6-Maleimidocapronic-acid-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE6-Maleimidocapronic acidCat. No.: HY-77959CAS No.: 55750-53-3分式: CHNO分量: 211.21作靶點(diǎn): PROTAC Linker作通路: PROTAC儲存式: 4C, stored under nitrogen* In solvent : -80C, 6 months; -20C, 1 month (stored undernitrogen)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 200 mg

2、/mL (946.92 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 4.7346 mL 23.6731 mL 47.3462 mL5 mM 0.9469 mL 4.7346 mL 9.4692 mL10 mM 0.4735 mL 2.3673 mL 4.7346 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 6-Maleimidocapronic acid種 PROTAC linker，屬于 alkyl c

3、hain 類?？捎诤铣?PROTAC 分 1。IC50 & Target Alkyl-Chain(批量添加)體外研究 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase andthe other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system toselectively degrade target protei

4、ns 1.1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEREFERENCES1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs.EBioMedicine. 2018 Oct;36:553-562McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021-