Ruscogenin-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemERuscogenin(Standard)Cat.No.:HY-N0496RCASNo.:472-11-7分子式:C??H??O?分子量:430.62作用靶點(diǎn):NOD-likeReceptor(NLR);NOD-likeReceptor(NLR)作用通路:Immunology/Inflammation儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Ruscogenin(Standard)是Ruscogenin的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Ruscogenin是從Ophiopogonjaponicus提取的一種重要甾體皂苷元，通過(guò)抑制TXNIP/NLRP3炎癥體激活和MAPK途徑減輕腦缺血誘導(dǎo)的血腦屏障功能障礙，Ruscogenin具有顯著的抗炎和抗血栓活性。Ruscogenin有口服活性[1][2]。REFERENCESCaoG,etal.RuscogeninAttenuatesCerebralIschemia-InducedBlood-BrainBarrierDysfunctionbySuppressingTXNIP/NLRP3InflammasomeActivationandtheMAPKPathway.IntJMolSci.2016Aug29;17(9).pii:E1418.HuangYL,etal.Possiblemechanismoftheanti-inflammatoryactivityofruscogenin:roleofintercellularadhesionmolecule-1andnuclearfactor-kappaB.JPharmacolSci.2008Oct;108(2):198-205.CaoG,etal.RuscogeninAttenuatesCerebralIschemia-InducedBlood-BrainBarrierDysfunctionbySuppressingTXNIP/NLRP3InflammasomeActivationandtheMAPKPathway.IntJMolSci.2016Aug29;17(9).pii:E1418.HuangYL,etal.Possiblemechanismoftheanti-inflammatoryactivityofruscogenin:roleofintercellularadhesionmolecule-1andnuclearfactor-kappaB.JPharmacolSci.2008Oct;108(2):198-205.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax: