Allylthiourea-Standard-生命科學試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEAllylthiourea(Standard)Cat.No.:HY-B0543RCASNo.:109-57-9分?式:C?H?N?S分?量:116.18作?靶點:ReactiveOxygenSpecies作?通路:Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Allylthiourea(Standard)Allylthiourea的分析標準品。本產(chǎn)品?于研究及分析應?。Allylthiourea能選擇性抑制氨的氧化。Allylthiourea通常?于抑制硝化，通過靶向氨單加氧酶作?并螯合活性位點中的銅來抑制其活性。Allylthiourea還具有抗癌活性，對MCF-7細胞系具有細胞毒性，IC50為5.22mM。Allylthiourea可?于微污染物?物降解性與癌癥領域研究[1][2][3][4]。REFERENCES[1].Ginestet,P.,etal.,Estimationofnitrifyingbacterialactivitiesbymeasuringoxygenuptakeinthepresenceofthemetabolicinhibitorsallylthioureaandazide.ApplEnvironMicrobiol,1998.64(6):p.2266-8.[2].Yu,Y.,J.A.Ramsay,andB.A.Ramsay,Useofallylthioureatoproducesolublemethanemonooxygenaseinthepresenceofcopper.ApplMicrobiolBiotechnol,2009.82(2):p.333-9.[3].TatariK,etal.Challengesinusingallylthioureaandchlorateasspecificnitrificationinhibitors[J].Chemosphere,2017,182:301-305.[4].WidiandaniT,etal.NewN-allylthioureaderivatives:synthesis,moleculardockingandinvitrocytotoxicitystudies[J].TropicalJournalofPharmaceuticalResearch,2018,17(8):1607-1613.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:0