Nortadalafil-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemENortadalafil(Standard)Cat.No.:HY-90009RCASNo.:171596-36-4分?式:C??H??N?O?分?量:375.38作?靶點(diǎn):Phosphodiesterase(PDE)作?通路:MetabolicEnzyme/Protease儲(chǔ)存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Nortadalafil(Standard)Nortadalafil的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Nortadalafil?種PDE5抑制劑，?種能夠在保健?品中檢測(cè)到的新型Tadalafil(HY-90009A)類(lèi)似物。Nortadalafil?于勃起功能障礙(ED)研究。Nortadalafil可以通過(guò)閉合雙酮哌嗪環(huán)?產(chǎn)合成。Nortadalafil有望?于肺動(dòng)脈?壓的研究[1][2][3][4][5][6][7]。REFERENCES[1].Daugan,etal.Thediscoveryoftadalafil:anovelandhighlyselectivePDE5inhibitor.2:2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dioneanalogue.JournalofMedicinalChemistry(2003),46(21),4533-4542.[2].PorstH,etal.ChronicPDE-5inhibitioninpatientswitherectiledysfunction-atreatmentapproachusingtadalafilonce-daily.ExpertOpinPharmacother.2012Jul;13(10):1481-94.[3].FreyMK,LangI.Tadalafilforthetreatmentofpulmonaryarterialhypertension.ExpertOpinPharmacother.2012Apr;13(5):747-55.[4].HUANGZHi,etal.DiscoveryofNortadalafilinHealthFoods[J].ChinesePharmaceuticalJournal,2015,50(4):371-374.[5].FukiwakeT,etal.[TheConfigurationofTadalafilandTadalafilAnaloguesFoundinDietarySupplements][J].ShokuhinEiseigakuZasshi.2021;62(2):65-72.[6].BeghynT,etal.PDE5inhibitors:Anoriginalaccesstonovelpotentarylatedanaloguesoftadalafil.BioorgMedChemLett[J].2007Feb1;17(3):789-92.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-5895