Gene Therapy 基因治療.ppt

1、Gene Therapy,GAC1 Clarence,Introduction,What is a gene?,basic unit of heredity in a living organism,What is gene therapy,hereditary diseases insertion of genes - individuals cells & tissues a defective mutant allele is replaced with a functional one,How it works,“normal” gene - patients “abnormal” o

2、ne target cells by a vector retroviruses adenoviruses adeno-associated viruses herpes simplex viruses,Development,2003, UCLA, potential treatment for Parkinsons disease 2006,National Institutes of Health, killer T-cell helped treat cancer 2007, Moorfields Eye Hospital and University College Londons

3、Institute of Ophthalmology, first gene therapy trial for inherited retinal disease.,Debate,Pros,Advanced technology is supposed to benefit mankind Stretch mankinds lives Glimmer of hope Rid inherited diseases that normally treatment cannot be avoided,Cons,Ethical Religious Medical,Religious,Religiou

4、s,Medical,Conclusion,Human Genome Project in 2003 Other advance of science The gene therapy will succeed,Reference,Gene Therapy (2008), ornl online Available at: /sci/techresources/Human_Genome/medicine/genetherapy.shtml Accessed 4 November 2008 Gene therapy (2008), Wikipedia onlin

5、e Available at: /wiki/Gene_therapy Accessed 4 November 2008 Gene Therapy for Cancer Q & A (2008), National Cancer Institute online Available at: /cancertopics/factsheet/Therapy/gene Accessed 3 November 2008 Human genome project (2008), Wikipedia online Avail

6、able at: /wiki/Human_genome_project Accessed 4 November 2008 The Ethics of Gene Therapy (2008) ,ndsu online Available at:/instruct/mcclean/plsc431/students/bergeson.htm Accessed 4 November 2008 Weighing the pros and cons of gene therapy (2008),helium onl

7、ine.Available at: Accessed 4 November 2008 What are the ethical issues surrounding gene therapy (2008), Genetics Home Reference online. Available at: /handbook/therapy/ethics Accessed 3 November 2008,Reference,DNA (2008), battlingforhealth on line. Available at: accessed 1 Decem

8、ber 2008 GeneDoping (2008), scienceblogs on line. Available at: accessed 1 December 2008 Gene therapy (2008), blogger on line. Available at: accessed 1 December 2008 iStock_cancer (2008), biosulf on line . Available at: /1/images/iStock_cancer1120164XSmall.jpg accessed 25 Decemb

9、er 2008 cancer patient (2008), cancer%20patient on line . Available at: accessed 25 December 2008,Reference,large_therapy (2008), mlive on line . Available at: accessed 25 December 2008 cancer patient (2008), bbc on ling . Available at: http:/newsimg.bbc.co.uk/media/images/44851000/jpg/_44851983_cancer_patient_512.jpg accessed 25 December 2008 gene (1008), oncolink on line . Available at: accessed 25 December 2008 gene (2008), photobucket on line . Available at: accessed 25 December 2008 creation (2008), aerenlund on line . Available at: http:/www.aerenlund