三蟲(chóng)半夏白術(shù)天麻湯治療風(fēng)痰瘀阻型急性缺血性腦卒中患者的臨床療效觀察_第1頁(yè)
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三蟲(chóng)半夏白術(shù)天麻湯治療風(fēng)痰瘀阻型急性缺血性腦卒中患者的臨床療效觀察摘要:目的:觀察三蟲(chóng)半夏白術(shù)天麻湯治療風(fēng)痰瘀阻型急性缺血性腦卒中患者的臨床療效。

方法:選取2019年1月至2021年1月在我院神經(jīng)內(nèi)科收治的風(fēng)痰瘀阻型急性缺血性腦卒中患者60例,隨機(jī)分為治療組和對(duì)照組,每組30例。治療組給予三蟲(chóng)半夏白術(shù)天麻湯治療,對(duì)照組給予常規(guī)處理,兩組均給予慢性病藥物治療,并對(duì)兩組患者進(jìn)行療效觀察,分別在治療前、治療后1個(gè)月進(jìn)行神經(jīng)功能評(píng)估、CT或MRI檢查等。

結(jié)果:治療組患者治療后神經(jīng)功能評(píng)分明顯高于對(duì)照組(P<0.05);治療組患者腦梗死面積顯著縮小(P<0.05),腦梗死復(fù)發(fā)率低于對(duì)照組(P<0.05)。

結(jié)論:三蟲(chóng)半夏白術(shù)天麻湯在治療風(fēng)痰瘀阻型急性缺血性腦卒中方面具有顯著療效,值得進(jìn)一步推廣使用。

關(guān)鍵詞:三蟲(chóng)半夏白術(shù)天麻湯;風(fēng)痰瘀阻型急性缺血性腦卒中;臨床療效觀察

Abstract:Objective:ToobservetheclinicalefficacyofSanChongBanXiaBaiZhuTianMaTanginthetreatmentofwindphlegmstasisobstructiontypeacuteischemicstroke.

Methods:SixtypatientswithwindphlegmstasisobstructiontypeacuteischemicstrokewhowereadmittedtotheNeurologyDepartmentofourhospitalfromJanuary2019toJanuary2021wererandomlydividedintothetreatmentgroupandthecontrolgroup,with30casesineachgroup.ThetreatmentgroupwastreatedwithSanChongBanXiaBaiZhuTianMaTang,andthecontrolgroupwastreatedwithroutinetreatment.Bothgroupsweretreatedwithchronicdiseasemedication,andtheefficacyofthetwogroupsofpatientswasobserved,andneurologicalfunctionassessment,CTorMRIexaminationwereperformedbeforeand1monthaftertreatment.

Results:Theneurologicalfunctionscoresofpatientsinthetreatmentgroupweresignificantlyhigherthanthoseinthecontrolgroupaftertreatment(P<0.05);theinfarctionareaofpatientsinthetreatmentgroupwassignificantlyreduced(P<0.05),andtherecurrencerateofinfarctionwaslowerthanthatinthecontrolgroup(P<0.05).

Conclusion:SanChongBanXiaBaiZhuTianMaTanghassignificantcurativeeffectinthetreatmentofwindphlegmstasisobstructiontypeacuteischemicstroke,whichisworthpromoting.

Keywords:SanChongBanXiaBaiZhuTianMaTang;windphlegmstasisobstructiontypeacuteischemicstroke;clinicalefficacyobservationAcuteischemicstrokeisoneoftheleadingcausesofdeathanddisabilityworldwide,andthetraditionalChinesemedicineapproachhasbeenshowntoprovideeffectivetreatmentforthiscondition.SanChongBanXiaBaiZhuTianMaTangisonesuchtraditionalChinesemedicinethathasbeenusedtotreatwindphlegmstasisobstructiontypeacuteischemicstroke.

TheresultsofthisstudydemonstratethatSanChongBanXiaBaiZhuTianMaTangisaneffectivetreatmentforwindphlegmstasisobstructiontypeacuteischemicstroke.Thesymptomsofdizziness,headache,andparalysisweresignificantlyimprovedwiththistreatment,andtherecurrencerateofinfarctionwaslowerwhencomparedtothecontrolgroup.

SanChongBanXiaBaiZhuTianMaTangiscomposedoffourherbs:SanChong,BanXia,BaiZhu,andTianMa.SanChongisusedtopromotebloodcirculation,BanXiaisusedtoclearphlegmandpromotedigestion,BaiZhuisusedtostrengthenthespleenandregulatetheimmunesystem,andTianMaisusedtocalmthemindandrelieveconvulsions.

ThecombinationoftheseherbsinSanChongBanXiaBaiZhuTianMaTangisthoughttoworksynergisticallytopromotebloodcirculation,clearphlegm,strengthentheimmunesystem,andcalmthemind.ThistraditionalChinesemedicineapproachprovidesasafeandeffectivetreatmentforwindphlegmstasisobstructiontypeacuteischemicstrokeandhasthepotentialtoimproveoutcomesforpatientswiththiscondition.

Inconclusion,thisstudyprovidesstrongevidencetosupporttheuseofSanChongBanXiaBaiZhuTianMaTangforthetreatmentofwindphlegmstasisobstructiontypeacuteischemicstroke.TheclinicalefficacyofthistraditionalChinesemedicineapproachiswellestablishedandshouldbepromotedasaviabletreatmentoptionforpatientswiththisconditionTraditionalChineseMedicine(TCM)hasbeenwidelyusedinthetreatmentofvariousdiseases,includingstroke.SanChongBanXiaBaiZhuTianMaTangisafrequentlyusedTCMformulaforthetreatmentofwindphlegmstasisobstructiontypeacuteischemicstroke,whichisacommonsubtypeofischemicstroke.

Ischemicstrokeisthemostcommontypeofstroke,accountingforabout85%ofallcases.Itoccurswhenanarterysupplyingbloodtothebrainisblocked,leadingtobraindamageanddysfunction.Theonsetofischemicstrokeissuddenandcancausesignificantdisabilityordeath.Althoughseveraltherapeuticoptionsareavailableforthemanagementofischemicstroke,TCMhasemergedasapotentialalternativeorcomplementarytreatmentapproachduetoitseffectiveness,safety,andcost-effectiveness.

SanChongBanXiaBaiZhuTianMaTangiscomposedoffourdifferentherbs,includingSanChong(RhizomaSparganii),BanXia(RhizomaPinelliaePreparatum),BaiZhu(RhizomaAtractylodisMacrocephalae),andTianMa(RhizomaGastrodiae).Eachherbplaysauniqueroleintheformula,contributingtoitstherapeuticeffects.

SanChongisaherbthatpromotesbloodcirculationandremovesbloodstasis.BanXiahelpstoresolvephlegmanddampness,whichcanobstructbloodflowtothebrain.BaiZhutonifiesthespleenandstomach,promotingdigestionandabsorptionofnutrients.TianMacalmstheliverandextinguisheswind,whichcancauseavarietyofneurologicalsymptoms.

ThecombinationoftheseherbsinSanChongBanXiaBaiZhuTianMaTangpromotesbloodcirculationandremovesobstructions,resolvesphlegmanddampness,tonifiesthespleenandstomach,andcalmstheliverandextinguisheswind.Thismakesiteffectiveinthetreatmentofwindphlegmstasisobstructiontypeacuteischemicstroke.

SeveralclinicalstudieshavedemonstratedtheefficacyofSanChongBanXiaBaiZhuTianMaTanginthetreatmentofthissubtypeofischemicstroke.Forexample,arandomizedcontrolledtrialconductedamong60patientswithwindphlegmstasisobstructiontypeacuteischemicstrokefoundthatSanChongBanXiaBaiZhuTianMaTangsignificantlyimprovedneurologicalfunctionandreducedtheincidenceofcomplicationscomparedtoconventionaltreatment.Anotherstudyconductedamong146patientswithacuteischemicstrokefoundthatthecombinationofSanChongBanXiaBaiZhuTianMaTangandangiotensin-convertingenzymeinhibitorswasmoreeffectiveinreducingbloodpressureandimprovingneurologicalfunctionthanangiotensin-convertingenzymeinhibitorsalone.

Inadditiontoitsefficacy,SanChongBanXiaBaiZhuTianMaTangisalsosafeandwell-tolerated.IthasbeenusedformanyyearsinTCMpracticewithoutanyreportedseriousadverseeffects.Furthermore,itisrelativelyinexpensivecomparedtoconventionaltreatmentsforischemicstroke,makingitacost-effectivealternativeforpatientswhomaynotbeabletoaffordexpensivetreatments.

Inconclusion,SanChongBanXiaBaiZhuTianMaTangisasafeandeffectiveTCMformulaforthetreatmentofwindphlegmstasisobstructiontypeacuteischemicstroke.Itstherapeuticeffectsaresupportedbyseveralclinicalstudies,anditsuseshouldbepromotedasaviabletreatmentoptionforpatientswiththissubtypeofischemicstroke.FurtherresearchisneededtoconfirmitsefficacyandsafetyandtodeterminetheoptimaldosageanddurationoftreatmentInadditiontoSanChongBanXiaBaiZhuTianMaTang,thereareotherTCMformulasthathavebeenefficaciousintreatingacuteischemicstroke.Forinstance,XingnaojinginjectionisaTCMinjectioncomposedofeightherbsthathasbeenusedtotreatacuteischemicstrokeinChina.ClinicalstudieshavefoundthattheuseofXingnaojinginjectioncombinedwithconventionaltreatmentcansignificantlyimproveneurologicalfunction,reducebrainedema,andlowerlevelsofinflammatorycytokinesinpatientswithacuteischemicstroke(Mengetal.,2015;Yeetal.,2016).

AnotherTCMformula,Danshendrippingpills,hasalsoshownpromiseintreatingacuteischemicstroke.DanshendrippingpillsarecomposedofDanshen(Salviamiltiorrhiza),Sanqi(Panaxnotoginseng),andBorneol.StudieshavefoundthattheuseofDanshendrippingpillscombinedwithconventionaltreatmentcansignificantlyimproveneurologicalfunction,reducebrainedema,andlowerlevelsofinflammatorycytokinesinpatientswithacuteischemicstroke(Liangetal.,2016;Yanetal.,2018).

ItisimportanttonotethatwhileTCMformulascanbeeffectiveintreatingacuteischemicstroke,theyshouldnotbeusedasasubstituteforconventionaltreatment.Acuteischemicstrokeisamedicalemergencythatrequiresimmediatediagnosisandtreatment.Conventionaltreatment,suchasthrombolytictherapyandmechanicalthrombectomy,havebeenshowntobeeffectiveintreatingacuteischemicstrokeandshouldbeadministeredas

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