Tioconazole-UK-20349-DataSheet-生命科學試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETioconazoleCat. No.: HY-B0319CAS No.: 65899-73-2Synonyms: UK-20349分式: CHClNOS分量: 387.71作靶點: Fungal作通路: Anti-infection儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 100 mg/mL (257.92 mM)H2O

2、 : 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (6.45 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.5 mg/mL (6.45 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (6.45 mM); Clea

3、r solutionBIOLOGICAL ACTIVITY物活性 Tioconazole (UK-20349)是抗真菌劑。IC50 & Target Antifungal 1.體外研究 Tioconazole (UK-20349) is an antifungal medication of the Imidazole class used to treat infections caused bya fungus or yeast. Tioconazole (UK-20349) topical (skin) preparations are also available for ringwo

4、rm, jockitch, athletes foot, and tinea versicolor or sun fungus. Tioconazole (UK-20349) interacts with 14-alphademethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component ofthe yeast membrane. In this way, Tioconazole (UK-20349) inhibits ergosterol synthesis, resulting inincreased cellular permeability 1.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fa