N-Acetyl-L-histidine-monohydrate-DataSheet-生命科學(xué)試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?Agonists?ScreeningLibrarieswww.MedChemEN-Acetyl-L-histidinemonohydrateCat.No.:HY-W014180CASNo.:39145-52-3分?式:C?H??N?O?分?量:215.21作?靶點:EndogenousMetabolite作?通路:MetabolicEnzyme/Protease儲存?式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實驗H2O:100mg/mL(464.66mM;Needultrasonic)DMSO:20mg/mL(92.93mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲備液1mM4.6466mL23.2331mL46.4662mL5mM0.9293mL4.6466mL9.2932mL10mM0.4647mL2.3233mL4.6466mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存?式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥?式選擇適當(dāng)?shù)娜芙?案，配制前請先配制澄的儲備液，再依次添加助溶劑(為保證實驗結(jié)果的可靠性，體內(nèi)實驗的?作液，建議您現(xiàn)?現(xiàn)配，當(dāng)天使?；澄的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分?指該溶劑在您配制終溶液中的體積占?)：1.請依序添加每種溶劑：10%DMSO>>40%PEG300>>5%Tween-80>>45%salineSolubility:≥2mg/mL(9.29mM);Clearsolution2.請依序添加每種溶劑：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥2mg/mL(9.29mM);Clearsolution3.請依序添加每種溶劑：10%DMSO>>90%cornoil1/2MasterofSmallMolecules—您?邊的抑制劑?師www.MedChemESolubility:≥2mg/mL(9.29mM);ClearsolutionBIOLOGICALACTIVITY?物活性N-Acetyl-L-histidinemonohydrate?種組氨酸衍?物，poikilothermic脊椎動物的?腦，視?膜和晶狀體中的重?物分?。N-Acetyl-L-histidinemonohydrate具有動物代謝物的作?。體外研究N-Acetyl-L-histidinemonohydrate(NAH)alsoexhibitsastrongphylogeneticcomponentinthatitisamajorosmolyteinthebrainandeyeofteleost(bony)fish,amphibiansandreptiles,butispresentinmuchloweramountsinbrainandothertissuesofhomeothermic(endothermic)vertebrates[1].REFERENCES[1].MorrisHBaslow,etal.N-acetyl-L-histidine,aProminentBiomoleculeinBrainandEyeofPoikilothermicVertebrates.Biomolecules.2015Apr24;5(2):635-46.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792