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第三十二章1腹腔鏡手術的麻醉Chapter32Anesthesia
forlaparoscopic
SurgeryThe
field
of
abdominal
surgeryhas
been
radically
changedwith
the
introduction
oflaparoscopy.2Recent
advance
in
robotic
and
video
technologyhave
made
the
use
of
laparoscopic
proceduresmore
widely
applicable.With
the
evolution
of
laparoscopy,a
substantialnumber
of
abdominal
procedures
are
beingperformed
using
this
approach,
includingcholecystectomy,
myomectomy,
and
soon.345Part
IPhysiological
changesduring
laparoscopic
surgeryThe
first
step
in
laparoscopy
isestablishment
of
pneumoperitoneum.The
ideal
insufflating gas
would
becolorless,
nonexplosive,Physiologically
inertand
readily
solubleinplasma.6Part
I7Physiological
changesduring
laparoscopic
surgeryCO2
is
used
extensively
in
clinic.Thespeed
and
pressure
of
thepneumoperitioneum
effect
theabsorption
of
CO2.Positioning
changes
will
effect
thephysiological
function.I. Cardiovascular
systemThe
pressure
of
pneumopertioneumeffect
three
aspects
.systemic vascular
resistance(SVR.
Afterloail).venous
return
(preload
).cardiac
function.8I. Cardiovascular
systemDuring
laparoscopic
cholecystectomyIf
intraabdominal
pressure
(IAP)
>10mmHg CVP
↑PAWP↑
SVR↑
CO
and
MAP↑If
intraabdominal
pressure
(IAP)
>20mmHgCVP
↓
SVR↑↑
CI CO↓
MAP↑↓or
normal9I. Cardiovascular
systemThe
cause
:Intraabdominal
positive
pressureintrathoracic
pressure
cardiacblood
flow
COIPPV
or
PEEP
intrathoracicpressure
CO10I. Cardiovascular
system11The
arrhythmias
during
laparoscopy
isapproximately
14%,Bradyarrhythemias
includingbradycardia,
nodal
rhythm
areattributed
to
a
vagal
response
due
torapid
insufflations.2.The
patients
were
placed
indifferent
body
position
(Table1)During
cholecystectomy
,
the
patientis
placed
on
head-up
about
10-20°.122.The
patients
were
placed
indifferent
body
position
(Table1)During
gynecological
surgery,
thepatient
is
placed
onhead-downposition.13Table-1
Hemodynamic
measurements
before
and
duringpneumoperitoneum(PP)during
laparoscopiccholecystectomy
in
healthy
patients14SupineHead-downHead-upSupinewithppHead-downwithppHead-upWith
ppHeartrate(beats/min)61±753
±466
±966
±1653
±370
±8MAP(mmHg)69
±776
±664
±
991
±1187
±884
±13CVP(mmHg)6.2
±2.910.2±3.50.8
±3.510.9±2.715.9±4.63.1
±2.6MPAP(mmHg)14.1±1.517.4±1.28.5
±3.518.4±3.720.0±6.110.8±2.5SVR(dynes/sec/cm5)1310±3021381±3131419±3421795±4441577±3442047±4303.
Carbon
dioxide
absorption15The
absorption
of
CO2
isinfluenced
significantly
byduration
of
interoperationinsufflationsIAP and
the
solubility
ofCO2
.3.
Carbon
dioxide
absorption16Hypercarbia
resulting
fromCO2
insufflations
has
direct
andindirect
homodynamic
effects.3.
Carbon
dioxide
absorptionThe
direct
effectsinclude
peripheralvasodilatation
and
depression
ofmyocardial
contractility.The
indirect
effects
include
activationof
the
central
nervous
system
andsympathizes
system,
which
increasemyocardial
contractility and
causestachycardia
and
hypertension17II.
Pulmonary
functionChanges
in
pulmonary
function
withpneumoperitoneum
:positioninganesthesiaElevation
of
diaphragm
maybeassociated
with
reduction
in
lungvolumes.18II.
Pulmonary
function
In
patients
undergoing
laparoscopic
procedure
with
15
degree
head-downtilt,
the
total
pulmonary
compliancedecreased
by
40%.with
20
degree
head-up
tilt,
thetotalpulmonary
compliance
decreased
by20%.19II.
Pulmonary
function20Increased
IAP
and
upwarddisplacement
of
the
diaphragmcan cause
alveolar collapse
andventilation/perfusionmismatching,resulting
in
hypoxemia
andhypercarbia.III. The
otherphysiological
changesIncreased
IAP
can
result
in
reductionin
splanchenic
and
renal
perfusion.Hepatic
blood
flow
is
decreased
.21III. The
other
physiologicalchangesReduction
in
urine
output.the
compression
of
renal
vesselincreased
plasma
renin
activity
.Increased IAP
can
result
inaspiration
and
regurgitation.22Part
IIAnesthesia
forlaparoscopic
surgery23Ⅰ. Preoperative
evaluation
andpreparation
for
anesthesia.1.
EvaluationElderly,
obesity,
hypertension,coronary
artery
disease.Serious
hypertension
,
cardiacdysfunction
, COPD
.The
open
surgery
(opencholecystectomy)
duo
to
medicalproblem
(serious
hypercarbia).24Ⅰ.
Preoperative
evaluation
andpreparation
for
anesthesia.2.
Preparation
and
premedicationSame
as
general
surgery.Meperidine
and
opioid
is
thought
tocausesphincter
of
oddi
spasm.Atropine
may
help
decease
spasm.H2
antagonist
(ranitidine)
may
be
given(the
patient
being
at
risk for
gastricaspiration).To
open
upper
extremity
vein.25Ⅱ.The
choice
of
anesthesia1.The
principle
of
choiceThe
principle
is
rapidly,
shorter,safety
comfortable
and
return
to
anormal
activity
early.General
anesthesia
is
may
bemoresuitable
than other
anesthesia.26Ⅱ.The
choice
of
anesthesia2.Method
of
anenthesiaA. General
anesthesiaAdvantage:①Proper
depths
of
anesthesia.②
Effective
ventilation.③
To
control
the
relax
of
muscle.④
Adjusting
MVV.27Ⅱ.The
choice
of
anesthesiaAnesthetic
ManagementThe
endotracheal
intubation
issuggested.An
oral
gastric
tube
should
beinserted
to
ensure
that
gastricdistension
does
not
exist.28Ⅱ.The
choice
of
anesthesiaAnesthetic
agents.Propofol,
Etomidate,
Midazolam.Fentanyl,
Remifentanyl,Succinyicholine
Vecuronium
Atracurium.Isoflurane,
desflurane.The
use
of
N2O
is
controversial.It
increases
bowel
distention,
and
produceconflicting
results
on
the
rate
of
N2O
onpostoperative
nausea.29Ⅱ.The
choice
of
anesthesiaB.Epidural
anesthesia。A
high
level
is
required
for
completemuscle
relaxation。70prevent
diaphragmatic
irritationcaused
by
gas
insufflationandsurgical
manipulations.30Ⅱ.The
choice
of
anesthesiaB.Epidural
anesthesia。Serious
respiratorg
depression
ispossiblea
high
regional
blockthe
use
ofopioidthe
diaphragm
is
rised
duringinsufflation.The
occasional
occurrence
of
referredshoulder
pain31Ⅱ.The
choice
of
anesthesia32C.
General
Aesthesia
and
Epiduralanesthesia.D.
Regional
anesthesia.Ⅲ.Perioprative
monitoring33Cardiovascular
functionRespiratory
functionUrinary
volumeNeuromuscular
transmissionⅣ.Special
considerations
inthe
anesthesia34Control
ofintra-abdominalpressurelaparoscopic
cholecystetomy,
IAP10-15mmHgPrevention
of
aspiration
of
gastriccontents.Gynecologic
laparoscopy,IAP20-40mmHg*
obesity,abdominal
wall
lift
isusedⅣ.Special
considerations
inthe
anesthesia35PositionLaparoscopic
cholecystetomy
,supine
is
placed,reverse
trendelenburgwith
right
side
elevates.Gynecologic
laparoscopy,
head-down
andfeet-up.Ⅳ.Special
considerations
inthe
anesthesia36Enhance
respiratory
managementduring
operationThe
use
of
neuromuscularblockers
and
complete
musclerelaxation are
requiredⅣ.Special
considerations
inthe
anesthesia37If
it
is
not
possible
to
complete
thelaparoscopic
procedure,
for
example:
a
majorabdominal vessel
lacerated,peritonitis
and
hemorrhage,
a
opensurgery
will
be
performed.Ⅳ.Special
considerations
inthe
anesthesia38Epidural
anesthesia
representalternative
for
laparoscopic
surgery.But
a
high
level
is
required.
Adisadvantage
is
the
occurrence
ofreferred
shoulder
pain.Ⅳ.Special
considerations
inthe
anesthesiaAfter
operation,
the
residualpheumoperitoneum
should
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