160mg/m2.(3hinf)d1Cisplatin60mg/m2.(1hinf)d13周重復(fù),G-CSF支持十一、卵巢癌一線化療1、TPPaclitaxel135mg/m2.(3h或24hinf)d1Cisplatin75mg/m2.(1mg/min)d1或d23周重復(fù)2、TCPaclitaxel175mg/m2.(3hinf)d1CarboplatinAUC=5~6.(1hinf)d13周重復(fù)3、CBP+CTXCyclophosphamide600mg/m2.d1Carboplatin300mg/m2.(1hinf)d14周重復(fù)挽救治療1、TopotecanTopotecan~m2.(30mininf)d1-53周重復(fù)2、EtoposideEtoposide50~100mg/m2.d1-143周重復(fù)3、GemcitabineGemcitabine800~1250mg/m2.(30mininf)d1,8,154周重復(fù)4、IfosfamideIfosfamide1200~2400mg/m2.(30min~2hinf,Mesna保護(hù))d1-53~4周重復(fù)或者Ifosfamide1000mg/m2.(coninf,Mesna保護(hù))d1-74周重復(fù)5、IPIfosfamide1500mg/m2.(1hinf,Mesna保護(hù))d2-5Paclitaxel175mg/m2.(3hinf)d13周重復(fù)6、IMIfosfamide2000mg/m2.(30mininf,Mesna保護(hù))d1-3Mitoxantrone10mg/m2.(30mininf)d13~4周重復(fù)7、脂質(zhì)體ADM脂質(zhì)體ADM50mg/m2.(1hinf)d14周重復(fù)十二、絨毛膜癌低危1、MethorexateMethorexate~kg.或.(bolus)d1-5周重復(fù)2、DactinomycinDactinomycin10~12ug/kg.(bolus)d1-5周重復(fù)高危1、EMA-COEtoposide100mg/m2.(1hinf)d1-2Methorexate100mg/m2.d1200mg/m2.(12hinf)d1Dactinomycinm2.(bolus)d1-2Cyclophosphamide600mg/m2.(30mininf)d8Vincristinem2.(bolus)d83周重復(fù)2、MACMethorexatekg.d1-5Dactinomycin8~10ug/kg.(bolus)d1-5Cyclophosphamide250mg.(bolus)d1-5Chlorambucilkg.d1-52~3周重復(fù)3周重復(fù)3、挽救治療低危1、EAEtoposide100mg/m2.(1hinf)d1-3Dactinomycinm2.(bolus)d1-310天重復(fù)高危1、EP/EMAEPEtoposide150mg/m2.(30mininf)d1Cisplatin75mg/m2.(4hinf)d1EMAEtoposide100mg/m2.(30mininf)d1Methorexate300mg/m2.(12hinf)d1Dactinomycin.(bolus)d1Folinicacid15mgbid,.或.(MTX后24h,q6h*4)d2,3EP/EMA每周交替十三、生殖細(xì)胞惡性腫瘤(一)非精原細(xì)胞瘤1、BEPBleomycin30mg/m2.(bolus)d1,8,15Etoposide100mg/m2.(1hinf)d1-5或165mg/m2.(1hinf)d1-3Cisplatin50mg/m2.d1-2或20mg/m2.d1-53周重復(fù)2、ACEDactinomycin.(bolus)d1-3Cyclophosphamide500mg/m2.(30mininf)d3Etoposide100mg/m2.(1hinf)d1-34周重復(fù)3、VIPEtoposide200mg/m2.(1hinf)d1-5Ifosfamide1600mg/m2.(1hinf,Mesna保護(hù))d1-5Cisplatin30mg/m2.(1hinf)d1-53周重復(fù),G-CSF支持4、T-BEPPaclitaxel175mg/m2.(1hinf)d1Bleomycin30mg.(bolus)d1,8,15Etoposide200mg/m2.(1hinf)d1-5Cisplatin30mg/m2.(1hinf)d1-53周重復(fù),G-CSF支持5、VeIPVinblastinekg.(bolus)d1-2Ifosfamide1200mg/m2.(1hinf,Mesna保護(hù))d1~5Cisplatin20mg/m2.(30mininf)d1~53周重復(fù)6、TIPPaclitaxel250mg/m2.(24hinf)d1Ifosfamide1200mg/m2.(1hinf,Mesna保護(hù))d2-6Cisplatin20mg/m2.(30mininf)d2-63周重復(fù),G-CSF支持(二)精原細(xì)胞瘤EP1、BEPEtoposide100mg/m2.(1hinf)d1-5Cisplatin20mg/m2.(30mininf)d1-53周重復(fù)2、VeIPVinblastinekg.(bolus)d1-2Ifosfamide1200mg/m2.(1hinf,Mesna保護(hù))d1~5Cisplatin20mg/m2.(30mininf)d1~53周重復(fù)十四、原發(fā)不明轉(zhuǎn)移瘤1、TCEPaclitaxel200mg/m2.(1hinf)d1CarboplatinAUC=6.(20~30mininf)d1Etoposide50mg.d1,3,5,7,9100mg.d2,4,6,8,103周重復(fù)2、PEBBleomycin30mg.(bolus)d1,8,15Etoposide100mg/m2.(1hinf)d1-5Cisplatin20mg/m2.d1~53周重復(fù)3、DCDocetaxel65mg/m2.d1CarboplatinAUC=6.d13周重復(fù)4、TFLPaclitaxel175mg/m2.(3hinf)d1Folinicacid300mg.(30~60mininf)d1-35-Fluorouracil350mg/m2.(30~60mininf)d1-34周重復(fù)5、VACVinblastinem2.d1Doxorubicin50mg/m2.d1Cyclophosphamide500mg/m2.d13周重復(fù)十五、惡性黑色素瘤1、DacarbazineDacarbazine850~1000mg/m2.d1或者250mg/m2.d1-53~4周重復(fù)2、FotemustineFotemustine100mg/m2.(1hinf)d1,8,153周重復(fù)3、VindesineVinblastine3mg/m2.d12周重復(fù),共1年;然后3周重復(fù),共6月;最后4周重復(fù),共6月4、低劑量IFNInterferonalpha3MU月5、中劑量IFNInterferonalpha10MU天/周4周;然后5MU年6、高劑量IFNInterferonalpha20MU/m2.或5天/周4周;然后10MU/m2周7、Interleukin-2Interleukin-2600000或720000IU/kg.(15min)每8小時(shí)一次,共14次,2周重復(fù);若耐受,6~12周為一療程,最多5療程8、Dartmouth方案Cisplatin25mg/m2.(30~45mininf)d1-3BCNU150mg/m2.(shortinf)d1Dacarbazine220mg/m2.(shortinf)d1-3Tamoxifen20~40mg.化療前1周開始3周重復(fù)9、DVPDacarbazine250mg/m2.(30mininf)d1-5Vindesine3mg/m2.(bolus)d1,8,15Cisplatin100mg/m2.(30mininf)d14周重復(fù)10、Dacarbazine+InterferonalphaDacarbazine800mg/m2.(shortinf)d1Interferonalpha9MU周重復(fù)11、Dacarbazine+Cisplatin+Interferonalpha+Interleukin-2Dacarbazine250mg/m2.(30mininf)d1-3Cisplatin25mg/m2.(1hinf)d1-3Interferonalpha5MU/m2.d6,8,10,13,15Interleukin-218MU/m2.(15mininf)d6-10,13-154周重復(fù)十六、惡性間皮瘤1、EpirubicinEpirubicin110mg/m2.(bolus)d13周重復(fù)2、VinorelbineVinorelbine30mg/m2.(5mininf)qw6周為一療程3、APDoxorubicin60mg/m2.(bolus)d1Cisplatin60mg/m2.(1hinf)d13~4周重復(fù)4、GPGemcitabine1000mg/m2.(30mininf)d1,8,15Cisplatin100mg/m2.(2hinf)d14周重復(fù)十七、神經(jīng)內(nèi)分泌癌1、DoxorubicinDoxorubicin60mg/m2.(bolus)d13~4周重復(fù)2、5-Fluorouracil5-Fluorouracil500mg/m2.(bolus)d1-55周重復(fù)3、EPEtoposide130mg/m2.(24hinf)d1-3Cisplatin45mg/m2.(24hinf)d2-34周重復(fù)4、CVDCyclophosphamide750mg/m2.(bolus)d1Vincristinem2.(bolus)d1Dacarbazine600mg/m2.(bolus)d13~4周重復(fù)5、EAPDoxorubicin20mg/m2.(bolus)d1,8Etoposide100mg/m2.(1hinf)d5-7Cisplatin40mg/m2.(1hinf)d2,94周重復(fù)4、EDF5-Fluorouracil500mg/m2.d1-3Dacarbazine200mg/m2.(30mininf)d1Etoposide30mg/m2.d1-33周重復(fù)十八、軟組織肉瘤1、IAIfosfamide5000mg/m2.(24hinf,Mesna保護(hù))d1Doxorubicin50~75mg/m2.(shortinf)d13周重復(fù)或者Ifosfamide2000mg/m2.(24hinf,Mesna保護(hù))d1-5Doxorubicin25mg/m2.(continf)d1-33周重復(fù)2、IEIfosfamide1800mg/m2.(1hinf,Mesna保護(hù))d1-5Epirubicin60mg/m2.(shortinf)d1-23周重復(fù)3、MAIDIfosfamide2000~2500mg/m2/d.(continf,Mesna保護(hù))d1-3Doxorubicin15mg/m2/d.(continf)d1-4Dacarbazine250mg/m2/d.(continf)d1-43周重復(fù)4、IVAIfosfamide3000mg/m2.(Mesna保護(hù))d1-2Dactinomycinm2(max2mg).d1Vincristinem2(max2mg).d1,8,153~4周重復(fù)5、APDoxorubicin60mg/m2.d1Cisplatin100mg/m2.d13~4周重復(fù)十九、胸腺瘤1、CAPCyclophosphamide500mg/m2.(bolus)d1Doxorubicin50mg/m2.(bolus)d1Cisplatin50mg/m2.(1hinf)d13周重復(fù)2、ADOCCyclophosphamide700mg/m2.(bolus)d4Doxorubicin40mg/m2.(bolus)d1Cisplatin50mg/m2.(1hinf)d1Vincristinem2.(bolus)d23周重復(fù)3、EPEtoposide120mg/m2.(30mininf)d1-3Cisplatin60mg/m2.(1hinf)d13周重復(fù)4、IfosfamideIfosfamide1500mg/m2.(30mininf,Mesna保護(hù))d1-55、BEPBleomycin30mg/m2.(bolus)d1,8,15Etoposide100mg/m2.(1hinf)d1-5Cisplatin50mg/m2.d1-23周重復(fù)二十、膀胱癌1、MVACMethotrexate30mg/m2.(bolus)d1,15,22Vinblastine3mg/m2.(bolus)d1,15,22Doxorubicin30mg/m2.(bolus)d1Cisplatin70mg/m2.(1~2hinf)d24~5周重復(fù)2、GPGemcitabine1000mg/m2.(30~60mininf)d1,8,15Cisplatin70mg/m2.(60mininf)d24周重復(fù)3、Paclitaxel+CisplatinPaclitaxel175mg/m2.(3hinf)d1Cisplatin75mg/m2.(1hinf)d13周重復(fù)4、CMVMethotrexate30mg/m2.(bolus)d1,8Vinblastine4mg/m2.(bolus)d1,8Cisplatin70~100mg/m2.(1hinf)d23周重復(fù)5、ITPPaclitaxel200mg/m2.(3hinf)d1Cisplatin70mg/m2.(1hinf)d1Ifosfamide1500mg/m2.(1hinf,Mesna保護(hù))d1-33~4周重復(fù),G-CSF支持二十一、多發(fā)性骨髓瘤1、MPMelphalankg/d.d1-4Prednisone100mg/d.d1-44周重復(fù)2、M2Vincristinem2.d1BCNU20mg/m2.d1Melphalan8mg/m2.d1-4Cyclophosphamide400mg/m2.d1Prednisone100mg/d.d1-45周重復(fù)3、Thalidomide+DexamethasoneThalidomide200mg/d.d1-28Dexamethasone40mg/d.d1-4,9-12,17-203周重復(fù)二十二、惡性淋巴瘤(一)霍奇金淋巴瘤1、MOPPNitrogenmustard6mg/m2.d1Vincristinem2(max2mg).d1Procarbazine100mg/m2.d1-14Prednisone40mg/m2.d1-144周重復(fù)2、ABVDDoxorubicin25mg/m2.d1,15Bleomycin10mg/m2.d1,15Vinblastine6mg/m2.d1,15Dacarbazine375mg/m2.d1,154周重復(fù)3、ChlVPPCB13486mg/m2.d1-14Vinblastine6mg/m2.d1,8Procarbazine100mg/m2.d1-14Prednisone40mg/m2.d1-144周重復(fù)4、B-CAVEBleomycin5mg/m2.d1,8,15CCNU100mg/m2.d1Doxorubicin60mg/m2.d1Vinblastine5mg/m2.d14周重復(fù)5、CVBBleomycin15mg/m2.d1,8CCNU100mg/m2.d1Vinblastine6mg/m2.d1,84周重復(fù)挽救方案1、EVAEtoposide100mg/m2.d1-3Doxorubicin50mg/m2.d1Vinblastine6mg/m2.d14周重復(fù)2、BEAMBCNU60mg/m2.(30mininf)d1Etoposide75mg/m2.d2-5Cytarabine100mg/m2bid,.(30mininf)d2-5Melphalan30mg/m2.d64周重復(fù)3、ASHAPDoxorubicin10mg/m2.(continf)d1-4Cisplatin25mg/m2.(continf)d1-4Cytarabine1500mg/m2.(2hinf)d5Methylprednisolone500mg/m2.(15mininf)d1-54周重復(fù)(二)非霍奇金淋巴瘤1、COPPCyclophosphamide650mg/m2.d1,8Vincristinem2(max2mg).d1,8Procarbazine100mg/m2.d1-14Prednisone40mg/m2.d1-144周重復(fù)2、COMPCyclophosphamide400mg/m2.d1,8Vincristinem2(max2mg).d1,8Methetrexate25mg/m2.d1,8Prednisone30mg/m2.d1-144周重復(fù)3、CHOPCyclophosphamide750mg/m2.d1Vinc
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