Promethazine-hydrochloride-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEPromethazinehydrochloride(Standard)Cat.No.:HY-B0781RCASNo.:58-33-3分子式:C??H??ClN?S分子量:320.88作用靶點:HistamineReceptor;mAChR;AdrenergicReceptor作用通路:GPCR/GProtein;Immunology/Inflammation;NeuronalSignaling儲存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Promethazine(hydrochloride)(Standard)是Promethazine(hydrochloride)的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Promethazinehydrochloride是一種具有口服活性的吩噻嗪衍生物，具有抗組胺(H1)、鎮(zhèn)靜、止吐、抗膽堿能和抗暈動病特性。Promethazinehydrochloride是H1受體強效拮抗劑和mAChR拮抗劑，對5-HT2A和5-HT2C受體也有一定的親和性[1][2]。REFERENCESFiorellaD,etal.Theroleofthe5-HT2Aand5-HT2Creceptorsinthestimuluseffectsofhallucinogenicdrugs.I:Antagonistcorrelationanalysis.Psychopharmacology(Berl).1995Oct;121(3):347-56.KasaiT,etal.PromethazineHydrochlorideInhibitsEctopicFatCellFormationinSkeletalMuscle.AmJPathol.2017Dec;187(12):2627-2634.McDonoughJA,etal.Microcapsule-gelformulationofpromethazineHClforcontrollednasaldelivery:amotionsicknessmedication.JMicroencapsul.2007Mar;24(2):109-16.WinkCS,etal.EffectsofpromethazineHClonosteoporoticfemoraofadultcastratedmalerats.ActaAnat(Basel).McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021-