Aloe-emodin-Rhabarberone-DataSheet-生命科學試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEAloe emodinCat. No.: HY-N0189CAS No.: 481-72-1Synonyms: Rhabarberone; 3-Hydroxymethylchrysazine分式: CHO分量: 270.24作靶點: Autophagy作通路: Autophagy儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 Ethanol

2、: 1 mg/mL (3.70 mM; Need ultrasonic and warming)DMSO : 1 mg/mL (3.70 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.7004 mL 18.5021 mL 37.0041 mL5 mM - - -10 mM - - -請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 蘆薈黃素(Aloe emodin)是從蘆薈葉中提取出的羥基蒽醌，已被證明體外和體內(nèi)

3、抗腫瘤活性。REFERENCES1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE1. Huang PH, et al. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER Inhibition. Evid Based ComplementAlternat Med. 2013;2013:376123.2. Liu K, et al. Aloe-emodin suppresses prostate cancer by targeting the mT

4、OR complex 2. Carcinogenesis. 2012 Jul;33(7):1406-11.3. Li SW, et al. Antiviral activity of aloe-emodin against influenza A virus via galectin-3 up-regulation. Eur J Pharmacol. 2014 Sep5;738:125-32.4. Suboj P, et al. Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reducedDNA binding activity of NF-B. Eur J Pharm Sci. 2012 Apr 11;45(5):581-91.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;