Isoxsuprine-hydrochloride-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEIsoxsuprinehydrochloride(Standard)Cat.No.:HY-B1270RCASNo.:579-56-6分?式:C??H??ClNO?分?量:337.84作?靶點(diǎn):AdrenergicReceptor;iGluR作?通路:GPCR/GProtein;NeuronalSignaling;MembraneTransporter/IonChannel儲(chǔ)存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Isoxsuprinehydrochloride(Standard)Isoxsuprinehydrochloride的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Isoxsuprinehydrochlorideβ腎上腺素受體激動(dòng)劑，對(duì)于?宮肌層和胎盤的β腎上腺素受體的Ki值分別為13.65μM和3.48μM。Isoxsuprinehydrochloride也?種NMDA受體拮抗劑。IC50&TargetKi:13.65μΜ(myometrialbeta-adrenergicreceptor),3.48μΜ(placcntalbeta-adrenergicreceptor)[1]NMDAreceptor[3]REFERENCES[1].FalkayG,etal.Affinityoftocolyticagentsonhumanplacentalandmyometrialbeta-adrenergicreceptors.JPerinatMed.1986;14(2):109-13.[2].KretschyN,etal.Invitroinhibitionofbreastcancerspheroid-inducedlymphendothelialdefectsresemblingintravasationintothelymphaticvasculaturebyacetohexamide,isoxsuprine,nifedipinandproadifen.BrJCancer.2013Feb19;108(3):570-8.[3].HillJW,etal.Identificationofisoxsuprinehydrochlorideasaneuroprotectantinischemicstrokethroughcell-basedhigh-throughputscreening.PLoSOne.2014May7;9(5):e96761.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:02