Deoxynivalenol-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEDeoxynivalenol(Standard)Cat.No.:HY-N6684RCASNo.:51481-10-8分子式:C??H??O?分子量:296.32作用靶點(diǎn):Others;Others作用通路:Others儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Deoxynivalenol(Standard)是Deoxynivalenol的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Deoxynivalenol是單端孢菌素家族(trichothecenesfamily)中一種具有口服活性的真菌毒素，通過緊密連接處的細(xì)胞旁路來穿過腸粘膜。Deoxynivalenol轉(zhuǎn)運(yùn)不受P-糖蛋白(PgP)或多藥耐藥相關(guān)蛋白(MRPs)抑制劑的影響[1]。REFERENCESSergentT,etal.DeoxynivalenoltransportacrosshumanintestinalCaco-2cellsanditseffectsoncellularmetabolismatrealisticintestinalconcentrations.ToxicolLett.2006Jul1;164(2):167-76.DiesingAK,etal.Mycotoxindeoxynivalenol(DON)mediatesbiphasiccellularresponseinintestinalporcineepithelialcelllinesIPEC-1andIPEC-J2.ToxicolLett.2011Jan15;200(1-2):8-18.CollinsTF,etal.Effectsofdeoxynivalenol(DON,vomitoxin)oninuterodevelopmentinrats.FoodChemToxicol.2006Jun;44(6):747-57.PestkaJJ,etal.Immunochemicalassessmentofdeoxynivalenoltissuedistributionfollowingoralexposureinthemouse.ToxicolLett.2008May5;178(2):83-7.ForsellJH,etal.Comparisonofacutetoxicitiesofdeoxynivalenol(vomitoxin)and15-acetyldeoxynivalenolintheB6C3F1mouse.FoodChemToxicol.1987Feb;25(2):155-62.SergentT,etal.DeoxynivalenoltransportacrosshumanintestinalCaco-2cellsanditseffectsoncellularmetabolismatrealisticintestinalconcentrations.ToxicolLett.2006Jul1;164(2):167-76.DiesingAK,etal.Mycotoxindeoxynivalenol(DON)mediatesbiphasiccellularresponseinintestinalporcineepithelialcelllinesIPEC-1andIPEC-J2.ToxicolLett.2011Jan15;200(1-2):8-18.CollinsTF,etal.Effectsofdeoxynivalenol(DON,vomitoxin)oninuterodevelopmentinrats.FoodChemToxicol.2006Jun;44(6):747-57.PestkaJJ,etal.Immunochemicalassessmentofdeoxynivalenoltissuedistributionfollowingoralexposureinthemouse.ToxicolLett.1/2 MasterofBioactiveMolecules—您身邊的抑制劑大師www.MedChemE2008May5;178(2):83-7.ForsellJH,etal.Comparisonofacutetoxicitiesofdeoxynivalenol(vomitoxin)and15-acetyldeoxynivalenolintheB6C3F1mouse.FoodChemToxicol.1987Feb;25(2):155-62.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchu