L-Ascorbic-acid-sodium-salt-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEL-Ascorbicacidsodiumsalt(Standard)Cat.No.:HY-B0166ARCASNo.:134-03-2分子式:C?H?NaO?分子量:198.11作用靶點(diǎn):CalciumChannel;ReactiveOxygenSpecies;Apoptosis;EndogenousMetabolite作用通路:MembraneTransporter/IonChannel;NeuronalSignaling;Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB;Apoptosis儲存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 L-Ascorbicacid(sodiumsalt)(Standard)是L-Ascorbicacid(sodiumsalt)的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。L-Ascorbicacidsodiumsalt(Sodiumascorbate)，一種電子供體，是一種內(nèi)源性抗氧化劑。L-Ascorbicacidsodiumsalt選擇性抑制Cav3.2通道(Cav3.2channels)，IC50為6.5μM。L-Ascorbicacidsodiumsalt還是一種膠原沉積促進(jìn)劑和彈性生成抑制劑。REFERENCESHinekA,etal.SodiumL-ascorbateenhanceselasticfibersdepositionbyfibroblastsfromnormalandpathologichumanskin.JDermatolSci.2014Sep;75(3):173-82.YangX,etal.MousemelanomacelllineB16F10-derivedconditionedmediuminhibitssodiumL-ascorbate-inducedB16F10cellapoptosis.NanFangYiKeDaXueXueBao.2012Feb;32(2):146-50.MorimuraK,etal.LackofurinarybladdercarcinogenicityofsodiumL-ascorbateinhumanc-Ha-rasproto-oncogenetransgenicrats.ToxicolPathol.2005;33(7):764-7.TakagiH,etal.Limitedtumor-initiatingactivityofphenylethylisothiocyanatebypromotionwithsodiumL-ascorbateinarattwo-stageurinarybladdercarcinogenesismodel.CancerLett.2005Mar10;219(2):147-53.AleksanderHinek,etal.SodiumL-ascorbateenhanceselasticfibersdepositionbyfibroblastsfromnormalandpathologichumanskin.JDermatolSci.2014Sep;75(3):173-82.MichaelTNelson,etal.Molecularmechanismsofsubtype-specificinhibitionofneuronalT-typecalciumchannelsbyascorbate.JNeurosci.2007Nov14;27(46):12577-83.McePdfHeight1/1 MasterofBioactiveMolecules—您身邊的抑制劑大師www.MedChemECaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-8