Bay-59-3074 - Cannabinoid Receptor Agonist - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBay 59-3074Cat. No.: HY-100488CAS No.: 406205-74-1分式: CHFNOS分量: 453.36作靶點: Cannabinoid Receptor作通路: GPCR/G Protein; Neuronal Signaling儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 34 mg/m

2、L (75.00 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.2058 mL 11.0288 mL 22.0575 mL5 mM 0.4412 mL 2.2058 mL 4.4115 mL10 mM 0.2206 mL 1.1029 mL 2.2058 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Bay 59-3074個新的，有選擇性的CB1/CB2 受體

3、的激動劑，Ki值在CB1和CB2中的KI值分別是48.3 nM和45.5 nM。REFERENCES1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE1. De Vry J et al. 3-2-cyano-3-(trifluoromethyl)phenoxyphenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): a novelcannabinoidCb1/Cb2 receptor partial agonist with antihyperalgesic and antiallodynic

4、 effects. J Pharmacol Exp Ther. 2004 Aug;310(2):620-322. De Vry J et al. Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in therat. Eur J Pharmacol. 2004 Nov 28;505(1-3):127-33.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021