Pamabrom-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPamabromCat. No.: HY-17391CAS No.: 606-04-2分式: CHBrNO分量: 348.2作靶點: Others作通路: Others儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 150 mg/mL (430.79 mM; Need ultrasonic)Mass Solvent1 mg 5

2、mg 10 mg Concentration制備儲備液1 mM 2.8719 mL 14.3596 mL 28.7191 mL5 mM 0.5744 mL 2.8719 mL 5.7438 mL10 mM 0.2872 mL 1.4360 mL 2.8719 mL請根據(jù)產品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內實驗 請根據(jù)您的實驗動物和給藥式選擇適當?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實驗結果的可靠性，體內實驗的作液，建議您現(xiàn)現(xiàn)配，當天使；澄清的儲備液可以根據(jù)儲存條件，適當保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體

3、積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.67 mg/mL (7.67 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.67 mg/mL (7.67 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.67 mg/mL (7.67 mM); Clear solution1/2 Master o

4、f Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 Pamabron利尿劑，可緩解經相關癥狀，其有效成分為8-bromotheophylline。REFERENCES1. Ortiz MI, Rangel-Flores E, Carrillo-Alarcn LC, et al. Prevalence and impact of primary dysmenorrhea among Mexican high schoolstudents. Int J Gynaecol Obstet. 2009 Dec;107(3):240-3.

5、2. Swanson JK, English JC 3rd. Serum sickness-like reaction to Pamabrom. J Drugs Dermatol. 2006 Mar;5(3):284-6.3. Di Girolamo G, Snchez AJ, De Los Santos AR, et al. Is acetaminophen, and its combination with pamabrom, an effective therapeuticoption in primary dysmenorrhoea? Expert Opin Pharmacother. 2004 Mar;5(3):561-70.4. PamabromMcePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 0