骨質(zhì)疏松癥課件整理-002

骨質(zhì)疏松癥骨質(zhì)疏松癥1目錄頁01疾病概述02發(fā)病機(jī)制Contents03臨床表現(xiàn)Page04診斷與鑒別診斷05預(yù)防及治療目錄頁2過渡頁0疾病概述Transition●定義●分類Page●流行病學(xué)過渡頁0疾病概述3疾病概述11骨質(zhì)疏松癥的定義■定義WHO(世界衛(wèi)生組織,1994)骨質(zhì)疏松癥(Osteoporosis,OP)是種以骨量低下,骨微結(jié)構(gòu)損壞,導(dǎo)致骨脆性增加,易發(fā)牛骨折為特征的全身性骨病■定義NIH(美國國立衛(wèi)生研究院2019)正常骨骼骨質(zhì)疏松癥的骨骼骨質(zhì)巰松癥是以骨強(qiáng)度下降、骨折風(fēng)險(xiǎn)性增加為特征的骨骼系統(tǒng)疾病1.Osteoporosisprevention,diagnosis,andtherapy.JAMA.2019:285:785-7952.Thediagnosisofosteoporosis()JBoneMinerRes,1994,9:1137-1140疾病概述4疾病概述12骨質(zhì)疏松癥的分類①絕經(jīng)后骨質(zhì)疏松癥(I型):由任何影響骨代謝的疾病和/原發(fā)型)發(fā)生在婦女電后內(nèi)(繼發(fā)型成藥機(jī)導(dǎo)的骨質(zhì)松骨質(zhì)疏松/②老年骨質(zhì)疏松癥(Ⅱ型):骨質(zhì)疏松常見的有:糖皮質(zhì)激柰引起的骨一股指70歲后發(fā)生的骨質(zhì)疏松質(zhì)硫松(GOP),原發(fā)性甲狀旁腺Q(mào)特發(fā)性骨質(zhì)疏松癥:包括青少年型功能亢進(jìn)引起的骨質(zhì)疏松等L中華醫(yī)學(xué)會(huì)骨質(zhì)疏私和骨礦鹽疾病分會(huì),原發(fā)性骨質(zhì)松癥診治指南(20年,中華骨質(zhì)岍松和骨礦鹽病雜志,20194:2-17疾病概述5骨質(zhì)疏松癥課件整理_0026骨質(zhì)疏松癥課件整理_0027骨質(zhì)疏松癥課件整理_0028骨質(zhì)疏松癥課件整理_0029骨質(zhì)疏松癥課件整理_00210骨質(zhì)疏松癥課件整理_00211骨質(zhì)疏松癥課件整理_00212骨質(zhì)疏松癥課件整理_00213骨質(zhì)疏松癥課件整理_00214骨質(zhì)疏松癥課件整理_00215骨質(zhì)疏松癥課件整理_00216骨質(zhì)疏松癥課件整理_00217骨質(zhì)疏松癥課件整理_00218骨質(zhì)疏松癥課件整理_00219骨質(zhì)疏松癥課件整理_00220骨質(zhì)疏松癥課件整理_00221骨質(zhì)疏松癥課件整理_00222骨質(zhì)疏松癥課件整理_00223骨質(zhì)疏松癥課件整理_00224骨質(zhì)疏松癥課件整理_00225骨質(zhì)疏松癥課件整理_00226骨質(zhì)疏松癥課件整理_00227骨質(zhì)疏松癥課件整理_00228骨質(zhì)疏松癥課件整理_00229骨質(zhì)疏松癥課件整理_00230骨質(zhì)疏松癥課件整理_00231骨質(zhì)疏松癥課件整理_00232骨質(zhì)疏松癥課件整理_00233骨質(zhì)疏松癥課件整理_00234骨質(zhì)疏松癥課件整理_00235骨質(zhì)疏松癥課件整理_00236骨質(zhì)疏松癥課件整理_00237骨質(zhì)疏松癥課件整理_00238骨質(zhì)疏松癥課件整理_00239骨質(zhì)疏松癥課件整理_00240骨質(zhì)疏松癥課件整理_00241骨質(zhì)疏松癥課件整理_00242骨質(zhì)疏松癥課件整理_00243骨質(zhì)疏松癥課件整理_00244骨質(zhì)疏松癥課件整理_00245骨質(zhì)疏松癥課件整理_00246骨質(zhì)疏松癥課件整理_00247骨質(zhì)疏松癥課件整理_00248骨質(zhì)疏松癥課件整理_00249骨質(zhì)疏松癥課件整理_00250骨質(zhì)疏松癥課件整理_00251骨質(zhì)疏松癥課件整理_00252骨質(zhì)疏松癥課件整理_00253骨質(zhì)疏松癥課件整理_00254骨質(zhì)疏松癥課件整理_00255骨質(zhì)疏松癥課件整理_00256骨質(zhì)疏松癥課件整理_00257骨質(zhì)疏松癥課件整理_00258骨質(zhì)疏松癥課件整理_00259骨質(zhì)疏松癥課件整理_00260骨質(zhì)疏松癥課件整理_00261骨質(zhì)疏松癥骨質(zhì)疏松癥62目錄頁01疾病概述02發(fā)病機(jī)制Contents03臨床表現(xiàn)Page04診斷與鑒別診斷05預(yù)防及治療目錄頁63過渡頁0疾病概述Transition●定義●分類Page●流行病學(xué)過渡頁0疾病概述64疾病概述11骨質(zhì)疏松癥的定義■定義WHO(世界衛(wèi)生組織,1994)骨質(zhì)疏松癥(Osteoporosis,OP)是種以骨量低下,骨微結(jié)構(gòu)損壞,導(dǎo)致骨脆性增加,易發(fā)牛骨折為特征的全身性骨病■定義NIH(美國國立衛(wèi)生研究院2019)正常骨骼骨質(zhì)疏松癥的骨骼骨質(zhì)巰松癥是以骨強(qiáng)度下降、骨折風(fēng)險(xiǎn)性增加為特征的骨骼系統(tǒng)疾病1.Osteoporosisprevention,diagnosis,andtherapy.JAMA.2019:285:785-7952.Thediagnosisofosteoporosis()JBoneMinerRes,1994,9:1137-1140疾病概述65疾病概述12骨質(zhì)疏松癥的分類①絕經(jīng)后骨質(zhì)疏松癥(I型):由任何影響骨代謝的疾病和/原發(fā)型)發(fā)生在婦女電后內(nèi)(繼發(fā)型成藥機(jī)導(dǎo)的骨質(zhì)松骨質(zhì)疏松/②老年骨質(zhì)疏松癥(Ⅱ型):骨質(zhì)疏松常見的有:糖皮質(zhì)激柰引起的骨一股指70歲后發(fā)生的骨質(zhì)疏松質(zhì)硫松(GOP),原發(fā)性甲狀旁腺Q(mào)特發(fā)性骨質(zhì)疏松癥:包括青少年型功能亢進(jìn)引起的骨質(zhì)疏松等L中華醫(yī)學(xué)會(huì)骨質(zhì)疏私和骨礦鹽疾病分會(huì),原發(fā)性骨質(zhì)松癥診治指南(20年,中華骨質(zhì)岍松和骨礦鹽病雜志,20194:2-17疾病概述66骨質(zhì)疏松癥課件整理_00267骨質(zhì)疏松癥課件整理_00268骨質(zhì)疏松癥課件整理_00269骨質(zhì)疏松癥課件整理_00270骨質(zhì)疏松癥課件整理_00271骨質(zhì)疏松癥課件整理_00272骨質(zhì)疏松癥課件整理_00273骨質(zhì)疏松癥課件整理_00274骨質(zhì)疏松癥課件整理_00275骨質(zhì)疏松癥課件整理_00276骨質(zhì)疏松癥課件整理_00277骨質(zhì)疏松癥課件整理_00278骨質(zhì)疏松癥課件整理_00279骨質(zhì)疏松癥課件整理_00280骨質(zhì)疏松癥課件整理_00281骨質(zhì)疏松癥課件整理_00282骨質(zhì)疏松癥課件整理_00283骨質(zhì)疏松癥課件整理_00284骨質(zhì)疏松癥課件整理_00285骨質(zhì)疏松癥課件整理_00286骨質(zhì)疏松癥課件整理_00287骨質(zhì)疏松癥課件整理_00288骨質(zhì)疏松癥課件整理_00289骨質(zhì)疏松癥課件整理_00290骨質(zhì)疏松癥課件整理_00291骨質(zhì)疏松癥課件整理_00292骨質(zhì)疏松癥課件整理_00293骨質(zhì)疏松癥課件整理_00294骨質(zhì)疏松癥課件整理_00295骨質(zhì)疏松癥課件整理_00296骨質(zhì)疏松癥課件整理_00297骨質(zhì)疏松癥課件整理_00298骨質(zhì)疏松癥課件整理_00299骨質(zhì)疏松癥課件整理_002100骨質(zhì)疏松癥課件整理_002101骨質(zhì)疏松癥課件整理_002102骨質(zhì)疏松癥課件整理_002103骨質(zhì)疏松癥課件整理_002104骨質(zhì)疏松癥課件整理_002105骨質(zhì)疏松癥課件整理_002106骨質(zhì)疏松癥課件整理_002107骨質(zhì)疏松癥課件整理_002108骨質(zhì)疏松癥課件整理_002109骨質(zhì)疏松癥課件整理_002110骨質(zhì)疏松癥課件整理_002111骨質(zhì)疏松癥課件整理_002112骨質(zhì)疏松癥課件整理_0021