CCG-63802 - RGS Protein 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemECCG-63802Cat. No.: HY-70074CAS No.: 620112-78-9分式: CHNOS分量: 450.51作靶點(diǎn): RGS Protein作通路: GPCR/G Protein儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 1.67 mg/mL (3.71 mM; Need ultrasonic and

2、 warming)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.2197 mL 11.0985 mL 22.1971 mL5 mM - - -10 mM - - -請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) CCG-63802 is dissolved in DMSO and diluted with 0.9% NaCl3.BIOLOGICAL ACTIVITY物活性 CCG-63802可逆的G蛋信號(hào)調(diào)節(jié)（RGS）抑制劑，對(duì)RGS4抑制性尤其。戶使本產(chǎn)品發(fā)表的科研獻(xiàn)1/2 Mast

3、er of Small Molecules 您邊的抑制劑師www.MedChemE Inflammation. 2018 Dec;41(6):2079-2089.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Blazer LL, et al. Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins. Mol Pharmacol. 2010Sep;78(3):524-33.

4、2. Bosier B, et al. Inhibition of the regulator of G protein signalling RGS4 in the spinal cord decreases neuropathic hyperalgesia andrestores cannabinoid CB1 receptor signalling. Br J Pharmacol. 2015 Nov;172(22):5333-46.3. Meng X, et al. PPAR Agonist PGZ Attenuates OVA-Induced Airway Inflammation and Airway Remodeling via RGS4 Signaling in MouseModel. Inflammation. 2018 Jul 19.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;F