Carboprost-tromethamine-DataSheet-生命科學試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemECarboprost tromethamineCat. No.: HY-A0195CAS No.: 58551-69-2分式: CHNO分量: 489.64作靶點: Prostaglandin Receptor作通路: GPCR/G Protein儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 H2O : 125 mg/mL (255.29

2、mM; Need ultrasonic)DMSO : 100 mg/mL (204.23 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.0423 mL 10.2116 mL 20.4232 mL5 mM 0.4085 mL 2.0423 mL 4.0846 mL10 mM 0.2042 mL 1.0212 mL 2.0423 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥式選擇適當?shù)娜芙獍福渲魄罢埾扰渲瞥蔚膬湟?，?/p>

3、依次添加助溶劑(為保證實驗結果的可靠性，體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當天使；澄的儲備液可以根據(jù)儲存條件，適當保存；以下溶劑前的百分指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (5.11 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (5.11 mM); Clear solution3. 請依序添加每種溶劑： 10%

4、 DMSO 90% corn oil1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.5 mg/mL (5.11 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Carboprost tromethamine前列腺素 F2 (prostaglandin F2) 的 15 甲類似物。Carboprosttromethamine 能有效促進宮規(guī)律性收縮，顯著減少產(chǎn)后出量。體內(nèi)研究 Carboprost tromethamine has a significant effect on th

5、e prevention of postpartum hemorrhage in cesareansection, and has a significant effect on improving the state of hypercoagulable blood and maintaining thestable hemodynamic state. Carboprost tromethamine has been accounted for to be 84-96% successful in thetreatment of persistent hemorrhage because

6、of uterine atony 1.REFERENCES1. Ling Z, et al. Effect of carboprost tromethamine in prevention of postpartum hemorrhage in cesarean section. Pak J Pharm Sci. 2018Sep;31(5(Special):2257-2262.2. Bai J, et al. A comparison of oxytocin and carboprost tromethamine in the prevention of postpartum hemorrhage in high-risk patientsundergoing cesarean delivery. Exp Ther Med. 2014 Jan;7(1):46-50. Epub 2013 Nov 1.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Te