神經(jīng)病學 多發(fā)性硬化學習課件

重慶醫(yī)科大學臨床學院教案講稿PAGEPAGE6制表時間：2014年2月重慶醫(yī)科大學臨床學院教案及講稿（教案）課程名稱Neurology年級2010級授課專業(yè)心理系教師陳國俊職稱教授授課方式大課學時1題目章節(jié)Multiplesclerosis教材名稱神經(jīng)病學作者吳江出版社人民衛(wèi)生出版社版次2005年8月第一版教學目的要求DefinitionCausesClinicalmanifestationsInvestigationsDiagnosisTreatment教學難點ClinicalmanifestationsTreatment教學重點ClinicalmanifestationsTreatment外語要求English教學方法手段multimedia參考資料TextbookofNeurology.JulienBogousslavsky,M.D.教研室意見教學組長：王學峰教研室主任：王學峰2012年9月12日（講稿）教學內(nèi)容輔助手段時間分配Conception:MSischaracterizedbydestructionofthemyelinsheath(demyelinazation)andsubsequentlycausesaxonlosswithinthecentralnervoussystem.Factsheets:RiskforNewEngland:1per1,000Riskforidenticaltwin:1per3Riskforsibling:1per25-50Riskforparentorchild:1per100Cause:NotcompletelyunderstoodBlood-brainbarrierbreakdownandautoimmuneattackonCNSmyelinarethecentralpathogeneticeventsMSclassificationClinicallyisolatedsyndrome(CIS)(firstattack)臨床孤立綜合征Relapsing-remitting(60-70%)SecondaryprogressivePrimaryprogressiveClinicalfeature:Contracturesofjoints(limitsinjointrangeofmotion)UrinarytractinfectionsSkinulcersPainLaboratoryFindings:NospecificlaboratorytestsavailabletotestforMS.MRI’saremostoftenusedindiagnosingandmonitoringMSSpinaltaps:+IgGoligoclonalbanding(75–85%)Evokedpotentials:Lessactivationtostimulationoftheopticnerveandsensorynervesduetodemyelinationofsuchpathways.Diagnosis:2attacksAnattack(relapse;exacerbation)isdefinedaspatient-reportedorobjectivelyobservedeventstypicalofanacuteinflammatorydemyelinatingeventintheCNS,currentorhistorical,withdurationofatleast24hours,intheabsenceoffeverorinfection.Objectiveclinicalevidenceof2lesionsTreatment:ThereiscurrentlynocureforMS.Treatmentsfocuson:Slowingdownthedisease(diseasemodifying)AcuteattacksSpecificsymptomtreatment1min2min2min5min5min10min5min10min小結DefinitionofMSClassificationsofMSWhatarethemaininvestigationsofMS?思考題及預習DefinitionofMSClassificationsofMSWhatarethemaininvestigationsofMS?教案講稿質(zhì)量評價表權重評估內(nèi)容權重A好1.0-0.9B較好0.89-C一般0.79-D差0.59-0100編寫認真、教學態(tài)度端正10教學目的明確、概念清楚、內(nèi)容準確20教學注意系統(tǒng)性及先進性15重點突出、難點清楚15教學方法、手段適當10運用專業(yè)外語適當、準確10理論聯(lián)系實際、舉例恰