金屬鈷Co參與的光化學(xué)反應(yīng)最近30年的進展.ppt

金屬鈷（Co）參與的光化學(xué)反應(yīng)(最近30年的進展）,任磊（2012.04.14） 龔流柱課題組,鈷是一種化學(xué)元素，符號為Co，原子序數(shù)27，屬過渡金屬，具有磁性。1735年瑞典化學(xué)家布蘭特（G.Brandt）制出金屬鈷。 鈷的英文名稱“Cobalt”來自于德文的Kobold，意為“壞精靈”，因為鈷礦有毒，礦工、冶煉者常在工作時染病，鈷還會污染別的金屬，這些不良效果過去都被看作精靈的惡作劇,Vitamin B12,BrCoIII (salen)PPh3,CoII (salophen),Cobaloxime,Organocobalt,Inorganocobalt,一. Vitamin B12 Catalyred Radical Reactions,Scheffold, R.; Abrecht, S.; Orlinski, R.; Hans-Rudolf, R.; Stamouli, P.; Tinembart, 0.; Walder, L.; Weymuth, C. Pure Appl. Chem. 1987, 59, 363.,Scheffold, R.; Orlinski, R. J. Am. Chem. Soc. 1983, 105, 7200.,Orlinski, R.; Stankiewicz, T. Tetrahedron Lett. 1988, 29, 1601.,1.偶聯(lián)反應(yīng)（Heck-type） 2.C=N鍵的加成反應(yīng) 3.氧化化反應(yīng) 4.傅克反應(yīng) 5.其他反應(yīng),二. Organocobalt-Mediated Radical Reactions,(a) Schrauzer, G. N.；Windgassen，R. J. J. Am.Chem. Soc., 1966, 88, 3738. (b) Branchaud, B. P. J. Org. Chem. 1987,52, 212-217.,Branchaud, B. P. Tetrahedron Lett, , 1988, 29, 167.,Branchaud, B. P. J. Org. Chem. 1989,54. 1320.,機理,Branchaud, B. P. Tetrahedron Lett., 1988,.29,6037.,Branchaud, B. P. Tetrahedron.Lett.1991, 32, 6273.,Branchaud, B. P. Bio. Med. Chem. Lett. 1996, 6, 2289.,Carreira, E. M. Angew. Chem. Int. Ed. 2011, 50,11125,(a) Branchaud, B. P. Tetrahedmn Lett., 1994,35. 4071., (b) Branchaud, B. P. Tetrahedron Lett., 1993,34. 7885. (c) Branchaud, B. P. J. Org. Chem. 1998, 63. 3544,串聯(lián),Branchaud, B. P. J. Org. Chem. 1988,53, 4641.,Bruce P. Branchaud Tetrahedron Letters, 1988.29,6545. (b) Bruce P. Branchaud Tetrahedron Letters, 1991.32, 3639.,C=N 鍵加成,Bruce P. Branchaud, Tetrahedron Letters, 1997,38, 7009,(a) V. F. Patel. G. Pattenden. and J. J. Russell, Tetrahedron Lett 1986. 27. 2303 (b) H. Bhandal. G. Pattenden. and J. J. Russell. Tetrahedron Lett 1986, 27. 2299;,(a) D. J. Coveney, V. F. Patel, and G. Pattenden, Tetrahedron Lett., 1987, 28, 5949. (b) Vinod F. Patel and Gerald Pattenden, Tetrahedron Lett., 1988,29, 707.,100 W sunlamp,(a) V. F. Patel. G. Pattenden. and J. J. Russell, Tetrahedron Lett 1986. 27. 2303; (b) H. Bhandal. G. Pattenden. and J. J. Russell. Tetrahedron Lett 1986, 27. 2299; (c) M. Ladlow and G. Pattenden. ihicl 1983. 25, 4317;(d) M. J. Begley, M. Ladlow. and G. Pattenden, .Chem. Soc., Perkin Trcins. I , 1988, 1095.,Richard A. Earl and K. Peter C. Vollhardt. J. Am. Chem. Soc. 1983, 105, 6993.,(a) Aalbersberg, W. G. L.; Barkovich, A. J.; Funk, R. L.; Hilliard, R. L., III; Vollhardt, K. P. C. J. Am. Chem. Soc. 1975,97,5600; (b) Hilliard, R. L., 111; Vollhardt. K. P. C. J. Am. Chem. Soc. 1977,99,4058; c)Halter“, R. L.; Nguyen, N. H.; Vollhardt, K. P. C. J. Am. Chem. Soc. 1985,107, 1379.,三. Inorganocobalt-Mediated Radical Reactions,Gesing, E. R. F.; Tane, J. P.; Vollhardt, K. P. C. Angew. Chem. Int. Ed. 1980,19, 1023.,Brian L. Pagenkopf and Tom Livinghouse, J. Am. Chem. Soc. 1996, 118, 2285.,(a) Vollhardt, K.P.C. Angew.Chem.,Int. Ed.1984,23,539;(b)Barbara Heller, J. Org. Chem. 2002, 67, 4414-4422;(c) Barbara Heller, J. Org. Chem. 2003, 68, 9221-9225; (d)Pilar Prieto, Jos Ignacio Garca, Chem. Eur. J. 2012, ASAP,two 460 W lamps,C. Aubert, M. Malacria. Org. Lett. 2004. 6, 3937.,Marko Hapke, J. Org. Chem. 2010, 75, 3993.,K. Peter C. Vollhardt, Synlett, 1989, 15.,Malacria, M.; Vollhardt, K. P. C. J. Org. Chem. 1984, 49,5010,(a) Sheward, G. S.; Vollhardt, K. P. C. J. Org. Chem.1986,51,5491;(b) Grotjahn, D. B.; Vollhardt, K. P. C. J. Am. Chem. Soc. 1986,108