Medical Biochemistry知到智慧樹章節(jié)測(cè)試課后答案2024年秋溫州醫(yī)科大學(xué)

MedicalBiochemistry知到智慧樹章節(jié)測(cè)試課后答案2024年秋溫州醫(yī)科大學(xué)第一章單元測(cè)試

Whichsetofaminoacidscanabsorb280nmUVlight?（）

A:Thr&HisB:Met&CysC:Trp&TyrD:Cys&HisE:Glu&Asp

答案:Trp&TyrWhichofthefollowingaminoacidsisinvolvedintheformationofdisulfidebridge?（）

A:tyrosineB:hydroxyprolineC:CysteineD:methionineE:tryptophan

答案:CysteineTheformationofproteinsecondarystructureismainlydependenton（）

A:hydrogenbondB:peptidebondC:disulfidebondD:hydrophobicpackingE:base-stackinginteraction

答案:hydrogenbondEssentialofproteindenaturationis（）

A:breakofpeptidebondsB:ruptureofdisulfidebondC:ruptureofhydrogenbondsD:damageofprimarystructureE:breakofnon-covalentbonds

答案:breakofnon-covalentbondsTheaminoacidwhichdoesnotexistinnaturalproteinsis（）

A:methionineB:lysineC:glycineD:cysteineE:citrulline

答案:citrulline

第二章單元測(cè)試

ThebaseisfoundinmRNAbutnotinDNAis（）

A:TB:GC:UD:AE:C

答案:UIfthecontentofadenineis15%inaDNAdoublehelix,thatofcytosineis（）

A:35%B:15%C:55%D:85%E:75%

答案:35%Whichofthefollowingstatementsaboutnucleosomestructureiscorrect?（）

A:NucleosomespermitefficientpackingofDNAtoaboutoneseventhitsnormalvolume.B:ThemajorhistonescomprisingnucleosomesareH1andH4.C:Alloftheabove.D:ThehistoneassociatedwiththeDNAinthelinkerregionholdingnucleosomesiscalledH2A.E:NucleosomesaresphericalstructurescomprisedofRNA,nonhistoneproteinsandhistoneproteins.

答案:NucleosomespermitefficientpackingofDNAtoaboutoneseventhitsnormalvolume.ThecodoninmRNAreverselycomplementarypairingwithanti-codonUGCintRNAis（）

A:TCGB:GCAC:AUGD:GCTE:ACG

答案:GCAThe5′endofmRNAinmosteukaryoteshas（）

A:-CCAsequenceB:polyAtailC:initiationcodonD:CapstructureE:SDsequence

答案:Capstructure

第三章單元測(cè)試

Thespecificityofenzymeisdeterminedby（）

A:prostheticgroupB:SubstrateC:metalionD:apoproteinE:coenzyme

答案:apoproteinTheeffectofnon-competitiveinhibitoronenzyme-catalyzedvelocityis（）

A:Kmdecreased,VmaxdecreasedB:Kmincreased,VmaxunchangedC:Kmdecreased,VmaxunchangedD:Kmunchanged,VmaxdecreasedE:Kmdecreased,Vmaxincreased

答案:Kmunchanged,VmaxdecreasedAnalogofsulfonamideis（）

A:glutamateB:tetrahydrofolicacid(THFA)C:dihydrofolicacid(DHFA)D:paraaminobenzoicacid(PABA)E:folicacid(FA)

答案:paraaminobenzoicacid(PABA)Thephysiologicalsignificanceofzymogenactivationis（）

A:toresumeenzymeactivityB:toprotectenzymeactivityC:tofacilitategrowthD:toacceleratemetabolismE:toavoidself-damage

答案:toavoidself-damageIftheenzymaticvelocityis90%ofVmax,[S]shouldbe（）timesofKm.

A:8B:5C:90D:4.5E:9

答案:9

第五章單元測(cè)試

Whichcoenzymeinpyruvatedehydrogenasecomplexservesasthefinalhydrogensacceptor?（）

A:FADB:NAD+C:lipoateD:biotinE:TPP

答案:NAD+Whichpathwayofthefollowingisrelatedtonucleicacidssynthesis?（）

A:GlycogenolysisB:CitricacidcycleC:GluconeogenesisD:PentosephosphatepathwayE:Glycolysis

答案:PentosephosphatepathwayThedirectdonorofglucosylgroupinglycogenesisis（）.

A:G-1-PB:UDPGC:GDPGD:CDPGE:G-6-P

答案:UDPGMuscleglycogencannotreplenishbloodsugarbecausemusclecellslack（）

A:pyruvatecarboxylaseB:glucose-6-phosphataseC:Phosphofructokinase-1D:pyruvatekinaseE:hexokinase

答案:pyruvatekinaseWhichofthefollowinghormonescanlowerbloodglucose？（）

A:glucocorticoidB:glucagonC:insulinD:adrenalinE:thyroxine

答案:insulin

第六章單元測(cè)試

Whichofthefollowingenzymescatalyzestheratecontrollingstepinfattyacidbiosynthesis?（）

A:dehydrataseB:enoylACPreductaseC:acetyl-CoAcarboxylaseD:synthetaseE:deacylase

答案:acetyl-CoAcarboxylaseWhichofthefollowingisanintermediateinketonebodysynthesis?（）

A:citrateB:3-hydroxy-3-methylglutaryl-CoAC:cyanocobalamin(VitaminB12)D:phosphopantetheineE:biotin

答案:3-hydroxy-3-methylglutaryl-CoAIndicatethecorrectsequenceofreactionsemployedforbeta-oxidationofacyl-CoAderivativesfromthelistbelow.（）

A:oxidationcoupledtoNAD,thiolysis,oxidationcoupledtoFAD,hydrationB:oxidationcoupledtoNAD,hydration,oxidationcoupledtoNAD,thiolysisC:oxidationcoupledtoFAD,hydration,oxidationcoupledtoFAD,thiolysisD:oxidationcoupledtoFAD,thiolysisoxidationcoupledtoNAD,hydrationE:oxidationcoupledtoFAD,hydration,oxidationcoupledtoNAD,thiolysis

答案:oxidationcoupledtoFAD,hydration,oxidationcoupledtoNAD,thiolysisHMGCoAcanactasaprecursorforallofthefollowingEXCEPT:（）

A:VitaminB:adrenalcorticalhormones.C:lecithin.D:bileacids.E:estrogen.

答案:lecithin.Fattyacidsfromadiposetissuearetransportedtositesofutilizationintheformof（）

A:verylowdensitylipoproteins.B:chylomicrons.C:highdensitylipoproteins.D:freefattyacidsboundtoserumalbumin.E:triglyceridesboundtoserumalbumin.

答案:freefattyacidsboundtoserumalbumin.

第七章單元測(cè)試

Whichofthefollowingcomponentsofthemitochondrialelectrontransportsystemareincapableofcarrying2electrons?（）

A:FADB:cytochromeCC:FMND:NAD+E:Ubiquinone

答案:cytochromeCThemainfunctionoftheglycerolphosphateshuttleisin（）

A:thetransportofreducingequivalentsintomitochondriafromNADHformedduringglycolysis.B:theβ-oxidationoffattyacids.C:anaerobicglycolysisforregenerationofNAD.D:thebiosynthesisoftriacylglycerols.E:thebiosynthesisofserineforuseinmitochondrialproteinsynthesis.

答案:thetransportofreducingequivalentsintomitochondriafromNADHformedduringglycolysis.Theuncouplingofoxidativephosphorylationfoundinthebrownfatmitochondriaofanewborninfantmightbeofphysiologicalimportancebecause（）

A:itincreasesCO2intheblood.B:itproducedheat.C:itraisestheoxygenlevelintheblood.D:itproduceswater.E:itallowsATPformation

答案:itproducedheat.ATPsynthasecarryoutsubstratelevelphosphorylations.（）

A:對(duì)B:錯(cuò)

答案:錯(cuò)ThemitochondrialelectrontransportsystemresponsibleforreoxidationofNADHandelectrontransfertooxygenislocatedininnermembraneofthemitochondria.（）

A:錯(cuò)B:對(duì)

答案:對(duì)

第八章單元測(cè)試

AllofthefollowingareessentialaminoacidsEXCEPT（）

A:TryptophanB:threonineC:valineD:serineE:lysine

答案:serineTheaminoacidthatisinvolvedinalmosteveryaminotransferasereactionis（）

A:pyruvateB:aspartateC:GlutamineD:lysineE:glutamate

答案:glutamateThenitrogensinureaoriginateMOSTDIRECTLY(fewestnumberofsteps)from（）

A:NH3andglutamineB:NH3andglutamateC:freeammoniaD:carbamoylphosphateandaspartateE:alanineandglutamate

答案:carbamoylphosphateandaspartatePyridoxalphosphateactsascoenzymeinmost（）

A:transaminationreactions.B:kinasereactions.C:noneoftheaboveD:carbondioxideincorporatedreactions.E:dehydrogenationreactions.

答案:transaminationreactions.Theprimaryfunctionoftheureacycleis（）

A:theturnoverofexcessarginineB:theproductionofthecitricacidcycleintermediatefumarateC:thesynthesisofaspartateD:toconverttoxicammoniatoureawhichcanbeexcretedE:thesynthesisofornithineforspermidinesynthesis

答案:toconverttoxicammoniatoureawhichcanbeexcreted

第九章單元測(cè)試

Whichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?（）。

A:GlutamineB:FumarateC:FormicacidD:Glycine

答案:GlutamineWhichofthefollowingsubstancedirectlylinksnucleotidesynthesisandglucosemetabolism?（）。

A:Ribose-5-phosphateB:GlucoseC:Glucose-6-phosphateD:Glucose-6-phosphate

答案:Ribose-5-phosphateWhichofthefollowingisnotaphysiologicalroleofnucleotide?（）。

A:componentsofthecoenzymesFADandCoAB:intermediatesforbiosyntheticprocessesC:carriersofchemicalenergyD:componentsofmanyproteins

答案:componentsofmanyproteinsTheprincipalnitrogenousurinaryexcretionproductinhumansresultingfromthecatabolismofAMPis（）

A:thiamineB:creatinineC:uricacidD:urea

答案:uricacidWhichoneofthefollowingdoesnotoccursinthedegradationpathwayofAMP?（）

A:AdenineisconvertedtohypoxanthineB:AdenosineisconvertedtoadenineC:AMPisconvertedtoadenosineD:TheendproductisCO

答案:TheendproductisCO

第十章單元測(cè)試

Allproductsofliverbiotransformationarenontoxic.（）

A:對(duì)B:錯(cuò)

答案:錯(cuò)Intheenterohepaticcirculationonlyalittlefractionofbileacidsarereabsorbedintheintestine.（）

A:對(duì)B:錯(cuò)

答案:錯(cuò)Whichofthefollowingreactionsisthemostcommonconjugationintheliver?（）

A:ConjugationwithacetateB:ConjugationwithglucuronicacidC:ConjugationwithsulfateD:Conjugationwithglutathione

答案:ConjugationwithglucuronicacidWhichofthefollowingreactionsisthemostcommonconjugationintheliver?（）

A:UDPGB:UDPGAC:PAPSD:SAM

答案:PAPSWhichofthefollowingenzymeistherate-limitingenzymeintheprocessofbileacidssynthesis?（）

A:7α-hydroxylationB:7α-dehydroxylationC:3α-dehydroxylationD:3α-hydroxylation

答案:7α-hydroxylation

第十一章單元測(cè)試

Thebilirubinissparinglysolubleinplasmaandwater.（）

A:錯(cuò)B:對(duì)

答案:對(duì)Unconjugatedbilirubincanbesecretedintotheurineinourbodies.（）

A:對(duì)B:錯(cuò)

答案:錯(cuò)Whatdothedailybilirubinformationderivemainlyfrom?（）

A:cytochromeB:hemoglobinC:myoglobinD:bilin

答案:hemoglobinWhat‘sthematerialsofhemesynthesis?（）

A:glycine,succinylCoA,Fe2+B:glycine,acetyl-CoA,Fe2+C:arginine,succinylCoA,Fe2+D:glycine,acetyl-CoA,Cu2+

答案:glycine,succinylCoA,Fe2+Howmanyoxygenscanamoleculeofhemoglobinbind?（）

A:1B:2C:4D:3

答案:4

第十二章單元測(cè)試

ThesequenceofoneDNAstrandisATGCAA,thecomplementarystrandofDNAis（）

A:TTGCATB:TACGTTC:UUGCAUD:UAGCAAE:ATGCAA

答案:TTGCATTheenzymeinchargeofproofreadingfunctioninDNAreplicationis（）

A:TopoisomeraseB:DNApolymeraseC:HelicaseD:PrimaseE:DNAligase

答案:DNApolymeraseInthereplicationofeukaryoticDNA,（）

A:theleadingstrandissynthesizedinthedirectiontakenbythereplicationfork.B:bothleadingstrandandlaggingstrandaresynthesizedinadirectionoppositetothatinwhichthereplicationforkmoves.C:thelaggingstrandissynthesizedinthedirectiontakenbythereplicationfork.D:thetemplateisreadinthe5’3’direction.E:anewDNAstrandisalwayssynthesizedinthe3’5’direction.

答案:theleadingstrandissynthesizedinthedirectiontakenbythereplicationfork.Whatisthefunctionofthe3'to5'exonucleaseactivityofbacterialDNApolymerases?（）

A:removesmismatchedbasesduringreplicationB:initiatesmRNAsynthesisC:removestheRNAprimersofOkazakifragmentsD:processesprecursorsofribosomalRNA

答案:removesmismatchedbasesduringreplicationAllofthefollowingstatementsconcerningDNAreplicationinprokaryotesaretrueEXCEPT____?（）

A:Replicationisbidirectionalfromasingleinitiationpoint.B:Replicationoccursina5'to3'direction.C:OkazakifragmentsarejoinedbyDNApolymeraseIII.D:UnwindingofthedoublehelixrequiresATPhydrolysis.

答案:OkazakifragmentsarejoinedbyDNApolymeraseIII.DNApolymeraseIIIcanonlyaddnucleotidestoanexistingchain,so_____isrequired.（）

A:helicaseB:aDNAprimerC:anRNAprimerD:DNApolymeraseI

答案:anRNAprimerXerodermapigmentosum(xp)resultsfromadeficiencyin_____.（）

A:DNArepairB:collagensynthesisC:atumorsuppressorD:DNAreplication

答案:DNArepairRegardingtheprocessofDNAreplicationinE.coliwhichofthefollowingstatementsisWRONG?（）

A:DNAreplicationisasemiconservativeprocess.B:ThemechanismofreplicationissuchthatthereisaleadingstrandandalaggingstrandateachreplicatingforkC:Thereisauniquesiteatwhichreplicationisinitiated.D:DNAreplicationisunidirectional.

答案:DNAreplicationisunidirectional.DNApolymeraseIdonothas_____.（）

A:3’→5’exonucleaseactivity.B:5’→3’exonucleaseactivity.C:HelicaseactivityD:polymeraseactivity.

答案:HelicaseactivityOkazakifragmentsare_____.（）

A:assembledascontinuousreplication.B:foundontheleadingstrand.C:synthesizedinthe3'to5'direction.D:foundonthelaggingstrand.

答案:foundonthelaggingstrand.

第十三章單元測(cè)試

ThetemplatestrandofDNAis5’-ATTCAG-3’,itstranscriptis（）

A:5’-UAAGUC-3’B:5’-TAAGTC-3’C:5’-CTGAAT-3’D:5’-CUGAAU-3’E:5’-GACTTA-3’

答案:5’-CUGAAU-3’WhichofthefollowingisNOTtrueoftheprokaryotic(E.coli)transcriptionalprocess?（）

A:specificsequencesinthepromoterarenecessaryforstablebindingofRNApolymerase.B:terminationrequiresspecialsequences(signals)inthenascentRNAchain.C:sigmafactorisrequiredonlyduringtheinitiationprocess.D:AseparatehelicaseenzymeisnecessaryforunwindingtheDNAtemplatetocreateanopencomplex.

答案:AseparatehelicaseenzymeisnecessaryforunwindingtheDNAtemplatetocreateanopencomplex.TheTATAboxineukaryotesisa_____.（）

A:5'cap.B:-10sequence.C:corepromoter.D:-35sequence.

答案:corepromoter.Whichofthefollowingstatementsiscorrectaboutprokaryoticgeneexpression?（）

A:Allofthesestatementsarecorrect.B:ProkaryoticmRNAsmusthaveintronssplicedout.C:ProkaryoticmRNAsareoftentranslatedbeforetranscriptioniscomplete.D:ProkaryoticmRNAscontainthetranscriptofonlyonegene.

答案:ProkaryoticmRNAsareoftentranslatedbeforetranscriptioniscomplete.IndicatewhichofthefollowingeventscanoccurduringtheprocessingofeukaryoticmRNAtranscripts.（）

A:Splicingtogetherofexons.B:MethylationofallGresidues.C:Attachmentofapoly(A)tailtothe5’endofthetranscript.D:Excisionsofintrons.

答案:Excisionsofintrons.TheAAUAAAsequenceonaRNAmoleculemarks_____.（）

A:Thesitenearwhichtheprimarytranscriptiscleavedandapoly(A)sequenceisadded.B:Thesitewherethereleasefactorwillbindtoendpolypeptidesynthesis.C:Thesitewhereribosomesbindtoinitiatepolypeptidesynthesis.D:Thesitewheretranscriptionstops.

答案:Thesitenearwhichtheprimarytranscriptiscleavedandapoly(A)sequenceisadded.RNApolymeraseisboundinitiallyto_____ofanoperon?（）

A:structuralgenesB:PromoterC:enhancerD:Operator

答案:PromoterPost-translationalmodificationsofpolypeptidesincludeallthefollowingEXCEPT_____?（）

A:proteasecleavageB:cappingby7-methylguanidineC:removalofmethionineD:disulfidebondformation

答案:cappingby7-methylguanidine

第十四章單元測(cè)試

Thedirectionofproteinsynthesis(polypeptidechain)is（）

A:From3’to5’B:FromNtoCC:NoneofaboveD:FromCtoNE:From5’to3’

答案:FromNtoCThesequenceofnucleotideofinitiationcodenis（）

A:AGUB:UAGC:UGAD:UAAE:AUG

答案:AUGIfthecodenofmRNAisACG,thentheanticodenoftRNAis（）

A:TGCB:GCAC:CGUD:TGCE:UGC

答案:CGUThegeneexp