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Self-introductionOfDoctoralReexaminationMaster'sSpecialty:XXXXXEngineeringApplicationdirection:XXXXXApplicant:XXXResearchdirection:XXXXXXXXXXX1CONTENTS1.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanning2PersonalIntroduction0131.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningPersonalIntroductionDateofbirth:2023/5/14Hometown:BeijingPoliticalprofile:PartymembershipName:XXXXEnglishlevel:CET6:62041.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningEducationUndergraduatelevelMaster'slevel20XX.09~20XX.07XXXXUniversityFacultyofComputerScience-XXXXmajorNo.1inthemajor20XX.09~20XX.07XXXXUniversityFacultyofComputerScience-XXXXmajorNo.1inthemajor51.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningScientificskills01EnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText02EnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText03EnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText04EnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText61.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningAwards2017~2018NationalInspirationalScholarship2018FirstClassScholarshipXXProvinceXXXXXXCompetitionFirstPrize2017~2018NationalInspirationalScholarship2018FirstClassScholarshipXXProvinceXXXXXXCompetitionFirstPrize71.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningWorkexperienceEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextSeptember1997-June2002September1997-September2002September2002toDecember2004EnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText8MainAcademicAchievements0291.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningResearchresults(1)ResearchonXXXXXXXXXXXXXXXXXXPleaseaddtitlecontenthere

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Pleasehere101.PersonalIntroduction2.MainAcademicAchievementsResearchresults3.DoctoralResearchPlanningTopicPeriodicalSourceRankState[1]XXXXXXXXXXXXXXXXXSCI(JCR:Q2IF:4.678)firstXXX[2]XXXXXXXXXXXXXXXXXSCI(JCR:Q2IF:4.678)firstXXX[3]XXXXXXXXXXXXXXXXXSCI(JCR:Q2IF:4.678)firstXXX[4]XXXXXXXXXXXXXXXXXSCI(JCR:Q2IF:4.678)firstXXX[5]XXXXXXXXXXXXXXXXXSCI(JCR:Q2IF:4.678)firstXXX111.PersonalIntroduction2.MainAcademicAchievementsMainAcademicAchievements3.DoctoralResearchPlanningPleaseaddtitlecontenthere

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Pleaseaddtitlecontenthere121.PersonalIntroduction2.MainAcademicAchievementsMainAcademicAchievements3.DoctoralResearchPlanningPleaseaddtitlecontenthere

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Pleaseaddtitlecontent131.PersonalIntroduction2.MainAcademicAchievementsMainAcademicAchievements3.DoctoralResearchPlanningClicktoenterkeywords01PleaseaddtitlecontentherePleaseaddtitlecontentGrantnumber:XXXXXXXXXXXXX02PleaseaddtitlecontentherePleaseaddtitlecontentGrantnumber:XXXXXXXXXXXXX03PleaseaddtitlecontentherePleaseaddtitlecontentGrantnumber:XXXXXXXXXXXXX141.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningMainAcademicAchievementsClicktoenterkeywordsClicktoenterkeywordsEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextClicktoenterkeywordsEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextClicktoenterkeywordsEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText15DoctoralResearchPlanning03161.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningDoctoralResearchPlanningEnterTextEnterTextEnterEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText

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EnterTextEnterTextEnterTextEnterText171.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningDoctoralResearchPlanningExpectedResults:1.Pleaseaddtitlecontenthere

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PleasehereAccumulationfoundationofmaster'slevel:1.Dataanalysisability2.Testoperationability3.Textwritingability4.Abilitytoreportresults2.Pleaseaddtitlecontenthere

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Pleasehere181.PersonalIntroduction2.MainAcademicAchievements3.DoctoralResearchPlanningDoctoralResearchPlanningEnterTextEnterTextEnterEnterTextEnterTextEnterTextEnterTextEnterTextEnterTextEnterText

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YOUMaster'sSpecialty:XXXXXEngineeringApplicationdirection:XXXXXApplicant:XXXResearchdirection:XXXXXXXXXXX21Self-introductionOfDoctoralReexaminationCandidate:XXXXXApplying

Major:XXXXXXXXXXX1.Personalintroduction2.EducationExperience3.MasterResearch4.DoctoralResearchPlanCONTENTS1.Personalintroduction1、PersonalintroductionName:MaDongmeiDateofbirth:1998/09/09PoliticalAppearance:PartyMemberMajor:ComputermajorFaculty:SchoolofComputerandComputingGender:FemaleHometown:BeijingSchool:FudanUniversity2.EducationExperience2.1、EducationExperiencePeriodMajordegreeSchool2014.09-2020.07BiologicalEngineeringbachelordegreePekingUniversity2020.09-MicrobialandbiochemicalpharmacyMasterdegreePekingUniversity2.2、Awards2020NationalScholarshipforMaster'sStudents2021NationalScholarshipforPostgraduateStudentsOutstandinggraduatesofFudanUniversityin20222.3、EducationExperienceTraditionalChineseMedicineBureauofGuangdongProvince(NO.20141065),NaturalScienceFoundationofGuangdongProvince(NO.2017A32217007)NationalUniversityStudentInnovationProgram3.MasterResearch3、MasterResearchPTBP1enhancesexon11askippinginMenapre-mRNAtopromotemigrationandinvasioninlungcarcinomacellsBackgroundObjectivesTechnologyMethodsResultsConclusions3.1、BackgroundSevenalternativesplicing(AS)subgroups:ExonSkippingAccountsForNearly40%OfASEvents;Alternative3′SpliceSite(3′SS)Selection(18.4%)And5′SSSelection(7.9%);IntronRetentionAccountsForLessThan5%;MutuallyExclusiveExons,AlternativePromoterUsage(3′utr)AndAlternativePolyadenylation(5′utr)AreNotFrequent.3.2、ObjectivesRegulatedbyPTBP1?TheexactmechanismmediatedMenaAShasnotbeenelucidated.ThepurposeofthisstudyistoexplorethemolecularmechanismofPTBP1inregulatingMenaalternativesplicingandroleofPTBP1inlungcarcinomacellsmetastasis.3.3、TechnologyMethodsPleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontentherePleaseaddtitlecontentherePleaseaddtitlecontentherePleaseaddcontenthere3.4、ResultsPTBP1ishighlyexpressedinlungadenocarcinoma(LUAD)tissuesand95-DcellsandupregulationofPTBP1isassociatedwithEMTprogressPTBP1promotesmigrationandinvasionoflungcancercellsPTBP1enhancesexon11askippingofMenapre-mRNAinlungcancercellsPTBP1-mediatedmigrationandinvasionof95-DcellsarepartiallydependentonMenaINV4.DoctoralResearchPlan4、DoctoralResearchPlanEarlygoalstudyhard,improveeveryday.studyhard,improveeverydayMedium-termGoalstudyhard,improveeveryday.studyhard,improveeverydaystudyhard,improveeveryday.studyhard,improveeverydayLateGoal4

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