Raltegravir-potassium-Standard-生命科學試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemERaltegravirpotassium(Standard)Cat.No.:HY-10353ARCASNo.:871038-72-1分子式:C??H??FKN?O?分子量:482.51作用靶點:HIVIntegrase;HIV作用通路:MetabolicEnzyme/Protease;Anti-infection儲存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Raltegravir(potassium)(Standard)是Raltegravir(potassium)的分析標準品。本產(chǎn)品用于研究及分析應用。Raltegravir(MK0518)potassium是一種有效的integrase抑制劑，用于研究HIV感染。REFERENCESHare,S.,etal.,Molecularmechanismsofretroviralintegraseinhibitionandtheevolutionofviralresistance.ProcNatlAcadSciUSA,2010.107(46):p.20057-62.HicksC,etal.Raltegravir:thefirstHIVtype1integraseinhibitor.ClinInfectDis.2009Apr1;48(7):931-9MossDM,etal.DivalentmetalsandpHalterraltegravirdispositioninvitro.AntimicrobAgentsChemother.2012Jun;56(6):3020-6HareS,etal.Structuralandfunctionalanalysesofthesecond-generationintegrasestrandtransferinhibitordolutegravir(S/GSK1349572).MolPharmacol.2011Oct;80(4):565-72.Lewis,M.G.,etal.Responseofasimianimmunodeficiencyvirus(SIVmac251)toraltegravir:abasisforanewtreatmentforsimianAIDSandananimalmodelforstudyinglentiviralpersistenceduringantiretroviraltherapy.Retrovirology,2010.7:p.21.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:0