Tafluprost-Standard-生命科學試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemETafluprost(Standard)Cat.No.:HY-B0600RCASNo.:209860-87-7分?式:C??H??F?O?分?量:452.53作?靶點:Others作?通路:Others儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Tafluprost(Standard)Tafluprost的分析標準品。本產品?于研究及分析應?。Tafluprost(AFP-168)抗青光眼前列腺素(PG)類似物。Tafluprost對視?膜神經節(jié)細胞(RGCs)和??RGCs細胞凋亡有抑制作?。Tafluprost通過調控Zn2+-mTOR通路促進軸突再?，抑制?眶前脂細胞細胞內脂質積累。Tafluprost可?于光眼視神經損傷研究。REFERENCES[1].Kuwayama,Y.andA.Nomura,Prospectiveobservationalpost-marketingstudyoftafluprostforglaucomaandocularhypertension:short-termefficacyandsafety.AdvTher,2014.31(4):p.461-71.[2].Kumagami,T.,etal.,Comparisonofcornealsafetyandintraocularpressure-loweringeffectoftafluprostophthalmicsolutionwithotherprostaglandinophthalmicsolutions.JOculPharmacolTher,2014.30(4):p.340-5.[3].Inoue,K.,A.Tanaka,andG.Tomita,Effectsoftafluprosttreatmentfor3yearsinpatientswithnormal-tensionglaucoma.ClinOphthalmol,2013.7:p.1411-6.[4].KanamoriA,etal.Tafluprostprotectsratretinalganglioncellsfromapoptosisinvitroandinvivo.GraefesArchClinExpOphthalmol.2009Oct;247(10):1353-60.[5].OtaT,etal.TheIOP-loweringeffectsandmechanismofactionoftafluprostinprostanoidreceptor-deficientmice.BrJOphthalmol.2007May;91(5):673-6.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792a