更年期抑郁的治療經(jīng)驗(yàn)課件

1、更年期抑郁的治療經(jīng)驗(yàn)1 Menopause and Depression Experience in Treatment George Linn, MD8:402-7. Terminology: Duration of Stage: Menstrual Cycles: Final Menstrual Period 更年期抑郁的治療經(jīng)驗(yàn)37 Vasomotor symptoms: Why dont we treat every women with hormones? 更年期抑郁的治療經(jīng)驗(yàn)38 Menopausal Complaints: Treatments /Hormones vs non-

2、hormones vs herbals /What kind of herbal drug is effective ? /Efficacy ? 更年期抑郁的治療經(jīng)驗(yàn)39 Clinical Event Hazard Ratio, 95% confidence interval HERS E+PWHI E+PWHI E alone CHD Events0.99 (0.80-1.22)1.29 (1.02-1.63)0.91 (0.75-1.12) Stroke1.23 (0.89-1.70)1.41 (1.07-1.85)1.39 (1.10-1.77) Pulm. Embolism2.79 (

3、0.89-8.75)2.13 (1.39-3.25)1.34 (0.87-2.06) Breast Cancer1.30 (0.77-2.19)1.26 (1.00-1.59)0.77 (0.59-1.01) Colon Cancer0.69 (0.32-1.49)0.63 (0.43-0.92)1.08 (0.75-1.55) Hip Fracture1.10 (0.49-2.50)0.66 (0.45-0.98)0.61 (0.41-0.91) Death1.08 (0.84-1.38)0.98 (0.82-1.18)1.04 (0.88-1.22) Global Index-1.15 (

4、1.03-1.28)1.01 (0.89-1.70) 更年期抑郁的治療經(jīng)驗(yàn)40 Hormones Contraindicated /Breast CA /Endometrial CA /Undiagnosed vaginal bleeding /CHD /Venous thrombosis /Stroke /Pregnancy /What is not here, that is a CI on OCPs? 更年期抑郁的治療經(jīng)驗(yàn)41 Specific Geriatric Issues Other assessments to be made. 更年期抑郁的治療經(jīng)驗(yàn)42 Cognitive Function /Normal decline /Dementia /Alzheimers /Vascular /Others /Depression /Medications /EtOH /MMSE 更年期抑郁的治療經(jīng)驗(yàn)43 Sensory /Visual /Auditory /Balance 更年期抑郁的治療經(jīng)驗(yàn)44 Polypharmacy /Medication List /Drug-dru