Dequalinium-Chloride-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEDequaliniumChloride(Standard)Cat.No.:HY-B0567RCASNo.:522-51-0分子式:C??H??Cl?N?分子量:527.57作用靶點(diǎn):PotassiumChannel;nAChR;Apoptosis;Bacterial;Parasite作用通路:MembraneTransporter/IonChannel;NeuronalSignaling;Apoptosis;Anti-infection儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Dequalinium(Chloride)(Standard)是Dequalinium(Chloride)的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。DequaliniumChloride是Apamin(HY-P0256)敏感型的鉀離子通道選擇性阻斷劑。DequaliniumChloride是一種陽離子、親脂性線粒體毒物。REFERENCESKramer,W.,[Treatmentoftonsillitiswithdequaliniumchloride].FortschrMed,1977.95(16):p.1108-10.Gamboa-Vujicic,G.,etal.,Toxicityofthemitochondrialpoisondequaliniumchlorideinamurinemodelsystem.JPharmSci,1993.82(3):p.231-5.Belanger-CoastMG,etal.Dequaliniumchlorideisanantagonistsofα7nicotinicacetylcholinereceptors.EurJPharmacol.2022Jun15;925:175000.MendlingW,etal.Useoflocallydelivereddequaliniumchlorideinthetreatmentofvaginalinfections:areview.ArchGynecolObstet.2016Mar;293(3):469-84.CastleNA,etal.Dequalinium:apotentinhibitorofapamin-sensitiveK+channelsinhepatocytesandofnicotinicresponsesinskeletalmuscle.EurJPharmacol.1993May19;236(2):201-7.BugayV,etal.EffectsofSublethalOrganophosphateToxicityandAnti-cholinergicsonElectroencephalogramandRespiratoryMechanicsinMice.FrontNeurosci.2022May2;16:866899.AbdulM,etal.Expressionandactivityofpotassiumionchannelsinhumanprostatecancer.CancerLett.2002Dec1;186(1):99-105.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021