Mulberroside-A-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEMulberrosideA(Standard)Cat.No.:HY-N0619RCASNo.:102841-42-9分?式:C??H??O??分?量:568.52作?靶點(diǎn):TNFReceptor;InterleukinRelated;Tyrosinase作?通路:Apoptosis;Immunology/Inflammation;MetabolicEnzyme/Protease儲(chǔ)存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性MulberrosideA(Standard)MulberrosideA的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。MulberrosideA(MorusalbaL.)中的主?物活性成分之?[1]。MulberrosideA可降低TNF-α，IL-1β和IL-6的表達(dá)，抑制NALP3，caspase-1和NF-κB的激活以及ERK，JNK和p38的磷酸化。MulberrosideA具有抗炎和抗細(xì)胞凋亡作?[2]。MulberrosideA對(duì)蘑菇酪氨酸酶(tyrosinase)具有抑制活性，IC50為53.6μM[3]。REFERENCES[1].MeiM,etal.InvitropharmacokineticcharacterizationofmulberrosideA,themainpolyhydroxylatedstilbeneinmulberry(MorusalbaL.),anditsbacterialmetaboliteoxyresveratrolintraditionaloraluse.JAgricFoodChem.2012Mar7;60(9):2299-308.[2].WangCP,etal.MulberrosideAprotectsagainstischemicimpairmentinprimarycultureofratcorticalneuronsafteroxygen-glucosedeprivationfollowedbyreperfusion.JNeurosciRes.2014Jul;92(7):944-54.[3].KimJK,etal.BiotransformationofmulberrosideAfromMorusalbaresultsinenhancementoftyrosinaseinhibition.JIndMicrobiolBiotechnol.2010Jun;37(6):631-7.[4].Cai-PingWang,etal.Mulberrosideapossessespotenturicosuricandnephroprotectiveeffectsinhyperuricemicmice.PlantaMed.2011May;77(8):786-94.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792/p>