健脾利濕益腎法治療慢性腎炎蛋白尿的臨床效果觀察

1、健脾利濕益腎法治療慢性腎炎蛋白尿的臨床效果觀察摘要目的 探討健脾利濕益腎法治療慢性腎炎蛋白尿的臨床效 果。方法 將162例慢性腎炎蛋白尿患者分為觀察組和對(duì)照組，各81例, 觀察組給予健脾利濕益腎類自制中藥治療，對(duì)照組給予腎炎舒片口服治 療，觀察兩組患者的治療效果。結(jié)果 觀察組患者治療總有效率為96. 30%, 明顯高于對(duì)照組的81.48% (p<0.05)；觀察組治療后24 h尿蛋白定量、清 蛋白、血尿素氮及血肌酹指標(biāo)結(jié)果均低于對(duì)照組(p005)。結(jié)論 健脾 利濕益腎法治療慢性腎炎蛋白尿可提高治療效果，對(duì)腎臟功能有一定的保 護(hù)作用，值得臨床推廣應(yīng)用。關(guān)鍵詞慢性腎炎；蛋白尿；健脾；利濕；益

2、腎中圖分類號(hào)r692. 3 文獻(xiàn)標(biāo)識(shí)碼a 文章編號(hào)1674-4721 (2013) 11 (c) -0118-02clinical observation of spleen nourishing-kidney strengthening-dampness eliminaling in the treatment of chronic nephritis proteinuriahe dong-xiangdepartment of tradition且1 chinese medicine, sanli substation of schistosomiasis prevention and co

3、ntrol station of jinxian county in jiangxi province, jinxian 331709, chinaabstract objective to discuss the clinical effect of spleennourishing-kidney strengthening-dampness eliminating in the treatment of chronic nephritis proteinuria. methods 162 patients with chronic nephritis proteinuria were as

4、signed to observation group and control group, with 81 patients in each group. observation group was treated with homemade spleen nourishing-kidney strengthening-dampness eliminating traditional chinese medicine and control group was treated with shenyonshu oral tablets. the therapeutic effects wore

5、 observed in the two groups. results the total effective rate of observation group was 96. 30%, significantly higher than that of control group (81. 48%) (p<0. 05) 24 hours urinary protein, albumin, blood urea nitrogen and serum creatinine of observation group after treatment were lower than that

6、 of control group ( p0.05 ).conclusion the spleen nourishing-kidneystrengthening-dampness eliminating therapy is conducive to improving therapeutic effects on chronic nephritis proteinuria and providing protective effects on renal functions, thus it is worthy of clinical application.key words chroni

7、c nephritis； proteinuria； spleen nourishing； dampness eliminating； kidney strengthening慢性腎小球腎炎是臨床常見的一種慢性腎病，以中青年男性發(fā)病居 多，臨床表現(xiàn)主要以蛋口尿、血尿、水腫、高血壓等為主，多數(shù)患者起病 較為隱匿、進(jìn)展較為緩慢。臨床將尿檢出現(xiàn)蛋白尿、血尿、管型尿的患者, 均考慮為慢性腎小球腎炎。對(duì)于慢性腎炎的治療，目前尚無(wú)特效治療方案, 臨床多以對(duì)癥支持治療為主1。本文采用健脾利濕益腎法治療慢性腎炎 蛋白尿，現(xiàn)將治療效果報(bào)道如下。1資料與方法1.1 一般資料選取2008年1月2013年1月本院治療的慢性腎炎蛋口尿患者162 例，采取隨機(jī)數(shù)字表法將英分為觀察組和対照組，各81例。觀察組：男 52例，女29例；年齡1946歲，平均(38.25±4. 14)歲；病程12個(gè)月 10年，平均(3.15±1.05)年。對(duì)照組：男53例，女28例；年齡20 47歲，平均(3846±436)歲；病程12個(gè)月10年，平均(3. 26±1. 13) 年。兩組患者的性別、年齡、病程等一般資料比較差異無(wú)統(tǒng)計(jì)學(xué)意義 (p>0. 05),具有可比性。1. 2診斷標(biāo)準(zhǔn)全部納入對(duì)象均符合中華中醫(yī)藥學(xué)會(huì)腎病分會(huì)關(guān)于慢性腎小球腎炎