Sinomenine-hydrochloride-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemESinomeninehydrochloride(Standard)Cat.No.:HY-15122ARCASNo.:6080-33-7分?式:C??H??ClNO?分?量:365.85作?靶點(diǎn):NF-κB;OpioidReceptor;Autophagy;Apoptosis作?通路:NF-κB;GPCR/GProtein;NeuronalSignaling;Autophagy;Apoptosis儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Sinomeninehydrochloride(Standard)Sinomeninehydrochloride的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Sinomeninehydrochloride(Cucolinehydrochloride)來?Sinomeniumacutum的?種?物堿，是NF-κB活化的阻斷劑[1]。Sinomenine也μ阿?受體(μ-opioidreceptor)激活劑[2]。IC50&TargetNF-κB[1],μ-opioidreceptor[2]REFERENCES[1].SongL,etal.SinomenineinhibitsbreastcancercellinvasionandmigrationbysuppressingNF-κBactivationmediatedbyIL-4/miR-324-5p/CUEDC2axis.BiochemBiophysResCommun.2015Aug28;464(3):705-10.[2].GaoT,etal.Analgesiceffectofsinomenineinrodentsafterinflammationandnerveinjury.EurJPharmacol.2013Dec5;721(1-3):5-11.[3].ZhuQ,etal.Antinociceptiveeffectsofsinomenineinaratmodelofneuropathicpain.SciRep.2014Dec1;4:7270.[4].WangMH,etal.Activationofopioidmu-receptorbysinomenineincellandmice.NeurosciLett.2008Oct10;443(3):209-12.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021-