星形細(xì)胞瘤-基礎(chǔ)醫(yī)學(xué)-醫(yī)藥衛(wèi)生-專業(yè)資料課件

Lecturer:

GuoXiang

ClassificationandDiagnosisofastrocytoma(星形細(xì)胞瘤)Lecturer:GuoXiangClassificaMorbidityofAstrocytomaAstrocytictumor78%GliomaPrimarybraintumor40%5-10100000MorbidityMorbidityofAstrocytomaAstrocTypeofAstrocytomaWHOclassificationⅠ~ⅣⅠ級毛細(xì)胞型星形細(xì)胞瘤、室管膜下巨細(xì)胞星形細(xì)胞瘤Ⅱ級彌漫型星形細(xì)胞瘤Ⅲ級間變型星形細(xì)胞瘤Ⅳ級膠質(zhì)母細(xì)胞瘤PilocyticastrocytomaANDSubependymalgiantcellastrocytomasDiffuseastrocytoma

Anaplasticastrocytoma

GlioblastomaTypeofAstrocytomaWHOclassifSubependymalgiantcellastrocytomas-GradeⅠReddish-yellowpimpleschromosomaldisorder染色體疾病epiloia（結(jié)節(jié)性硬化）8Y~18Y(male-to-femaleratio=3:1)subependymalnodulescontrast-enhancehydrocephalus腦積水favorableclinicaloutcome紅黃色丘疹SubependymalgiantcellastrocT1T2T1-enhanceCTnon-contrastM16yT1T2T1-enhanceCTnon-contrastPilocyticastrocytoma-GradeⅠChildrenCerebellumhemispheresorvermisSolidandcysticpartNormaltissue>solidnodule>cysticmass>CSFindensityonNCCTMRI:ahigh-signal-intensitycystsurroundingaiso-intensitymuralnoduleonT2ContrastenhancementwithbothCTandMRIvermisPilocyticastrocytoma-GradeⅠF62Y

T1T2T1-enhanceF62YT1T2T1-enhancePathologyPathology彌漫型星形細(xì)胞瘤屬于交界性腫瘤，容易復(fù)發(fā)，且惡性度有不斷增加的趨勢，最終發(fā)展為膠質(zhì)母細(xì)胞瘤。Grade-ⅡDiffuseastrocytoma

Grade-ⅢAnaplasticastrocytomaGrade-ⅣGlioblastoma

Diffuseastrocytoma-GradeⅡ

borderlinetumorsurgerymalignancywillbehigherrecurCharacteristic彌漫型星形細(xì)胞瘤屬于交界性腫瘤，容易復(fù)發(fā)，且惡性度有不斷增加ImagingCharacteristicBrainstemorsupratentorialwhitematterpoorlydefinedborderLow-densityonCTslightly>CSFNosignificantenhancementImagingCharacteristicBrainstNoorslightlyenhancementCysticchangeT1WIhypointensitysignalT2WIhyperintensitysignalF54YNoorslightlyenhancementCystSurgicalfieldandSpecimen

Thetumorshoweddiffuselyinfiltratedgrowing.NOhemorrhageandnecrosis.SurgicalfieldandSpecimenTAnaplasticastrocytoma-GradeⅢthetumorenhanceddistinctlyAnaplasticastrocytoma-GradeⅢtT1-enhanceFLAIRT1T2T1Glioblastoma-Grade-ⅣAdulthoodMixeddensityorsignallesionHemorrhageandnecrosisContrast-enhanceT1-enhanceFLAIRT1T2T1Glioblast星形細(xì)胞瘤_基礎(chǔ)醫(yī)學(xué)_醫(yī)藥衛(wèi)生_專業(yè)資料課件Becausethetreatmentofastrocytomaismainlybasedonpathologicaltype,soitwillbeveryhelpfultomakeanaccuratediagnos