Mebendazole - Parasite 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEMebendazoleCat. No.: HY-17595CAS No.: 31431-39-7分式: CHNO分量: 295.29作靶點(diǎn): Parasite作通路: Anti-infection儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 23 mg/mL (77.89 mM)* means soluble, but sat

2、uration unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 3.3865 mL 16.9325 mL 33.8650 mL5 mM 0.6773 mL 3.3865 mL 6.7730 mL10 mM 0.3387 mL 1.6933 mL 3.3865 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Mebendazole效譜驅(qū)藥，同時(shí)也被報(bào)道是hedgehog抑制劑。REFERENCES1. Liu C, et al. In v

3、ivo and in vitro efficacies of mebendazole, mefloquine and nitazoxanide against cyst echinococcosis. Parasitol Res.2015 Mar 15.1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE2. Pawluk SA, et al. A review of pharmacokinetic drug-drug interactions with the anthelmintic medications albendazole and me

4、bendazole.Clin Pharmacokinet. 2015 Apr;54(4):371-83.3. Speich B, et al. Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate,and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: a four-arm, random4. Larsen AR, et al. Repurposing the antihelmintic mebendazole as a hedgehog inhibitor. Mol Cancer Ther. 2015 Jan;14(1):3-13.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>