常用有機(jī)堿排序(共17頁(yè))

1、Dissociation Constants Of Organic Acids And BasesThis table lists the acid-base dissociation constants of over 600 organic compounds, including many amino acids. All data apply todilute aqueous solutions and are presented in the form of pKa, which is the negative of the logarithm of the acid dissoci

2、ation constant Ka.MolecularformulaNameStepTI°CpKaCH2O2Formic acid203.75CH4N2OUrea210.10CH5NMethylamine2510.63C2HCl3O2Trichloroacetic acid250.70C2H2Cl2O2Dichloroacetic acid251.48C2H2O3Glyoxylic253.18C2H2O4Oxalic acid1251.232254.19C2H3BrO2Bromoacetic acid252.69C2H3ClO2Chloroacetic acid252.85C2H3I

3、O2Iodoacetic acid253.12C2H4OSThioacetic acid253.33C2H4O2Acetic acid254.76C2H4O3Glycolic acid253.83C2H5NEthyleneimine258.01C2H5NOAcetamide250.63C2H5NO2Glycine1252.352259.78C2H6O2Ethylene glycol2514.22C2H7AsO2Cacodylic acid1251.572256.27C2H7NDimethylamine2510.68C2H7NEthylamine2510.70C2H7NOEthanolamine

4、259.50C2H7NO3STaurine1251.52259.061C2H7NSCysteamine1258.3522510.81C2H8N21,2-Ethanediamine1010.712207.564C3H3NO2Cyanoacetic acid252.45C3H3NSThiazole202.44C3H4N21H-Imidazole256.953C3H4N2S2-Thiazolamine205.36C3H4O2Acrylic acid254.25C3H4O3Pyruvic acid252.39C3H4O4Malonic acid1252.832255.69C3H5ClO22-Chlor

5、opropanoic acid252.83C3H5ClO23-Chloropropanoic acid253.98C3H6N6Melamine255.00C3H6O2Propanoic acid254.86C3H6O33-Hydroxypropanoic acid254.51C3H6O3Lactic acid1003.08C3H6O4Glyceric acid253.52C3H7NAzetidine2511.29C3H7NO2L-Alanine1252.342259.87C3H7NO2b-Alanine1253.5522510.24C3H7NO2Methylglycine1252.212251

6、0.12C3H7NO2SCysteine1251.922258.3732510.70C3H7NO3Serine1252.192259.21C3H7NO5Sl-Cysteic acid1251.32251.93258.70C3H7N3O2Glycocyamine252.82C3H8O3Glycerol2514.15C3H9NPropylamine2010.60C3H9NTrimethylamine259.80C3H9NO1-Amino-2-methoxyethane109.89C3H9NOTrimethylamine oxide254.65C3H10N21,2-Propanediamine125

7、9.822256.61C3H10N21,3-Propanediamine11010.942109.03C3H11N31,2,3-Triaminopropane1209.592207.95C4H4N2Pyrazine270.65C4H4N2Pyridazine202.24C4H4N2O3Barbituric acid254.01C4H4N2O5Alloxanic acid256.64C4H4N4O25-Nitropyrimidinamine200.35C4H4O4trans-Fumaric acid1183.032184.44C4H4O4Maleic acid1251.832256.07C4H4

8、O5Oxaloacetic acid1252.222253.8932513.03C4H5N32-Pyrimidinamine203.45C4H6N21-Methylimidazol256.95C4H6N4O3Allantoin258.96C4H6O23-Butenoic acid254.34C4H6O2trans-Crotonic acid254.69C4H6O3Acetoacetic acid183.58C4H6O32-Oxobutanoic acid252.50C4H6O4Methymalonic acid1253.072255.76C4H6O4Succinic acid1254.1622

9、55.61C4H6O5Malic acid1253.402255.11C4H6O6a-Tartaric acid1252.982254.34C4H6O6meso-Tartaric acid1253.222254.82C4H6O8Dihydroxytartaric acid251.92C4H7CIO22-Chlorobutanoic acidRT2.86C4H7CIO23-Chlorobutanoic acidRT4.05C4H7CIO24-Chlorobutanoic acidRT4.52C4H7NO24-Cyanobutanoic acid252.42C4H7NO3N-Acetylglyci

10、ne253.669C4H7NO4Aspartic acid1251.992253.903259.90C4H7N3OCreatinine1254.8329.2C4H8N2O3Asparagine1202.172208.80C4H8N2O3N-Glycylglycine253.139C4H8O2Butanoic acid254.83C4H8O22-Methylpropanoic acid254.88C4H8O33-Hydroxybutanoic acid254.70C4H8O34-Hydroxybutanoic acid254.72C4H9NPyrrolidine2511.27C4H9NOMorp

11、holine258.33C4H9NO22-Aminobutanoic acid1252.292259.83C4H9NO24-Aminobutanoic acid1254.03122510.556C4H9NO2N,N-Dimethylglycine259.89C4H9NO22-Methylalanine1252.3622510.21C4H9NO2SHomocysteine1252.222258.8732510.86C4H9NO3Homoserine1252.712259.62C4H9NO3DL-Methoxyalanine252.037C4H9NO3Threonine1252.092259.10

12、C4H9N3O2Creatine1252.6322514.3C4H10N2Piperazine1239.832235.56C4H10N2O22,4-Diaminobutanoic acid1251.852258.2432510.44C4H11NButylamine2010.77C4H11Nsec-Butylamine2510.56C4H11Ntert-Butylamine2510.68C4H11NDiethylamine4011.02C4H12N21,4-Butanediamine12010.802209.35C4H12O21,2-Dimethylaminoethane12510.402258

13、.26C5H4BrN3-Bromopyridine252.84C5H4CIN3-Chloropyridine252.84C5H4N4Purine1202.302208.96C5H4N4O3Uric acid123.89C5H5NPyridine255.25C5H5NO4-Pyridinol1203.2022011.12C5H5NO2(1H)-Pyridinone1200.7522011.65C5H5N51H-Purin-6-amine1254.122259.83C5H6N22-Methylpyrazine271.45C5H6N22-Pyridinamine206.82C5H6N24-Pyrid

14、inamine259.114C5H6O41,1-Cyclopropanedicarboxylic acid1251.822257.43C5H6O4Itaconic acid1253.852255.45C5H6O4Mesaconic acid1253.092254.75C5H6O52-Oxoglutaric acid1252.472254.68C5H7NO3L-2-Pyrrolidone-5-carboxylic acid253.32C5H7N3Methylaminopyrazine253.39C5H7N32,5-Pyridinediamine206.48C5H8N22,4-Dimethylim

15、idazzol258.36C5H8O4Dimethylmalonic acid253.15C5H8O4Glutaric acid1254.312255.41C5H8O4Methylsuccinic acid1254.132255.64C5H9NO2Proline1251.95222510.64C5H9NO35-Aminolevulinic acid1254.052258.90C5H9NO3trans-4-Hydroxyroline1251.8182259.662C5H9NO38-Hydroxypurine1202.562208.26C5H9NO4L-Glutamic acid1252.1322

16、54.31C5H9N3Histamine1256.042259.75C5H10N2O2Diaminopimelic acid1251.82252.23258.84259.9C5H10N2O3L-Glutamine1252.172259.13C5H10N2O3Glycylalanine253.15C5H10N2O4Glycylserine1252.982258.38C5H10O22-Methylbutanoic acid254.80C5H10O23-Methylbutanoic acid254.77C5H10O2Pentanoic acid254.84C5H10O2Trimethylacetic

17、 acid 255.03C5H11NN-Methylpyrrolidine2510.32C5H11NPiperidine2511.123C5H11NO25-Aminopentanoic acid1254.2722510.766C5H11NO2Betaine01.83C5H11NO2Norvaline1252.322259.81C5H11NO2N-Propylglycine1252.3522510.19C5H11NO2Valine1252.292259.74C5H11NO2SMethionine1252.132259.27C5H12N2O2Ornithine1251.7052258.693251

18、0.76C5H13N1-Aminno-2,2-dimethylpropane2510.15C5H13NDiethylmethylamine2510.35C5H13N3-Methyl-1-butanamine2510.60C5H13N2-Methyl 2-butanamine1910.85C5H13N3-Pentanamine1710.59C5H13NPentylamine2510.63C5H14NOCholine2513.9C5H14N2Cadaverine12510.0522510.93C6H3CIN46-Cbloropteridine203.68C6H3N3O7Picric acid250

19、.38C6H4Cl2O2,3-Dichlorophenol257.44C6H4N2O35-Hydroxylysine252.13C6H4N2O52,4-Dinitrophenol153.96C6H4N2O53,6-Dinitrophenol155.15C6H4N4Pteridine204.05C6H5Br2N3,5-Dibromoaniline252.34C6H5CIO2-Chlorophenol258.49C6H5CIO3-Chlorophenol258.85C6H5CIO4-Chlorophenol259.18C6H5CI2N2,4-Dichloroaniline222.05C6H5NO2

20、-Pyridinecarboxaldehyde203.80C6H5NO2Nitrobenzene03.98C6H5NO2Picolinic acid1251.072255.25C6H5NO23-Pyridinecarboxylic acid254.85C6H5NO24-Pyridinecarboxylic acid254.96C6H5NO32-Nitrophenol257.17C6H5NO33-Nitrophenol258.28C6H5NO34-Nitrophenol257.15C6H5N5O2-Amino-4-hydroxypteridine1202.272207.96C6H5N5O2Xan

21、thopterin2206.593209.31C6H6BrN2-Bromoaniline252.53C6H6BrN3-Bromoaniline253.58C6H6BrN4-Bromoaniline253.86C6H6CIN2-Chloroaniline252.65C6H6CIN3-Chloroaniline253.46C6H6CIN4-Chloroaniline254.15C6H6FN2-Fluoroaniline253.20C6H6FN3-Fluoroaniline253.50C6H6FN4-Fluoroaniline254.65C6H6IN2-Iodoaniline252.60C6H6N2

22、O2-Pyridinecarboxaldehyde,oxime1203.5922010.18C6H6N2O22-Nitroaniline25-0.26C6H6N2O23-Nitroaniline252.466C6H6N2O24-Nitroaniline251.0C6H6OPhenol209.89C6H6O2Hydroquinone2010.35C6H6O2Pyrocatechol209.85C6H6O2Resorcinol259.81C6H6O3SBenzenesulfonic acid250.70C6H6O6cis-Aconitic acid251.95C6H6O6trans-Aconiti

23、c acid1252.802254.46C6H7NAniline254.63C6H7N2-Methylpyridine205.97C6H7N3-Methylpyridine205.68C6H7N4-Methylpyridine206.02C6H7NOMethoxypyridine256.47C6H7NO3So-Aminobenzenesulfonic acid252.48C6H7NO3Sm-Aminobenzenesulfonic acid253.73C6H7NO3Sp-Aminobenzenesulfonic acid253.24C6H8N2N-Methylpyridinamine209.6

24、5C6H8O6Ascorbic acid1244.1021611.79C6H8O7Citric acid1203.142204.773206.39C6H8O7Isocitric acid1253.292254.713256.40C6H9NO6g-Carboxyglutamic acid1251.72253.23254.754259.9C6H9N34,6-Dimethylpyrimidinamine204.82C6H9N3O2Histidine1251.802256.043259.33C6H10O32-Oxo-3-methylpentanoic acid252.3C6H10O4Adipic ac

25、id1254.432255.41C6H10O43-Methylglutaric acid254.24C6H11NO2l-Pipecolic acid1252.2822510.72C6H11NO3Adiparnic acid254.63C6H11NO42-Aminoadipic macid1252.142254.213259.77C6H11N3O4Glycylasparagine1252.9422188.44C6H11N3O4N-(N-Glycylglycyl)glycine1253.2252258.09C6H12N2O4S2Cystine1352.12358.0C6H12O2Hexanoic

26、acid254.85C6H12O24-Methylpentanoic acid184.84C6H13NCyclohexylamine2410.66C6H13N1,2-Dimethylpyrrolidine2610.20C6H13N1-Methylpiperidine2510.08C6H13NO26-Aminohexanoic acid1254.37322510.804C6H13NO2Isoleucine1252.322259.76C6H13NO2L-Leucine1252.3282259.744C6H13NO2Norleucine1252.3352259.83C6H13N3O3Citrulli

27、ne1252.432259.69C6H14N2cis-1,2-Cyclohexanediamine1209.932206.13C6H14N2trans-1,2-Cyclohexanediamine1209.942206.47C6H14N22,5-Dimethylpiperazine1259.662255.20C6H14N2O2Lysine1252.162259.0632510.54C6H14N4O2Arginine1251.822258.9932512.48C6H15N3-Amino-3-methylpentane1611.01C6H15NDiisopropylamine2511.05C6H1

28、5NHexylamine2510.56C6H15NTriethylamine2510.75C6H16N2Hexamethylenediamine1011.8572010.762C7H5BrO22-Bromobenzoic acid252.84C7H5BrO23-Bromobenzoic acid253.86C7H5CIO22-Chlorobenzoic acid252.92C7H5CIO23-Chlorobenzoic acid253.82C7H5CIO24-Chlorobenzoic acid253.98C7H5IO22-Iodobenzoic acid252.85C7H5IO23-Iodo

29、benzoic acid253.80C7H5NO3SSaccharin1811.68C7H5NO4Dinicotinic acid252.80C7H5NO4Dipicolinic acid1252.162254.76C7H5NO4Lutidinic acid252.15C7H5NO42-Nitrobenzoic acid182.16C7H5NO43-Nitrobenzoic acid253.47C7H5NO44-Nitrobenzoic acid253.41C7H5NO4Quinolinic acid1252.432254.78C7H6N2Benzimidazole255.532C7H6N4O

30、6-Hydroxy-4-methylpteridine1204.082206.41C7H6O2Benzoic acid254.19C7H6O3o-Hydroxy-4-methylpteridine1192.9721813.40C7H6O3m-Hydroxybenzoic acid1194.062199.92C7H6O3p-Hydroxybenzoic acid1194.482199.32C7H6O42,5-Dihydroxybenzoic acid1252.97C7H6O43,4-Dihydroxybenzoic acid1254.482258.8332512.6C7H6O43,5-Dihydroxybenzoic acid1254.04C7H6O4Dihydroxymalic acid251.92C7H6O5Gallic acid254.41C7H6O52,4,6-Trihydroxybenzoic acid251.68C7H7NO22-Aminobenzoic acid1252.1082254.946C7H7NO23-Aminobenzoic acid2254.78C7H7NO24-Animobenzoic acid1252.5012254.874C7H8N4O2Theobromine187.89C7H8Oo-Cresol2510.20C7H8O