免疫治療科普英文

演講人：日期：免疫治療科普英文IntroductiontoImmunotherapyHowDoesImmunotherapyWork?BenefitsandRisksofImmunityLatestResearchandDevelopmentsinImmunotherapyAccessingandAffordabilityTreatments目錄01IntroductiontoImmunotherapyImmunotherapyisatypeofcancertreatmentthatusesthebody'sownimmunesystemtofitcancercellsItworksbystimulatingorrestoringtheimmunesystem'sabilitytorecognizeandattachcancercellsImmunotherapycanbeusedaloneorincombinationwithothercancertreatments,suchassurgery,chemotherapy,orradiationtherapyWhatisImmunotherapy?Earlyformsofhomologydatebacktothelate19thcenturywhendoctorsbeginusingbacteriaortoxinstostimulatetheimmunesystemInthe1970s,researchersdiscoveredthattheimmunesystemcouldbetrainedtorecognizeandattachcancercellsOverthepastdecade,therehasbeenasurgeinthedevelopmentofnewessentialdrugsandtechnologies,leadingtoimprovedoutcomesformanypatientsHistoryandDevelopmentofImmunotherapyThisisthebody'sfirstlineofdefenseagainstforeigninvaders,includingbacteria,viruses,andcancercellsItincludesphysicalbarriers(suchasskinandmucousmembranes)andchemicalbarriers(suchasacidsandenzymes)InnateImmunityThisisthebody'smorespecificandlonglastimmuneresponseItinvolvestheproductionofantibioticsandtheactivationofT-cellstotargetanddestroyspecificinvaders,includingcancercellsAdaptiveImmunityTypesofImmunities

WhoCanBenefitfromImmunotherapy?Patientswithcancertypesofcancer,suchasmalaria,lungcancer,andbladdercancer,maybenefitfromimmunotherapyImmunotherapymaybesignificantlyeffectiveforpatientswhohaverecurrentorspreaddespiteothertreatmentsSomepatientsmaybeeligibleforimmunotherapyaspartofaclinicaltrialtotestnewbugsorcombinationsoftreatments02HowDoesImmunotherapyWork?Immunotherapystimulatesthebody'sownimmunesystemtorecognizeandattachcancercellsImmunecheckpointinhibitorsarebugsthatblockcancerproteinsoncancercells,allowingtheimmunesystemtoidentifyanddestroythemCytokinesareproteinsthatstimulatetheimmunesystemandcanbeusedtoenhancethebody'sresponsetocancerSimulatingtheImmuneSystemMonoclonalantibioticsarelaboratoryproducedmoldsthatattachtospecifictargetsoncancercellsSpecificantibioticscansimilarlyattachtotwodifferentantibiotics,eitheronthesameordifferentcancercells,enhancingtheimmuneresponseAntibodydrugconnections(ADCs)areantibioticslinkedtocancerkillingdrugs,deliveringthemedicinedirectlytothetuitionsiteTargetingCancerCellswithAntibodies01ACTinvolvescollectingandusingpatients'ownimmunecells,whichhavebeenmodifiedtoattackcancercells02T-celltherapy,atypeofACT,involvingisolationandmultiplyingapatient'sT-cellsinthelaboratorybeforereintroducingthemintothebodytofitcancer03CART-celltherapyisaspecializedtypeofT-celltherapywheretheT-cellsaregeneticallymodifiedtoproducechiralantigenreceptors(CARs)thattargetspecificantigensoncancercellsAdaptiveCellTransfer(ACT)TherapeuticcancervaccinesstimulatetheimmunesystemtoattackspecificcancercellsPersonalizedvaccinesarecreatedusingapatient'sowntuberantstoelicitamoretargetedimmuneresponse單擊此處添加正文，文字是您思想的為了最終呈現(xiàn)發(fā)布的。單擊此處添加正文文字是您思。文字是您思。單擊此處添加正文文字是您思。文字是您思。4行*21字Dendriticcellvaccinesuseapatient'sowndendriticcells,whichareloadedwithcancerantigensandthenreintroducedintothebodytostimulateanimmuneresponseVaccinesforCancerTreatment03BenefitsandRisksofImmunityEnhancedimmuneresponseImmunotherapycanstimulatethebody'sownimmunesystemtorecognizeandattachcancercellsmoreeffectivelyTargetedtreatmentUnlikechemotherapy,whichaffectsbothhealthandcancercells,negligibletargetsspecificproteinsormarkersoncancercells,leavinghealthcellslargeunharmedDurableresponseInsomecases,negligiblecanprovidelongtermremittanceorevenacure,astheimmunesystemcontinuestofitthecancerevenaftertreatmenthasendedPotentialBenefitsofImmunoherapyInflammationandautoimmunereactionsImmunotherapycanstimulatesomeemotionswithanoveractiveimmuneresponse,leadingtoinflationorautoimmunediseasesAllergicreactionsSomeimmunotherapydrugscancauseAllergicreactions,rangingfrommilltosevereInfectionriskBecausetheimmunesystem,itcanincreasetheriskofinfectionCommonSideEffectsandRisksMedicalmanagementPrescriptiontreatmentscanbeusedtotreatinflammation,pain,andothersideeffectsLifestylemodificationsChangesindie,exercise,andsleephabitscanhelpreducetheseverityofsideeffectsandimproveoverallhealthClosemonitoringRegularcheckupsandbloodtestscanhelpidentifyandmanagesideeffectsearlyManagingSideEffectswithSupportingCareContinuousmonitoringEvenaftertreatmenthasended,regularcheckupsandmonitoringareimportanttoensurethatthecancerhasnotbeenreturnedPotentialforlongtermremovalInsomecases,negligiblecanprovidelongtermremovalorevenacureOngoingresearchanddevelopmentImmunotherapyisarapidlydevelopingfield,andnewtreatmentsandcombinationsoftreatmentsarecontinuouslybeingstudiedandtestedLongTermOutlookafterImmunotherapy04LatestResearchandDevelopmentsinImmunotherapyCombinationofImmunoherapyandChemotherapyCombiningimmunoherapybugswithchemotherapyhasshownpromiseresultsinshrinkingtubersandprolongingsurvivalinsomecancerpatientsImmunotherapyandRadiationTherapyRadiationtherapycanenhancetheeffectsofimmunitybyreleasingtumorantigensandstimulatingtheimmunesystemtoattackcancercellsTargetedTherapyandImmunotherapyTargetedtherapydrugsthatspecificallytargetcancercellsincancercellscanbecombinedwithimmunotherapytoachievebettertreatmentoutcomesCombinationTherapywithOtherTreatmentsGeneticTestingforPersonalizedTreatmentGenetictestingofstudentscanhelpidentifyspecificmutationsthatcanbetargetedbyimmunotherapydrugs,enablingpersonalizedtreatmentplansBiomerkerDrivenClinicalTrialsClinicaltrialsareincreasinglyfocusingonbiomarkerdrivenpatientselectiontoensurethattherightpatientsreceivethemosteffectiveimmunotherapytreatmentsDevelopmentofPersonalizedVacanciesPersonalizedVacanciesarebeingdevelopedthatstimulatestheimmunesystemtoattackspecifictuberantsuniquetoeachpatient'scancerPersonalizedMedicineandPrecisionImmunotherapy010203ImmuneCheckpointInhibitorsImmuneCheckpointInhibitorsareatypeofimmunitydrugthatblockscontainproteinsonimmunecells,allowingthemtoattackcancercellsmoreeffectivelyT-CellEngagingTherapyT-cellengagingtherapiesinvolvetheuseofengineeredT-cellsorantibioticsthatdirectT-cellstoattackcancercellsTumorInfiltratingLymphocytes(TILs)TILsareatypeofimmunecellfoundwithintutorsthatcanbeisolated,expanded,andreinfusedintopatientstoattacktheircancerNewTargetsforCancerImmunotherapyDevelopmentofMoreEffectandLessToxicImmunoherapyDrugsOngoingresearchisfocusedondevelopingnewimmunoherapydrugsthataremoreeffectiveandhavefeltsideeffectsthatarecurrenttreatmentsCombinationofImmunotherapywithOtherEmergingTechnologiesImmunotherapyisbeingcombinedwithotheremergingtechnologies,suchasgeneeditingandcelltherapy,tocreatemorepowerfulandtargetedtreatmentsforcancerUnderstandingtheRoleoftheMicrobiomeinImmunotherapyResponseResearchisalsoexploringtheroleofthemicrobiome(thecollectionofmicroorganismsinthebody)indeterminingapatient'sresponsetoimmunotherapytreatmentsFutureDirectionsinResearch05AccessingandAffordabilityTreatmentsSearchingOnlineDatabasesUtilizeonlineclinicaltrialdatabasesortreatmentcenterdirectoriestofindimmunodeficiencyoptionsConsultingwithHealthcareProvidersDiscussionswithyourhealthcareprovideraboutpotentialclinicaltrialsortreatmentcentersAttendingMedicalConferencesMedicalconferencesoftenprovideinformationaboutthelatestessentialresearchandtreatmentoptionsFindingClinicalTrialsorTreatmentCentersCostVariesbyTreatmentType01Thecostofnegligiblecanvarywidelydependingonthetypeoftreatment,suchasmonoclonalantibiotics,cancervaccines,orcellbasedtherapiesInsuranceCoverage02CheckwithyourinsuranceprovidertounderstandwhatessentialtreatmentsarecoveredandwhatoutofpocketcostsmaybeinvolvedCostBenefitAnalysis03ConsiderthepotentialbenefitsofimmunotherapyinrelationtoitscostUnderstandingtheCostofImmunotherapyPharmaceuticalCompanyProgramsManypharmaceutica