Arg-AMS _Aminoacyl-tRNA Synthetase 抑制劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEArg-AMSCat. No.: HY-112862CAS No.: 301351-95-1分式: CHNOS分量: 502.51作靶點: Aminoacyl-tRNA Synthetase作通路: Metabolic Enzyme/Protease儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 100 mg/mL (199.0

2、0 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 1.9900 mL 9.9501 mL 19.9001 mL5 mM 0.3980 mL 1.9900 mL 3.9800 mL10 mM 0.1990 mL 0.9950 mL 1.9900 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢埾扰渲瞥吻宓膬湟?，再依次添加助溶?為保證實驗結(jié)果的可靠性，

3、體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (4.98 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (4.98 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oil

4、1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.5 mg/mL (4.98 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Arg-AMS精氨酸 tRNA 合成酶 (arginyl tRNA synthetase) 的有效抑制劑，能夠和核糖體多肽合成酶的 A 結(jié)構(gòu)域緊密結(jié)合。REFERENCES1. Kasai S, et al. Functional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based proteinprofiling. Chem Commun (Camb). 2015 Nov 11;51(87):15764-7.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;